- Rapalogs in viral cancers
[作者:Dittmer, DP; Bhatt, AP; Damania, B,期刊:Expert opinion on investigational drugs, 页码:135-138 , 文章类型: Editorial Material,,卷期:2012年21-2]
- At present, 150 clinical trials are registered with the National Cancer Institute, which investigate the efficacy of inhibitors of the PI3K/Akt/mTOR pathway against multiple cancers. Efficacy varies not so much with drug...
- Glial modulators: a novel pharmacological approach to altering the behavioral effects of abused substances
[作者:Cooper, ZD; Jones, JD; Comer, SD,期刊:Expert opinion on investigational drugs, 页码:169-178 , 文章类型: Review,,卷期:2012年21-2]
- Introduction: Commonly abused drugs including opioids, stimulants and alcohol activate glia cells, an effect that has been identified across species. Glia, specifically astrocytes and microglia, have been shown to contri...
- Targeting the subtypes of breast cancer: rethinking investigational drugs
[作者:Curigliano, G; Locatelli, M; Fumagalli, L; Brollo, J; Munzone, E; Nole, F; Criscitiello, C; Goldhirsch, A,期刊:Expert opinion on investigational drugs, 页码:191-204 , 文章类型: Review,,卷期:2012年21-2]
- Introduction: The choice of adjuvant treatments for women with breast cancer is based on several features that take into account the heterogeneity of the disease. Questions raised during the decision process include the ...
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