- Resveratrol is an effective inducer of CArG-driven TNF-alpha gene therapy
[作者：Bickenbach, KA; Veerapong, J; Shao, MY; Mauceri, HJ; Posner, MC; Kron, SJ; Weichselbaum, RR,期刊：Cancer gene therapy, 页码：133-139 , 文章类型： Article，,卷期：2008年15-3]
- We report the anticarcinogenic, anti-aging polyphenol resveratrol activates the radio- and chemo-inducible cancer gene therapy vector Ad. Egr.TNF, a replication-deficient adenovirus that expresses human tumor necrosis fa...
- New highly potent and specific E6 and E7 siRNAs for treatment of HPV16 positive cervical cancer
[作者：Yamato, K; Yamada, T; Kizaki, M; Ui-Tei, K; Natori, Y; Fujino, M; Nishihara, T; Ikeda, Y; Nasu, Y; Saigo, K; Yoshinouchi, M,期刊：Cancer gene therapy, 页码：140-153 , 文章类型： Article，,卷期：2008年15-3]
- Persistent infection by high-risk types of human papillomaviruses (HPV) is a necessary cause of cervical cancer, with HPV16 the most prevalent, accounting for more than 50% of reported cases. The virus encodes the E6 and...
- Adenoviral vector transduction of the human deoxycytidine kinase gene enhances the cytotoxic and radiosensitizing effect of gemcitabine on experimental gliomas
[作者：Szatmari, T; Huszty, G; Desaknai, S; Spasokoukotskaja, T; Sasvari-Szekely, M; Staub, M; Esik, O; Safrany, G; Lumniczky, K,期刊：Cancer gene therapy, 页码：154-164 , 文章类型： Article，,卷期：2008年15-3]
- The aim of this work was to improve the cytotoxic and radiosensitizing effects of gemcitabine using a gene-directed enzyme prodrug therapy approach. Murine Gl261, rat C6 and human U373 glioma cell lines were transduced w...
- A simplified system for generating oncolytic adenovirus vector carrying one or two transgenes
[作者：Hu, ZB; Wu, CT; Wang, H; Zhang, QW; Wang, L; Wang, RL; Lu, ZZ; Wang, LS,期刊：Cancer gene therapy, 页码：173-182 , 文章类型： Article，,卷期：2008年15-3]
- Oncolytic adenoviruses, also called conditionally replicating adenoviruses (CRADs), have been widely applied in cancer gene therapy. However, the construction of CRADs is still time-consuming. In this study, we attempted...
- An improved human carboxylesterase for enzyme/prodrug therapy with CPT-11
[作者：Wierdl, M; Tsurkan, L; Hyatt, JL; Edwards, CC; Hatfield, MJ; Morton, CL; Houghton, PJ; Danks, MK; Redinbo, MR; Potter, PM,期刊：Cancer gene therapy, 页码：183-192 , 文章类型： Article，,卷期：2008年15-3]
- CPT-11 is a potent antitumor agent that is activated by carboxylesterases (CE) and intracellular expression of CEs that can activate the drug results in increased cytotoxicity to the drug. As activation of CPT-11 (irinot...
- Calcium carbonate nanoparticle delivering vascular endothelial growth factor-C siRNA effectively inhibits lymphangiogenesis and growth of gastric cancer in vivo
[作者：He, XW; Liu, T; Chen, YX; Cheng, DJ; Li, XR; Xiao, Y; Feng, YL,期刊：Cancer gene therapy, 页码：193-202 , 文章类型： Article，,卷期：2008年15-3]
- A nonviral gene carrier, calcium carbonate (CaCO3) nanoparticle, was evaluated for efficient in vitro and in vivo delivery of small interfering RNA (siRNA) targeting vascular endothelial growth factor-C (VEGF-C). The che...
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