- Prevalence and predictors of chronic health conditions after hematopoietic cell transplantation: a report from the Bone Marrow Transplant Survivor Study
[作者:Sun, CL; Francisco, L; Kawashima, T; Leisenring, W; Robison, LL; Baker, KS; Weisdorf, DJ; Forman, SJ; Bhatia, S,期刊:Blood, 页码:3129-3139 , 文章类型: Article,,卷期:2010年116-17]
- Long-term survival is now an expected outcome after hematopoietic cell transplantation (HCT). However, the burden of morbidity long-term after HCT remains unknown. We examined the magnitude of risk of chronic health cond...
- Systematic review and meta-analysis methodology
[作者:Crowther, M; Lim, W; Crowther, MA,期刊:Blood, 页码:3140-3146 , 文章类型: Review,,卷期:2010年116-17]
- Systematic reviews and meta-analyses are being increasingly used to summarize medical literature and identify areas in which research is needed. Systematic reviews limit bias with the use of a reproducible scientific pro...
- How I treat acute myeloid leukemia
[作者:Rowe, JM; Tallman, MS,期刊:Blood, 页码:3147-3156 , 文章类型: Article,,卷期:2010年116-17]
- More than one quarter of a million adults throughout the world are diagnosed annually with acute myeloid leukemia (AML). Despite considerable progress during the past 3 decades in the therapy of AML, two-thirds of young ...
- Higher incidence of relapse in patients with acute myelocytic leukemia infused with higher doses of CD34(+) cells from leukapheresis products autografted during the first remission
[作者:Gorin, NC; Labopin, M; Reiffers, J; Milpied, N; Blaise, D; Witz, F; de Witte, T; Meloni, G; Attal, M; Bernal, T; Rocha, V,期刊:Blood, 页码:3157-3162 , 文章类型: Article,,卷期:2010年116-17]
- The stem cell source for autologous transplantation has shifted from bone marrow to peripheral blood (PB). We previously showed that relapse incidence in patients with acute myelocytic leukemia autografted in first remis...
- Phase 2 study of romiplostim in patients with low- or intermediate-risk myelodysplastic syndrome receiving azacitidine therapy
[作者:Kantarjian, HM; Giles, FJ; Greenberg, PL; Paquette, RL; Wang, ES; Gabrilove, JL; Garcia-Manero, G; Hu, KL; Franklin, JL; Berger, DP,期刊:Blood, 页码:3163-3170 , 文章类型: Article,,卷期:2010年116-17]
- We evaluated the efficacy and safety of romiplostim, a thrombopoietin mimetic, in patients with low-or intermediate-risk myelodysplastic syndromes (MDS) receiving azacitidine therapy. Forty patients with low-or intermedi...
- Front-line treatment of acute promyelocytic leukemia with AIDA induction followed by risk-adapted consolidation for adults younger than 61 years: results of the AIDA-2000 trial of the GIMEMA Group
[作者:Lo-Coco, F; Avvisati, G; Vignetti, M; Breccia, M; Gallo, E; Rambaldi, A; Paoloni, F; Fioritoni, G; Ferrara, F; Specchia, G; Cimino, G; Diverio, D; Borlenghi, E; Martinelli, G; Di Raimondo, F; Di Bona, E; Fazi, P; Peta, A; Bosi, A; Carella, AM; Fabbiano, F; Pogliani, EM; Petti, MC; Amadori, S; Mandelli, F,期刊:Blood, 页码:3171-3179 , 文章类型: Article,,卷期:2010年116-17]
- After the identification of discrete relapse-risk categories in patients with acute promyelocytic leukemia (APL) receiving all-trans retinoic and idarubicin (AIDA)-like therapies, the Gruppo Italiano Malattie Ematologich...
- High response rate and durable remissions following fludarabine and rituximab combination therapy for chronic cold agglutinin disease
[作者:Berentsen, S; Randen, U; Vagan, AM; Hjorth-Hansen, H; Vik, A; Dalgaard, J; Jacobsen, EM; Thoresen, AS; Beiske, K; Tjonnfjord, GE,期刊:Blood, 页码:3180-3184 , 文章类型: Article,,卷期:2010年116-17]
- Most patients diagnosed with primary chronic cold agglutinin disease (CAD) have a clonal lymphoproliferative bone marrow disorder. Treatment with rituximab is the only well-documented effective therapy, leading to 45%-60...
- Phenotypically identical hemopoietic stem cells isolated from different regions of bone marrow have different biologic potential
[作者:Grassinger, J; Haylock, DN; Williams, B; Olsen, GH; Nilsson, SK,期刊:Blood, 页码:3185-3196 , 文章类型: Article,,卷期:2010年116-17]
- Hemopoietic stem cells (HSCs) reside within a specified area of the bone marrow (BM) cavity called a "niche" that modulates HSC quiescence, proliferation, differentiation, and migration. Our previous studies have identif...
- Elevated Mcl-1 perturbs lymphopoiesis, promotes transformation of hematopoietic stem/progenitor cells, and enhances drug resistance
[作者:Campbell, KJ; Bath, ML; Turner, ML; Vandenberg, CJ; Bouillet, P; Metcalf, D; Scott, CL; Cory, S,期刊:Blood, 页码:3197-3207 , 文章类型: Article,,卷期:2010年116-17]
- Diverse human cancers with poor prognosis, including many lymphoid and myeloid malignancies, exhibit high levels of Mcl-1. To explore the impact of Mcl-1 overexpression on the hematopoietic compartment, we have generated...
- ITAM signaling in dendritic cells controls T helper cell priming by regulating MHC class II recycling
[作者:Graham, DB; Akilesh, HM; Gmyrek, GB; Piccio, L; Gilfillan, S; Sim, J; Belizaire, R; Carrero, JA; Wang, YA; Blaufuss, GS; Sandoval, G; Fujikawa, K; Cross, AH; Russell, JH; Cella, M; Swat, W,期刊:Blood, 页码:3208-3218 , 文章类型: Article,,卷期:2010年116-17]
- Immature dendritic cells (DCs) specialize in antigen capture and maintain a highly dynamic pool of intracellular major histocompatibility complex class II (MHCII) that continuously recycles from peptide loading compartme...
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