- The synergetic bone-forming effects of combinations of growth factors expressed by adenovirus vectors on chitosan/collagen scaffolds
[作者:Zhang, YF; Shi, B; Li, CZ; Wang, YN; Chen, Y; Zhang, W; Luo, T; Cheng, XR,期刊:Journal of controlled release, 页码:172-178 , 文章类型: Article,,卷期:2009年136-3]
- Supporting and enhancing the regeneration and stability of alveolar bone at dental implant sites is necessary to improve implant integration and stability. In this study chitosan/collagen scaffolds combined with adenovir...
- Encapsulation of the synthetic retinoids Am80 and LE540 into polymeric micelles and the retinoids' release control
[作者:Satoh, T; Higuchi, Y; Kawakami, S; Hashida, M; Kagechika, H; Shudo, K; Yokoyama, M,期刊:Journal of controlled release, 页码:187-195 , 文章类型: Article,,卷期:2009年136-3]
- The objective of this study was to encapsulate two synthetic retinoids Am80 and LE540 into polymeric micelles and to control the retinoids' release rate in vitro. Highly efficient encapsulation yields of these retinoids ...
- A new model of resorbable device degradation and drug release: Transient 1-dimension diffusional model
[作者:Perale, G; Arosio, P; Moscatelli, D; Barri, V; Muller, M; Maccagnan, S; Masi, M,期刊:Journal of controlled release, 页码:196-205 , 文章类型: Article,,卷期:2009年136-3]
- In the framework of resorbable devices, an increased demand for a better reliability in drug delivery systems emerged, based on resorbable polymers degradation control. These points influenced researchers to replace the ...
- Coated formulations: New insights into the release mechanism and changes in the film properties with a novel release cell
[作者:Marucci, M; Hjartstam, J; Ragnarsson, G; Iselau, F; Axelsson, A,期刊:Journal of controlled release, 页码:206-212 , 文章类型: Article,,卷期:2009年136-3]
- The effect of the blend ratio of water-insoluble ethyl cellulose (EC) and water-soluble hydroxypropyl cellulose (HPC-LF), on the properties of sprayed films and on the drug release mechanism of formulations coated with t...
- Pulmonary gene delivery of hybrid vector, lipopolyplex containing N-lauroylsarcosine, via the systemic route
[作者:Kurosaki, T; Kishikawa, R; Matsumoto, M; Kodama, Y; Hamamoto, T; To, H; Niidome, T; Takayama, K; Kitahara, T; Sasaki, H,期刊:Journal of controlled release, 页码:213-219 , 文章类型: Article,,卷期:2009年136-3]
- We newly prepared lipopolyplexes containing N-lauroylsarcosine (LS) as a hybrid vector for pulmonary gene delivery via the systemic route. Lipopolyplexes were composed of polyethylenimine (PEI), N-[1-(2,3-dioleyloxy) pro...
- A matrix reservoir for improved control of non-viral gene delivery
[作者:Holladay, C; Keeney, M; Greiser, U; Murphy, M; O'Brien, T; Pandit, A,期刊:Journal of controlled release, 页码:220-225 , 文章类型: Article,,卷期:2009年136-3]
- Non-viral gene delivery suffers from a number of limitations including short transgene expression times and low transfection efficiency. Collagen scaffolds have previously been investigated as in vitro DNA reservoirs, wh...
- Pharmacokinetics of single and repeated injection of hemoglobin-vesicles in hemorrhagic shock rat model
[作者:Taguchi, K; Maruyama, T; Iwao, Y; Sakai, H; Kobayashi, K; Horinouchi, H; Tsuchida, E; Kai, T; Otagiri, M,期刊:Journal of controlled release, 页码:232-239 , 文章类型: Article,,卷期:2009年136-3]
- Hemoglobin-vesicles (HbV) are liposomal artificial oxygen carriers that may be useful as a resuscitation fluid during hemorrhagic shock (HS). It is well-known that the pharmacokinetic properties of liposome change in res...
- Design and evaluation of a liposomal delivery system targeting the posterior segment of the eye
[作者:Hironaka, K; Inokuchi, Y; Tozuka, Y; Shimazawa, M; Hara, H; Takeuchi, H,期刊:Journal of controlled release, 页码:247-253 , 文章类型: Article,,卷期:2009年136-3]
- The purpose of this study was to evaluate the potential of submicron-sized liposomes (ssLips) as a novel system for delivering ocular drugs to the eye's posterior segment. Fluorescence emission of coumarin-6 formulated i...
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