- Proteomic cell surface phenotyping of differentiating acute myeloid leukemia cells
[作者:Hofmann, A; Gerrits, B; Schmidt, A; Bock, T; Bausch-Fluck, D; Aebersold, R; Wollscheid, B,期刊:Blood, 页码:E26-E34 , 文章类型: Article,,卷期:2010年116-13]
- Immunophenotyping by flow cytometry or immunohistochemistry is a clinical standard procedure for diagnosis, classification, and monitoring of hematologic malignancies. Antibody-based cell surface phenotyping is commonly ...
- How I treat elderly patients with myeloma
[作者:Mehta, J; Cavo, M; Singhal, S,期刊:Blood, 页码:2215-2223 , 文章类型: Article,,卷期:2010年116-13]
- The clinical approach to older patients with myeloma has to be modified to take into account comorbidities and the likelihood of higher treatment-related toxicity. Individualization of management and adequate supportive ...
- Prognostic impact of monosomal karyotype in young adult and elderly acute myeloid leukemia: the Southwest Oncology Group (SWOG) experience
[作者:Medeiros, BC; Othus, M; Fang, M; Roulston, D; Appelbaum, FR,期刊:Blood, 页码:2224-2228 , 文章类型: Article,,卷期:2010年116-13]
- Monosomal karyotype (MK), defined as 2 or more monosomies, or a single monosomy in the presence of structural abnormalities, has recently been reported as identifying a distinct subset of acute myeloid leukemia (AML) pat...
- Multicenter survey on the outcome of transplantation of hematopoietic cells in patients with the complete form of DiGeorge anomaly
[作者:Janda, A; Sedlacek, P; Honig, M; Friedrich, W; Champagne, M; Matsumoto, T; Fischer, A; Neven, B; Contet, A; Bensoussan, D; Bordigoni, P; Loeb, D; Savage, W; Jabado, N; Bonilla, FA; Slatter, MA; Davies, EG; Gennery, AR,期刊:Blood, 页码:2229-2236 , 文章类型: Article,,卷期:2010年116-13]
- Seventeen patients transplanted with hematopoietic cells to correct severe T lymphocyte immunodeficiency resulting from complete DiGeorge anomaly were identified worldwide, and retrospective data were obtained using a qu...
- A population-based study of cardiac morbidity among Hodgkin lymphoma patients with preexisting heart disease
[作者:Myrehaug, S; Pintilie, M; Yun, LS; Crump, M; Tsang, RW; Meyer, RM; Sussman, J; Yu, E; Hodgson, DC,期刊:Blood, 页码:2237-2240 , 文章类型: Article,,卷期:2010年116-13]
- The risk of cardiac hospitalization (CH) in Hodgkin lymphoma (HL) patients with preexisting heart disease was evaluated. Patients with HL were identified from a population-based registry (N = 3964). Data were abstracted ...
- Radioimmunodetection of amyloid deposits in patients with AL amyloidosis
[作者:Wall, JS; Kennel, SJ; Stuckey, AC; Long, MJ; Townsend, DW; Smith, GT; Wells, KJ; Fu, YT; Stabin, MG; Weiss, DT; Solomon, A,期刊:Blood, 页码:2241-2244 , 文章类型: Article,,卷期:2010年116-13]
- Care of patients with AL amyloidosis currently is limited by the lack of objective means to document disease extent, as well as therapeutic options that expedite removal of pathologic deposits. To address these issues, w...
- Expansion of EBNA1-specific effector T cells in posttransplantation lymphoproliferative disorders
[作者:Jones, K; Nourse, JP; Morrison, L; Nguyen-Van, D; Moss, DJ; Burrows, SR; Gandhi, MK,期刊:Blood, 页码:2245-2252 , 文章类型: Article,,卷期:2010年116-13]
- Immunosuppression resulting in impaired Epstein-Barr virus (EBV)-specific T-cell immunity is involved in the pathogenesis of EBV-positive post-transplantation lymphoproliferative disorder (EBV+ PTLD). Restoration of EBV-...
- High-resolution mapping of prostaglandin E-2-dependent signaling networks identifies a constitutively active PKA signaling node in CD8(+)CD45RO(+) T cells
[作者:Oberprieler, NG; Lemeer, S; Kalland, ME; Torgersen, KM; Heck, AJR; Tasken, K,期刊:Blood, 页码:2253-2265 , 文章类型: Article,,卷期:2010年116-13]
- To analyze prostaglandin E-2(PGE(2)) signaling in lymphoid cells, we introduce a multipronged strategy, combining temporal quantitative phosphoproteomics and phospho flow cytometry. We describe the PGE(2)-induced phospho...
- Crucial roles of B7-H1 and B7-DC expressed on mesenteric lymph node dendritic cells in the generation of antigen-specific CD4(+)Foxp3(+) regulatory T cells in the establishment of oral tolerance
[作者:Fukaya, T; Takagi, H; Sato, Y; Sato, K; Eizumi, K; Taya, H; Shin, T; Chen, LP; Dong, C; Azuma, M; Yagita, H; Malissen, B; Sato, K,期刊:Blood, 页码:2266-2276 , 文章类型: Article,,卷期:2010年116-13]
- Oral tolerance is a key feature of intestinal immunity, generating systemic tolerance to fed antigens. However, the molecular mechanism mediating oral tolerance remains unclear. In this study, we examined the role of the...
- Targeting of DEC-205 on human dendritic cells results in efficient MHC class II-restricted antigen presentation
[作者:Birkholz, K; Schwenkert, M; Kellner, C; Gross, S; Fey, G; Schuler-Thurner, B; Schuler, G; Schaft, N; Dorrie, J,期刊:Blood, 页码:2277-2285 , 文章类型: Article,,卷期:2010年116-13]
- The use of dendritic cells (DCs) in therapeutic cancer vaccination requires their loading with tumor-specific antigen(s). DEC-205, a phagocytosis receptor mediating antigen uptake, is associated with CD8(+) T-cell respon...
- The PD-1/PD-L1 axis modulates the natural killer cell versus multiple myeloma effect: a therapeutic target for CT-011, a novel monoclonal anti-PD-1 antibody
[作者:Benson, DM; Bakan, CE; Mishra, A; Hofmeister, CC; Efebera, Y; Becknell, B; Baiocchi, RA; Zhang, JY; Yu, JH; Smith, MK; Greenfield, CN; Porcu, P; Devine, SM; Rotem-Yehudar, R; Lozanski, G; Byrd, JC; Caligiuri, MA,期刊:Blood, 页码:2286-2294 , 文章类型: Article,,卷期:2010年116-13]
- T-cell expression of programmed death receptor-1 (PD-1) down-regulates the immune response against malignancy by interacting with cognate ligands (eg, PD-L1) on tumor cells; however, little is known regarding PD-1 and na...
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