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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共38条记录   Erythrocyte membrane changes of chorea-acanthocytosis are the result of altered Lyn kinase activity [作者：De Franceschi, L; Tomelleri, C; Matte, A; Brunati, AM; Bovee-Geurts, PH; Bertoldi, M; Lasonder, E; Tibaldi, E; Danek, A; Walker, RH; Jung, HH; Bader, B; Siciliano, A; Ferru, E; Mohandas, N; Bosman, GJCGM,期刊：Blood, 页码：5652-5663 , 文章类型： Article，,卷期：2011年118-20] Acanthocytic RBCs are a peculiar diagnostic feature of chorea-acanthocytosis (ChAc), a rare autosomal recessive neurodegenerative disorder. Although recent years have witnessed some progress in the molecular characteriza... Epigenetic and molecular profiles of erythroid cells after hydroxyurea treatment in sickle cell anemia [作者：Walker, AL; Steward, S; Howard, TA; Mortier, N; Smeltzer, M; Wang, YD; Ware, RE,期刊：Blood, 页码：5664-5670 , 文章类型： Article，,卷期：2011年118-20] Hydroxyurea has been shown to be efficacious for the treatment of sickle cell anemia (SCA), primarily through the induction of fetal hemoglobin (HbF). However, the exact mechanisms by which hydroxyurea can induce HbF rem... Ex vivo expansion of human Tregs specific for alloantigens presented directly or indirectly [作者：Veerapathran, A; Pidala, J; Beato, F; Yu, XZ; Anasetti, C,期刊：Blood, 页码：5671-5680 , 文章类型： Article，,卷期：2011年118-20] Adoptive transfer of regulatory T cells (Tregs) prevents GVHD in experimental animals. Because antigen activation drives Treg function, we measured the frequency, growth requirements, and function of alloantigen-specific... Preemptive immunotherapy in childhood acute myeloid leukemia for patients showing evidence of mixed chimerism after allogeneic stem cell transplantation [作者：Rettinger, E; Willasch, AM; Kreyenberg, H; Borkhardt, A; Holter, W; Kremens, B; Strahm, B; Woessmann, W; Mauz-Koerholz, C; Gruhn, B; Burdach, S; Albert, MH; Schlegel, PG; Klingebiel, T; Bader, P,期刊：Blood, 页码：5681-5688 , 文章类型： Article，,卷期：2011年118-20] Previous studies have shown that children with acute myeloid leukemia (AML) who developed mixed chimerism (MC) were at high risk for relapse after allogeneic stem-cell transplantation (allo-SCT). We investigated the feas... Intensive strategy to prevent CMV disease in seropositive umbilical cord blood transplant recipients [作者：Milano, F; Pergam, SA; Xie, H; Leisenring, WM; Gutman, JA; Riffkin, I; Chow, V; Boeckh, MJ; Delaney, C,期刊：Blood, 页码：5689-5696 , 文章类型： Article，,卷期：2011年118-20] Seropositive umbilical cord blood transplant (UCBT) recipients are at increased risk for CMV complications. To reduce CMV complications, we adopted an intensive strategy that consisted of ganciclovir administered before ... Allogeneic stem cell transplantation for patients harboring T315I BCR-ABL mutated leukemias [作者：Nicolini, FE; Basak, GW; Soverini, S; Martinelli, G; Mauro, MJ; Muller, MC; Hochhaus, A; Chuah, C; Dufva, IH; Rege-Cambrin, G; Saglio, G; Michallet, M; Labussiere, H; Morisset, S; Hayette, S; Etienne, G; Olavarria, E; Zhou, W; Peter, S; Apperley, JF; Cortes, J,期刊：Blood, 页码：5697-5700 , 文章类型： Article，,卷期：2011年118-20] T315I(+) Philadelphia chromosome-positive leukemias are inherently resistant to all licensed tyrosine kinase inhibitors, and therapeutic options remain limited. We report the outcome of allogeneic stem cell transplantati... 12/15-Lipoxygenase gene knockout severely impairs ischemia-induced angiogenesis due to lack of Rac1 farnesylation [作者：Singh, NK; Kundumani-Sridharan, V; Rao, GN,期刊：Blood, 页码：5701-5712 , 文章类型： Article，,卷期：2011年118-20] To understand the mechanisms by which 15(S)-hydroxyeicosatetraenoic acid (15(S)HETE) activates Rac1 in the induction of angiogenesis, we studied the role of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase and a... Distribution, function, and prognostic value of cytotoxic T lymphocytes in follicular lymphoma: a 3-D tissue-imaging study [作者：Laurent, C; Mueller, S; Do, C; Al-Saati, T; Allart, S; Larocca, LM; Hohaus, S; Duchez, S; Quillet-Mary, A; Laurent, G; Brousset, P; Valitutti, S,期刊：Blood, 页码：5371-5379 , 文章类型： Article，,卷期：2011年118-20] CD8(+) CTLs are thought to play a role in