- Role of Nox2-based NADPH oxidase in bone marrow and progenitor cell function involved in neovascularization induced by hindlimb ischemia
[作者:Urao, N; Inomata, H; Razvi, M; Kim, HW; Wary, K; McKinney, R; Fukai, T; Ushio-Fukai, M,期刊:Circulation Research, 页码:212-220 , 文章类型: Article,,卷期:2008年103-2]
- Bone marrow (BM) is the major reservoir for endothelial progenitor cells (EPCs). Postnatal neovascularization depends on not only angiogenesis but also vasculogenesis, which is mediated through mobilization of EPCs from ...
- Extracellular release of the atheroprotective heat shock protein 27 is mediated by estrogen and competitively inhibits acLDL binding to scavenger receptor-A
[作者:Rayner, K; Chen, YX; McNulty, M; Simard, T; Zhao, X; Wells, DJ; de Belleroche, J; O'Brien, ER,期刊:Circulation Research, 页码:133-141 , 文章类型: Article,,卷期:2008年103-2]
- We recently identified heat shock protein 27 (HSP27) as an estrogen receptor beta (ER beta)-associated protein and noted its role as a biomarker for atherosclerosis. The current study tests the hypothesis that HSP27 is p...
- The del22q11.2 candidate gene Tbx1 controls regional outflow tract identity and coronary artery patterning
[作者:Theveniau-Ruissy, M; Dandonneau, M; Mesbah, K; Ghez, O; Mattei, MG; Miquerol, L; Kelly, RG,期刊:Circulation Research, 页码:142-148 , 文章类型: Article,,卷期:2008年103-2]
- TBX1, encoding a T-box containing transcription factor, is the major candidate gene for del22q11.2 or DiGeorge syndrome, characterized by craniofacial and cardiovascular defects including tetralogy of Fallot and common a...
- Forced alignment of mesenchymal stem cells undergoing cardiomyogenic differentiation affects functional integration with cardiomyocyte cultures
[作者:Pijnappels, DA; Schalij, MJ; Ramkisoensing, AA; van Tuyn, J; de Vries, AAF; van der Laarse, A; Ypey, DL; Atsma, DE,期刊:Circulation Research, 页码:167-176 , 文章类型: Article,,卷期:2008年103-2]
- Alignment of cardiomyocytes (CMCs) contributes to the anisotropic (direction-related) tissue structure of the heart, thereby facilitating efficient electrical and mechanical activation of the ventricles. This study aimed...
- Engineering robust and functional vascular networks in vivo with human adult and cord blood-derived progenitor cells
[作者:Melero-Martin, JM; De Obaldia, ME; Kang, SY; Khan, ZA; Yuan, L; Oettgen, P; Bischoff, J,期刊:Circulation Research, 页码:194-202 , 文章类型: Article,,卷期:2008年103-2]
- The success of therapeutic vascularization and tissue engineering will rely on our ability to create vascular networks using human cells that can be obtained readily, can be expanded safely ex vivo, and can produce robus...
- Neurotrophin p75 receptor (p75(NTR)) promotes endothelial cell apoptosis and inhibits angiogenesis - Implications for diabetes-induced impaired neovascularization in ischemic limb muscles
[作者:Caporali, A; Pani, E; Horrevoets, AJG; Kraenkel, N; Oikawa, A; Sala-Newby, GB; Meloni, M; Cristofaro, B; Graiani, G; Leroyer, AS; Boulanger, CM; Spinetti, G; Yoon, SO; Madeddu, P; Emanueli, C,期刊:Circulation Research, 页码:E15-E26 , 文章类型: Article,,卷期:2008年103-2]
- Diabetes impairs endothelial function and reparative neovascularization. The p75 receptor of neurotrophins (p75(NTR)), which is scarcely present in healthy endothelial cells (ECs), becomes strongly expressed by capillary...
- Redox-sensitive signaling by angiotensin II involves oxidative inactivation and blunted phosphorylation of protein tyrosine phosphatase SHP-2 in vascular smooth muscle cells from SHR
[作者:Tabet, F; Schiffrin, EL; Callera, GE; He, Y; Yao, GY; Ostman, A; Kappert, K; Tonks, NK; Touyz, RM,期刊:Circulation Research, 页码:149-158 , 文章类型: Article,,卷期:2008年103-2]
- Angiotensin II (Ang II) signaling in vascular smooth muscle cells (VSMCs) involves reactive oxygen species (ROS) through unknown mechanisms. We propose that Ang II induces phosphorylation of growth signaling kinases by r...
- Localized alpha 4 integrin phosphorylation directs shear stress-induced endothelial cell alignment
[作者:Goldfinger, LE; Tzima, E; Stockton, R; Kiosses, WB; Kinbara, K; Tkachenko, E; Gutierrez, E; Groisman, A; Nguyen, P; Chien, S; Ginsberg, MH,期刊:Circulation Research, 页码:177-185 , 文章类型: Article,,卷期:2008年103-2]
- Vascular endothelial cells respond to laminar shear stress by aligning in the direction of flow, a process which may contribute to atheroprotection. Here we report that localized alpha 4 integrin phosphorylation is a mec...
- Interleukin-10 from transplanted bone marrow mononuclear cells contributes to cardiac protection after myocardial infarction
[作者:Burchfield, JS; Iwasaki, M; Koyanagi, M; Urbich, C; Rosenthal, N; Zeiher, AM; Dimmeler, S,期刊:Circulation Research, 页码:203-211 , 文章类型: Article,,卷期:2008年103-2]
- Bone marrow mononuclear cells (BM-MNCs) have successfully been used as a therapy for the improvement of left ventricular (LV) function after myocardial infarction (MI). It has been suggested that paracrine factors from B...
- Enhanced cellular uptake of remnant high-density lipoprotein particles - A mechanism for high-density lipoprotein lowering in insulin resistance and hypertriglyceridemia
[作者:Xiao, CT; Watanabe, T; Zhang, Y; Trigatti, B; Szeto, L; Connelly, PW; Marcovina, S; Vaisar, T; Heinecke, JW; Lewis, GF,期刊:Circulation Research, 页码:159-166 , 文章类型: Article,,卷期:2008年103-2]
- A low level of high-density lipoprotein (HDL) cholesterol is characteristic of insulin resistance and hypertriglyceridemia and likely contributes to the increased risk of cardiovascular disease associated with these cond...
|