- Glutaminyl Cyclases Display Significant Catalytic Proficiency for Glutamyl Substrates
[作者：Seifert, F; Schulz, K; Koch, B; Manhart, S; Demuth, HU; Schilling, S,期刊：Biochemistry, 页码：11831-11833 , 文章类型： Article，,卷期：2009年48-50]
- N-Terminal glutaminyl and glutamyl residues of peptides and proteins tend to form pyroglutamic acid (pGlu) by intramolecular cylization. The rate constants for spontaneous cyclization of glutamine (10(-6) s(-1)) and glut...
- A Peptide Tag System for Facile Purification and Single-Molecule Immobilization
[作者：Huang, J; Nagy, SS; Koide, A; Rock, RS; Koide, S,期刊：Biochemistry, 页码：11834-11836 , 文章类型： Article，,卷期：2009年48-50]
- A peptide fusion tag and accompanying recombinant capture reagents have been developed oil the basis of the peptide-PDZ domain interaction and affinity clamps, a new class of affinity reagent. This system allows for sing...
- Nonspecificity of Binding of gamma-Secretase Modulators to the Amyloid Precursor Protein
[作者：Beel, AJ; Barrett, P; Schnier, PD; Hitchcock, SA; Bagal, D; Sanders, CR; Jordan, JB,期刊：Biochemistry, 页码：11837-11839 , 文章类型： Article，,卷期：2009年48-50]
- Evidence that certain gamma-secretase modulators (GSMs) target the 99-residue C-terminal domain (C99) of the amyloid precursor protein, a substrate of gamma-secretase, but not the protease complex itself has been present...
- Biochemical Characterization of the RNase II Family of Exoribonucleases from the Human Pathogens Salmonella typhimurium and Streptococcus pneumoniae
[作者：Domingues, S; Matos, RG; Reis, FP; Fialho, AM; Barbas, A; Arraiano, CM,期刊：Biochemistry, 页码：11848-11857 , 文章类型： Article，,卷期：2009年48-50]
- Maturation, turnover, and quality control of RNA are performed by many different classes of ribonucleases. Escherichia coli RNase II is the prototype of the RNase II family of ribonucleases, a ubiquitous family of hydrol...
- Macrophage Scavenger Receptor A Mediates Adhesion to Apolipoproteins A-I and E
[作者：Neyen, C; Pluddemann, A; Roversi, P; Thomas, B; Cai, L; van der Westhuyzen, DR; Sim, RB; Gordon, S,期刊：Biochemistry, 页码：11858-11871 , 文章类型： Article，,卷期：2009年48-50]
- Macrophage scavenger receptor A (SR-A) is a multifunctional, multiligand pattern recognition receptor with roles in innate immunity, apoptotic cell clearance, and age-related degenerative pathologies, such as atheroscler...
- Design and Pharmacological Characterization of Inhibitors of Amantadine-Resistant Mutants of the M2 Ion Channel of Influenza A Virus
[作者：Balannik, V; Wang, J; Ohigashi, Y; Jing, XH; Magavern, E; Lamb, RA; DeGrado, WF; Pinto, LH,期刊：Biochemistry, 页码：11872-11882 , 文章类型： Article，,卷期：2009年48-50]
- The A/M2 proton channel of influenza A virus is a target for the anti-influenza drugs amantadine and rimantadine, whose effectiveness was diminished by the appearance of naturally occurring point mutants in the A/M2 chan...
- Influence of Proline upon the Folding and Geometry of the WALP19 Transmembrane Peptide
[作者：Thomas, R; Vostrikov, VV; Greathouse, DV; Koeppe, RE,期刊：Biochemistry, 页码：11883-11891 , 文章类型： Article，,卷期：2009年48-50]
- The orientations, geometries, and lipid interactions of designed transmembrane (TM) peptides have attracted significant experimental and theoretical interest. Because the amino acid proline will introduce a known discont...
- Solution Structure and Membrane Interactions of the Antimicrobial Peptide Fallaxidin 4.1a: An NMR and QCM Study
[作者：Sherman, PJ; Jackway, RJ; Gehman, JD; Praporski, S; McCubbin, GA; Mechler, A; Martin, LL; Separovic, F; Bowie, JH,期刊：Biochemistry, 页码：11892-11901 , 文章类型： Article，,卷期：2009年48-50]
- The solution structure of fallaxidin 4.1a, a C-terminal amidated analogue of fallaxidin 4.1, a cationic antimicrobial peptide isolated from the amphibian Litoria fallax, has been determined by nuclear magnetic resonance ...
- Asp157 Is Required for the Function of PsbO, the Photosystem II Manganese Stabilizing Protein
[作者：Popelkova, H; Commet, A; Yocum, CF,期刊：Biochemistry, 页码：11920-11928 , 文章类型： Article，,卷期：2009年48-50]
- PsbO, the photosystem II manganese stabilizing protein, contains an aspartate residue [Asp157 (spinach numbering)], which Is highly conserved in eukaryotic and prokaryotic PsbOs. The homology model of the PSII-bound conf...
- Dss1 Regulates Interaction of Brh2 with DNA
[作者：Zhou, QW; Mazloum, N; Mao, NH; Kojic, M; Holloman, WK,期刊：Biochemistry, 页码：11929-11938 , 文章类型： Article，,卷期：2009年48-50]
- Brh2, the BRCA2 homologue in Ustilago maydis, plays a crucial role in homologous recombination by controlling Rad51. In turn, Brh2 is governed by Dss1, an intrinsically disordered protein that forms a tight complex with ...
- The Human Papillomavirus E7-E2 Interaction Mechanism in Vitro Reveals a Finely Tuned System for Modulating Available E7 and E2 Proteins
[作者：Smal, C; Wetzler, DE; Dantur, KI; Chemes, LB; Garcia-Alai, MM; Dellarole, M; Alonso, LG; Gaston, K; de Prat-Gay, G,期刊：Biochemistry, 页码：11939-11949 , 文章类型： Article，,卷期：2009年48-50]
- Transcription of the human papillomavirus E7 oncoprotein is negatively controlled by the viral E2 protein, and loss of this repression leads to irreversible transformation and carcinogenesis. Here we show that interactio...
- Role of the Nuclear Receptors HNF4 alpha, PPAR alpha, and LXRs in the TNF alpha-Mediated Inhibition of Human Apolipoprotein A-I Gene Expression in HepG2 Cells
[作者：Mogilenko, DA; Dizhe, EB; Shavva, VS; Lapikov, IA; Orlov, SV; Perevozchikov, AP,期刊：Biochemistry, 页码：11950-11960 , 文章类型： Article，,卷期：2009年48-50]
- The expression of the apolipoprotein A-I gene (apoA-I) in hepatocytes is repressed by pro-inflammatory cytokines such as IL-1 beta and TNF alpha. In this work, we have demonstrated that treatment of HepG2 human hepatoma ...
- Competition between Co(NH3)(6)(3+) and Inner Sphere Mg2+ Ions in the HDV Ribozyme
[作者：Gong, B; Chen, JH; Bevilacqua, PC; Golden, BL; Carey, PR,期刊：Biochemistry, 页码：11961-11970 , 文章类型： Article，,卷期：2009年48-50]
- Divalent cations play critical structural and functional roles in many RNAs. While the hepatitis delta virus (HDV) ribozyme can undergo self-cleavage in the presence of molar concentrations of monovalent cations, divalen...
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