the control of follicular lymphoma (FL). Yet, the link between CTL tissue distribution, activation status, ability to kill FL cells in vivo, and disease progression is still elus... Funding mechanisms and program management at the National Heart, Lung, and Blood Institute: confronting new challenges and exploring new opportunities [作者：Shurin, SB,期刊：Blood, 页码：5380-5382 , 文章类型： Article，,卷期：2011年118-20] Over the past 8 years, the National Institutes of Health (NIH) budget appropriation has lost purchasing power, with erosion of the benefits of the doubling of the budget less than a decade ago. For the first time in 40 y... Mast cell modulation of the vascular and lymphatic endothelium [作者：Kunder, CA; St John, AL; Abraham-, SN,期刊：Blood, 页码：5383-5393 , 文章类型： Review，,卷期：2011年118-20] Mast cells (MCs) promote a wide range of localized and systemic inflammatory responses. Their involvement in immediate as well as chronic inflammatory reactions at both local and distal sites points to an extraordinarily... How I treat pregnancy-related venous thromboembolism [作者：Middeldorp, S,期刊：Blood, 页码：5394-5400 , 文章类型： Article，,卷期：2011年118-20] Venous thromboembolism (VTE) complicates similar to 1 to 2 of 1000 pregnancies, with pulmonary embolism being a leading cause of maternal mortality and deep vein thrombosis an important cause of maternal morbidity, also ... A polymorphism in the leptin gene promoter is associated with anemia in patients with HIV disease [作者：Vanasse, GJ; Jeong, JY; Tate, J; Bathulapalli, H; Anderson, D; Steen, H; Fleming, M; Mattocks, K; Telenti, A; Fellay, J; Justice, AC; Berliner, N,期刊：Blood, 页码：5401-5408 , 文章类型： Article，,卷期：2011年118-20] To study factors associated with anemia and its effect on survival in HIV-infected persons treated with modern combined antiretroviral therapy (cART), we characterized the prevalence of anemia in the Veterans Aging Cohor... Second induction with high-dose cytarabine and mitoxantrone: different impact on pediatric AML patients with t(8;21) and with inv(16) [作者：Creutzig, U; Zimmermann, M; Bourquin, JP; Dworzak, MN; von Neuhoff, C; Sander, A; Schrauder, A; Teigler-Schlegel, A; Stary, J; Corbacioglu, S; Reinhardt, D,期刊：Blood, 页码：5409-5415 , 文章类型： Article，,卷期：2011年118-20] Patients with core binding factor acute myeloid leukemia (CBF-AML) benefit from more intensive chemotherapy, but whether both the t(8;21) and inv(16)/t (16;16) sub-types requires intensification remained to be determined... Mucorales-specific T cells emerge in the course of invasive mucormycosis and may be used as a surrogate diagnostic marker in high-risk patients [作者：Potenza, L; Vallerini, D; Barozzi, P; Riva, G; Forghieri, F; Zanetti, E; Quadrelli, C; Candoni, A; Maertens, J; Rossi, G; Morselli, M; Codeluppi, M; Paolini, A; Maccaferri, M; Del Giovane, C; D'Amico, R; Rumpianesi, F; Pecorari, M; Cavalleri, F; Marasca, R; Narni, F; Luppi, M,期刊：Blood, 页码：5416-5419 , 文章类型： Article，,卷期：2011年118-20] Mucorales-specific T cells were investigated in 28 hematologic patients during the course of their treatment. Three developed proven invasive mucormycosis (IM), 17 had infections of known origin but other than IM, and 8 ... Induction of erythropoiesis using human vascular networks genetically engineered for controlled erythropoietin release [作者：Lin, RZ; Dreyzin, A; Aamodt, K; Li, D; Jaminet, SCS; Dudley, AC; Melero-Martin, JM,期刊：Blood, 页码：5420-5428 , 文章类型： Article，,卷期：2011年118-20] For decades, autologous ex vivo gene therapy has been postulated as a potential alternative to parenteral administration of recombinant proteins. However, achieving effective cellular engraftment of previously retrieved ... The role of Skp2 in hematopoietic stem cell quiescence, pool size, and self-renewal [作者：Wang, J; Han, F; Wu, J; Lee, SW; Chan, CH; Wu, CY; Yang, WL; Gao, Y; Zhang, X; Jeong, YS; Moten, A; Samaniego, F; Huang, P; Liu, QT; Zeng, YX; Lin, HK,期刊：Blood, 页码：5429-5438 , 文章类型： Article，,卷期：2011年118-20] Although the maintenance of HSC quiescence and self-renewal are critical for controlling stem cell pool and transplantation efficiency, the mechanisms by which they are regulated remain largely unknown. Understanding the...