- Fluorescence and UV Resonance Raman Study of Peptide-Vesicle Interactions of Human Cathelicidin LL-37 and Its F6W and F17W Mutants
[作者:Gable, JE; Schlamadinger, DE; Cogen, AL; Gallo, RL; Kim, JE,期刊:Biochemistry, 页码:11264-11272 , 文章类型: Article,,卷期:2009年48-47]
- LL-37 is a broad-spectrum human antimicrobial peptide in the cathelicidin family. Potency assays in the form of minimal inhibitory concentration and vesicle leakage indicate that the single-tryptophan mutants, F6W and F1...
- A FRET-Based Method for Probing the Conformational Behavior of an Intrinsically Disordered Repeat Domain from Bordetella pertussis Adenylate Cyclase
[作者:Szilvay, GR; Blenner, MA; Shur, O; Cropek, DM; Banta, S,期刊:Biochemistry, 页码:11273-11282 , 文章类型: Article,,卷期:2009年48-47]
- A better understanding of the conformational changes exhibited by intrinsically disordered proteins is necessary as we continue to unravel their myriad biological functions. In repeats in toxin (RTX) domains, calcium bin...
- Structural Basis of the Aberrant Receptor Binding Properties of Hagfish and Lamprey Insulins
[作者:Sajid, W; Holst, PA; Kiselyov, VV; Andersen, AS; Conlon, JM; Kristensen, C; Kjeldsen, T; Whittaker, J; Chan, SJ; De Meyts, P,期刊:Biochemistry, 页码:11283-11295 , 文章类型: Article,,卷期:2009年48-47]
- The insulin from the Atlantic hagfish (Myxine glutinosa) has been one of the most studied insulins from both a structural and a biological viewpoint; however, some aspects of its biology remain controversial, and there h...
- Dynamics and Energetics of the Base Flipping Conformation Studied with Base Pair-Mimic Nucleosides
[作者:Nakano, S; Oka, H; Uotani, Y; Uenishi, K; Fujii, M; Sugimoto, N,期刊:Biochemistry, 页码:11304-11311 , 文章类型: Article,,卷期:2009年48-47]
- A base flipping conformation is found in many biological processes, including DNA repair and DNA and RNA modification processes. To investigate the dynamics and energetics of this unusual conformation in a double helix, ...
- pH-Dependent Configurations of a 5-Chlorouracil-Guanine Base Pair
[作者:Theruvathu, JA; Kim, CH; Darwanto, A; Neidigh, JW; Sowers, LC,期刊:Biochemistry, 页码:11312-11318 , 文章类型: Article,,卷期:2009年48-47]
- Hypochlorous acid (HOCl) from activated neutrophils at sites of inflammation can react with and damage biological molecules, including nucleic acids. The reaction of HOCl with cytosine analogues can generate multiple pro...
- Interaction of the Tim44 C-Terminal Domain with Negatively Charged Phospholipids
[作者:Marom, M; Safonov, R; Amram, S; Avneon, Y; Nachliel, E; Gutman, M; Zohary, K; Azem, A; Tsfadia, Y,期刊:Biochemistry, 页码:11185-11195 , 文章类型: Article,,卷期:2009年48-47]
- The translocation of proteins from the cytosol into the mitochondrial matrix is mediated by the coordinated action of the TOM complex in the Outer membrane, as well as the TIM23 complex and its associated protein import ...
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