- Mitochondrial fission proteins Fis1 and Mdv1, but not Dnm1, play a role in maintenance of heteroplasmy in budding yeast
[作者:Bradshaw, E; Yoshida, M; Ling, F,期刊:FEBS Letters, 页码:1245-1251 , 文章类型: Article,,卷期:2012年586-8]
- In budding yeast, the mitochondrial DNA (mtDNA) replication pathway involving the homologous DNA pairing protein Mhr1 promotes mitochondrial allele segregation. Mitochondrial fusion facilitates the recombination-mediated...
- Molecular dynamics simulation of GTPase activity in polymers of the cell division protein FtsZ
[作者:Martin-Garcia, F; Salvarelli, E; Mendieta-Moreno, JI; Vicente, M; Mingorance, J; Mendieta, J; Gomez-Puertas, P,期刊:FEBS Letters, 页码:1236-1239 , 文章类型: Article,,卷期:2012年586-8]
- FtsZ, the prokaryotic ortholog of tubulin, assembles into polymers in the bacterial division ring. The interfaces between monomers contain a GTP molecule, but the relationship between polymerization and GTPase activity i...
- Characterization of nuclear import and export signals determining the subcellular localization of WD repeat-containing protein 42A (WDR42A)
[作者:Wu, FQ; Wang, S; Xing, JJ; Li, ML; Zheng, CF,期刊:FEBS Letters, 页码:1079-1085 , 文章类型: Article,,卷期:2012年586-8]
- WD repeat-containing protein 42A (WDR42A) is a member of the WD40-repeat proteins. Here, we investigated the localization pattern of WDR42A in living cells. By mutational analysis, a nuclear localization signal, 114PRRRV...
- Multiparametric image analysis reveals role of Caveolin1 in endosomal progression rather than internalization of EGFR
[作者:Schmidt-Glenewinkel, H; Reinz, E; Bulashevska, S; Beaudouin, J; Legewie, S; Alonso, A; Eils, R,期刊:FEBS Letters, 页码:1179-1189 , 文章类型: Article,,卷期:2012年586-8]
- Endosomes constitute a central layer in the regulation of growth factor signaling. We applied flow cytometry, confocal microscopy and automated image quantification to define the role of Caveolin1 (Cav1) in epidermal gro...
- Crystal structure of periplasmic catecholate-siderophore binding protein VctP from Vibrio cholerae at 1.7 angstrom resolution
[作者:Liu, XH; Du, Q; Wang, Z; Liu, SH; Li, N; Chen, Y; Zhu, CY; Zhu, DY; Wei, TD; Huang, Y; Xu, SJ; Gu, LC,期刊:FEBS Letters, 页码:1240-1244 , 文章类型: Article,,卷期:2012年586-8]
- VctP, one of the two essential siderophore-binding PBPs from the pathogen Vibrio cholerae, plays an important role in the transport of enterobactin and vibriobactin, which have quite different configurations of iron coor...
- NMR characterization of the interaction between the PUB domain of peptide:N-glycanase and ubiquitin-like domain of HR23
[作者:Kamiya, Y; Uekusa, Y; Sumiyoshi, A; Sasakawa, H; Hirao, T; Suzuki, T; Kato, K,期刊:FEBS Letters, 页码:1141-1146 , 文章类型: Article,,卷期:2012年586-8]
- PUB domains are identified in several proteins functioning in the ubiquitin (Ub)-proteasome system and considered as p97-binding modules. To address the further functional roles of these domains, we herein characterized ...
- Phorbaketal A stimulates osteoblast differentiation through TAZ mediated Runx2 activation
[作者:Byun, MR; Kim, AR; Hwang, JH; Sung, MK; Lee, YK; Hwang, BS; Rho, JR; Hwang, ES; Hong, JH,期刊:FEBS Letters, 页码:1086-1092 , 文章类型: Article,,卷期:2012年586-8]
- Osteoporosis arises from an imbalance between osteoblastic bone formation and osteoclastic bone resorption. In this study, we screened molecules from marine natural products that stimulate osteoblast differentiation. We ...
- Dietary fat ingestion activates beta-endorphin neurons in the hypothalamus
[作者:Matsumura, S; Eguchi, A; Okafuji, Y; Tatsu, S; Mizushige, T; Tsuzuki, S; Inoue, K; Fushiki, T,期刊:FEBS Letters, 页码:1231-1235 , 文章类型: Article,,卷期:2012年586-8]
- The opioid system regulates food choice, consumption, and reinforcement processes, especially for palatable meals such as fatty food. beta-Endorphin is known as an endogenous opioid peptide produced in neurons of the hyp...
- Fibrillogenic propensity of the GroEL apical domain: A Janus-faced minichaperone
[作者:Chen, J; Yagi, H; Sormanni, P; Vendruscolo, M; Makabe, K; Nakamura, T; Goto, Y; Kuwajima, K,期刊:FEBS Letters, 页码:1120-1127 , 文章类型: Article,,卷期:2012年586-8]
- The chaperonin GroEL plays an essential role in promoting protein folding and in protecting against misfolding and aggregation in the cellular environment. In this study, we report that both GroEL and its isolated apical...
- FolX from Pseudomonas aeruginosa is octameric in both crystal and solution
[作者:Gabrielsen, M; Beckham, KSH; Cogdell, RJ; Byron, O; Roe, AJ,期刊:FEBS Letters, 页码:1160-1165 , 文章类型: Article,,卷期:2012年586-8]
- FolX encodes an epimerase that forms one step of the tetrahydrofolate biosynthetic pathway, which is of interest as it is an established target for important drugs. Here we report the crystal structure of FolX from the b...
- Esre: A novel essential non-coding RNA in Escherichia coli
[作者:Chen, ZC; Wang, Y; Li, YR; Li, Y; Fu, N; Ye, J; Zhang, HZ,期刊:FEBS Letters, 页码:1195-1200 , 文章类型: Article,,卷期:2012年586-8]
- YigP gene (GeneID: 948915) locates between ubiquinone biosynthetic genes ubiE and ubiB in Escherichia coli. GeneBank annotates yigP as a putative protein-coding gene. In this study, we found a new essential sRNA gene, es...
- Signaling property study of adhesion G-protein-coupled receptors
[作者:Gupte, J; Swaminath, G; Danao, J; Tian, H; Li, Y; Wu, XL,期刊:FEBS Letters, 页码:1214-1219 , 文章类型: Article,,卷期:2012年586-8]
- Adhesion G-protein-coupled receptors (GPCR) are special members of GPCRs with long N-termini containing multiple domains. We overexpressed our collection of receptors together with G-proteins in mammalian cell lines and ...
- Identification of catechols as histone-lysine demethylase inhibitors
[作者:Nielsen, AL; Kristensen, LH; Stephansen, KB; Kristensen, JBL; Helgstrand, C; Lees, M; Cloos, P; Helin, K; Gajhede, M; Olsen, L,期刊:FEBS Letters, 页码:1190-1194 , 文章类型: Article,,卷期:2012年586-8]
- Identification of inhibitors of histone-lysine demethylase (HDM) enzymes is important because of their involvement in the development of cancer. An ELISA-based assay was developed for identification of inhibitors of the ...
|