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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共7条记录   Drug development and research in New Zealand: policies affecting the industry [作者：Lockhart, MM; Babar, ZUD; Garg, S,期刊：Drug Development Research, 页码：1-10 , 文章类型： Article，,卷期：2012年73-1] Many countries employ a range of policies to support their drug development industry. The support is primarily because of the perceived potential benefits from wealth creation, employment, and international trade related... 3-butyl-6-fluoro-1(3H)-isobenzofuranone (6-F-NBP), a derivative of dl-n-butylphthalide, inhibits glutamate-induced cytotoxicity in PC12 cells [作者：Zhao, N; Ji, MX; Xu, L; Ji, BS,期刊：Drug Development Research, 页码：11-17 , 文章类型： Article，,卷期：2012年73-1] It is widely recognized that glutamate (Glu)-induced cytotoxicity, intracellular calcium overload and the excessive free radical production are key events in the development and progression of ischemic brain injury. dl-3... Carbohydrate-derived Fulvic acid (CHD-FA) inhibits Carrageenan-induced inflammation and enhances wound healing: efficacy and Toxicity study in rats [作者：Sabi, R; Vrey, P; van Rensburg, CEJ,期刊：Drug Development Research, 页码：18-23 , 文章类型： Article，,卷期：2012年73-1] The objectives of this study were to evaluate the safety and anti-inflammatory and wound-healing characteristics of carbohydrate-derived fulvic acid (CHD-FA) in rats. CHD-FA (=100 mg/kg p.o.) effectively reduced carragee... Parallel drug development [作者：Wiklund, SJ,期刊：Drug Development Research, 页码：24-34 , 文章类型： Article，,卷期：2012年73-1] In the pharmaceutical industry, it is common practice to pursue sequentially, within a family of compounds, a number of candidate compounds for further development. This article challenges the sequential tradition, and i... Hetastarch reduces neuronal cell death caused by oxidative stress [作者：Lee, KY; Koh, SH; Kim, S; Park, HH; Lee, YJ,期刊：Drug Development Research, 页码：35-42 , 文章类型： Article，,卷期：2012年73-1] We investigated the effect of hetastarch, used for the treatment of acute ischemic stroke, on neuronal cell damage by oxidative stress, a main pathogenic mechanism in ischemic stroke. Neuronally differentiated PC12 cells... Synergism between tramadol and meloxicam in the formalin test involves both opioidergic and serotonergic pathways [作者：Isiordia-Espinoza, MA; Teran-Rosales, F; Reyes-Garcia, G; Granados-Soto, V,期刊：Drug Development Research, 页码：43-50 , 文章类型： Article，,卷期：2012年73-1] This study was designed to evaluate the antinociceptive interaction of the tramadolmeloxicam combination in different proportions (tramadol + meloxicam in 1:1, 1:3, and 3:1 ratios), as well as the role of nitric oxide, o... Drug development in NZ: can a country be a cluster? [作者：Lockhart, MM; Babar, ZUD; Garg, S,期刊：Drug Development Research, 页码：51-58 , 文章类型： Article，,卷期：2012年73-1] The aims of this research were to assess New Zealand's (NZ) growing drug development industry, and compare it with drug development and biotechnology clusters overseas. This article presents the results of questionnaires...