- Differential association of [C-11]PIB and [F-18]FDDNP binding with cognitive impairment
[作者:Tolboom, N; van der Flier, WM; Yaqub, M; Koene, T; Boellaard, R; Windhorst, AD; Scheltens, P; Lammertsma, AA; van Berckel, BNM,期刊:Neurology, 页码:2079-2085 , 文章类型: Article,,卷期:2009年73-24]
- Objective: To evaluate associations of [C-11]Pittsburgh compound B(PIB) and [F-18]FDDNP with impairment in specific cognitive domains over the broader spectrum comprising cognitively normal elderly subjects, patients wit...
- Supratentorial low-grade gliomas in older patients
[作者:Kaloshi, G; Psimaras, D; Mokhtari, K; Dehais, C; Houillier, C; Marie, Y; Laigle-Donadey, F; Taillibert, S; Guillevin, R; Martin-Duverneuil, N; Sanson, M; Hoang-Xuan, K; Delattre, JY,期刊:Neurology, 页码:2093-2098 , 文章类型: Article,,卷期:2009年73-24]
- Background: Low-grade gliomas (LGG) are thought to be very rare in elderly patients (> 60 years) and have not been thoroughly studied.Methods: A series of 62 elderly (>= 60 years of age) LGG patients were identified in a...
- Statin use and neurologic morbidity after coronary artery bypass grafting A cohort study
[作者:Koenig, MA; Grega, MA; Bailey, MM; Pham, LD; Zeger, SL; Baumgartner, WA; McKhann, GM,期刊:Neurology, 页码:2099-2106 , 文章类型: Article,,卷期:2009年73-24]
- Background: Statin use before surgery has been associated with reduced morbidity and mortality after vascular surgery. The effect of preoperative statin use on stroke and encephalopathy after coronary artery bypass graft...
- HLA-DRB1 and month of birth in multiple sclerosis
[作者:Ramagopalan, SV; Link, J; Byrnes, JK; Dyment, DA; Giovannoni, G; Hintzen, RQ; Sundqvist, E; Kockum, I; Smestad, C; Lic, BA; Harbo, HF; Padyukov, L; Alfredsson, L; Olsson, T; Sadovnick, AD; Hillert, J; Ebers, GC,期刊:Neurology, 页码:2107-2111 , 文章类型: Article,,卷期:2009年73-24]
- Background: Multiple sclerosis (MS) displays a month-of-birth effect, with an excess of individuals being born in the spring and a deficit in the winter. This effect was shown to be more pronounced in familial cases of M...
- Road safety in drivers with Parkinson disease
[作者:Uc, EY; Rizzo, M; Johnson, AM; Dastrup, E; Anderson, SW; Dawson, JD,期刊:Neurology, 页码:2112-2119 , 文章类型: Article,,卷期:2009年73-24]
- Objective: To assess road safety and its predictors in drivers with Parkinson disease (PD).Methods: Licensed, active drivers with PD (n = 84; age = 67.3 +/- 7.8, median Hoehn & Yahr stage II) and controls (n = 182; age =...
- A phase 2 multiple ascending dose trial of bapineuzumab in mild to moderate Alzheimer disease
[作者:Salloway, S; Sperling, R; Gilman, S; Fox, NC; Blennow, K; Raskind, M; Sabbagh, M; Honig, LS; Doody, R; van Dyck, CH; Mulnard, R; Barakos, J; Gregg, KM; Liu, E; Lieberburg, I; Schenk, D; Black, R; Grundman, M,期刊:Neurology, 页码:2061-2070 , 文章类型: Article,,卷期:2009年73-24]
- Background: Bapineuzumab, a humanized anti-amyloid-beta (A beta) monoclonal antibody for the potential treatment of Alzheimer disease (AD), was evaluated in a multiple ascending dose, safety, and efficacy study in mild t...
- Association of parental dementia with cognitive and brain MRI measures in middle-aged adults
[作者:Debette, S; Wolf, PA; Beiser, A; Au, R; Himali, JJ; Pikula, A; Auerbach, S; DeCarli, C; Seshadri, S,期刊:Neurology, 页码:2071-2078 , 文章类型: Article,,卷期:2009年73-24]
- Objectives: Studies of autosomal dominant Alzheimer disease (AD) have shown structural and cognitive changes in mutation carriers decades prior to clinical disease. Whether such changes are detectable in offspring of per...
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