- Catalase evolved to concentrate H2O2 at its active site
[作者:Dominguez, L; Sosa-Peinado, A; Hansberg, W,期刊:Archives of Biochemistry and Biophysics , 页码:82-91 , 文章类型: Article,,卷期:2010年500-1]
- Catalase is a homo-tetrameric enzyme that has its heme active site deeply buried inside the protein. Its only substrate, hydrogen peroxide (H2O2), reaches the heme through a 45 A-long channel. Large-subunit catalases, bu...
- An analysis of substrate binding interactions in the heme peroxidase enzymes: A structural perspective
[作者:Gumiero, A; Murphy, EJ; Metcalfe, CL; Moody, PCE; Raven, EL,期刊:Archives of Biochemistry and Biophysics , 页码:13-20 , 文章类型: Review,,卷期:2010年500-1]
- The interactions of heme peroxidase enzymes with their substrates have been studied for many years, but only in the last decade or so has structural information begun to appear. This review looks at crystal structures fo...
- Redox properties of heme peroxidases
[作者:Battistuzzi, G; Bellei, M; Bortolotti, CA; Sola, M,期刊:Archives of Biochemistry and Biophysics , 页码:21-36 , 文章类型: Review,,卷期:2010年500-1]
- Peroxidases are heme enzymes found in bacteria, fungi, plants and animals, which exploit the reduction of hydrogen peroxide to catalyze a number of oxidative reactions, involving a wide variety of organic and inorganic s...
- The dynamic role of distal side residues in heme hydroperoxidase catalysis. Interplay between X-ray crystallography and ab initio MD simulations
[作者:Vidossich, P; Alfonso-Prieto, M; Carpena, X; Fita, I; Loewen, PC; Rovira, C,期刊:Archives of Biochemistry and Biophysics , 页码:37-44 , 文章类型: Review,,卷期:2010年500-1]
- The enzymatic cycle of hydroperoxidases involves the resting Fe(III) state of the enzyme and the high-valent iron intermediates Compound I and Compound II. These states might be characterized by X-ray crystallography and...
- Mechanisms of catalase activity of heme peroxidases
[作者:Vlasits, J; Jakopitsch, C; Bernroitner, M; Zamocky, M; Furtmuller, PG; Obinger, C,期刊:Archives of Biochemistry and Biophysics , 页码:74-81 , 文章类型: Review,,卷期:2010年500-1]
- In the absence of exogenous electron donors monofunctional heme peroxidases can slowly degrade hydrogen peroxide following a mechanism different from monofunctional catalases. This pseudo-catalase cycle involves several ...
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