- Protein kinase A-mediated phosphorylation of cMyBP-C increases proximity of myosin heads to actin in resting myocardium
[作者：Colson, BA; Bekyarova, T; Locher, MR; Fitzsimons, DP; Irving, TC; Moss, RL,期刊：Circulation Research, 页码：244-251 , 文章类型： Article，,卷期：2008年103-3]
- Protein kinase A-mediated (PKA) phosphorylation of cardiac myosin binding protein C (cMyBP-C) accelerates the kinetics of cross-bridge cycling and may relieve the tether-like constraint of myosin heads imposed by cMyBP-C...
- Reactive oxygen species-induced activation of p90 ribosomal S6 kinase prolongs cardiac repolarization through inhibiting outward K+ channel activity
[作者：Lu, Z; Abe, JI; Taunton, J; Lu, Y; Shishido, T; McClain, C; Yan, C; Xu, SP; Spangenberg, TM; Xu, HD,期刊：Circulation Research, 页码：269-278 , 文章类型： Article，,卷期：2008年103-3]
- p90 ribosomal S6 kinase (p90RSK) is activated in cardiomyopathies caused by conditions such as ischemia/reperfusion injury and diabetes mellitus in which prolongation of cardiac repolarization and frequent arrhythmias ar...
- Protein kinase D is a key regulator of cardiomyocyte lipoprotein lipase secretion after diabetes
[作者：Kim, MS; Wang, F; Puthanveetil, P; Kewalramani, G; Hosseini-Beheshti, E; Ng, N; Wang, Y; Kumar, U; Innis, S; Proud, CG; Abrahani, A; Rodrigues, B,期刊：Circulation Research, 页码：252-260 , 文章类型： Article，,卷期：2008年103-3]
- The diabetic heart switches to exclusively using fatty acid ( FA) for energy supply and does so by multiple mechanisms including hydrolysis of lipoproteins by lipoprotein lipase (LPL) positioned at the vascular lumen. We...
- Vascular endothelial growth factor receptor-1 regulates postnatal angiogenesis through inhibition of the excessive activation of Akt
[作者：Nishi, JI; Minamino, T; Miyauchi, H; Nojima, A; Tateno, K; Okada, S; Orimo, M; Moriya, J; Fong, GH; Sunagawa, K; Shibuya, M; Komuro, I,期刊：Circulation Research, 页码：261-268 , 文章类型： Article，,卷期：2008年103-3]
- Vascular endothelial growth factor ( VEGF) binds both VEGF receptor-1 (VEGFR-1) and VEGF receptor-2 (VEGFR-2). Activation of VEGFR-2 is thought to play a major role in the regulation of endothelial function by VEGF. Rece...
- Unexpected structural and functional consequences of the R33Q homozygous mutation in cardiac calsequestrin - A complex arrhythmogenic cascade in a knock in mouse model
[作者：Rizzi, N; Liu, N; Napolitano, C; Nori, A; Turcato, F; Colombi, B; Bicciato, S; Arcelli, D; Spedito, A; Scelsi, M; Villani, L; Esposito, G; Boncompagni, S; Protasi, F; Volpe, P; Priori, SG,期刊：Circulation Research, 页码：298-306 , 文章类型： Article，,卷期：2008年103-3]
- Catecholaminergic polymorphic ventricular tachycardia (CPVT) is an inherited arrhythmogenic disorder characterized by life threatening arrhythmias elicited by physical and emotional stress in young individuals. The reces...
- Glycogen synthase kinase-3 inactivation is not required for ischemic preconditioning or postconditioning in the mouse
[作者：Nishino, Y; Webb, IG; Davidson, SM; Ahmed, AI; Clark, JE; Jacquet, S; Shah, AM; Miura, T; Yellon, DM; Avkiran, M; Marber, MS,期刊：Circulation Research, 页码：307-314 , 文章类型： Article，,卷期：2008年103-3]
- The inactivation of glycogen synthase kinase-3 beta (GSK-3 beta) is proposed as the event integrating protective pathways initiated by preconditioning and other interventions. The inactivation of GSK-3 is thought to decr...
- Endothelial cells provide feedback control for vascular remodeling through a mechanosensitive autocrine TGF-beta signaling pathway
[作者：Baker, AB; Ettenson, DS; Jonas, M; Nugent, MA; Iozzo, RV; Edelman, ER,期刊：Circulation Research, 页码：289-297 , 文章类型： Article，,卷期：2008年103-3]
- Mechanical forces are potent modulators of the growth and hypertrophy of vascular cells. We examined the molecular mechanisms through which mechanical force and hypertension modulate endothelial cell regulation of vascul...
- Role of sphingosine-1-phosphate phosphohydrolase 1 in the regulation of resistance artery tone
[作者：Peter, BF; Lidington, D; Harada, A; Bolz, HJ; Vogel, L; Heximer, S; Spiegel, S; Pohl, U; Bolz, SS,期刊：Circulation Research, 页码：315-324 , 文章类型： Article，,卷期：2008年103-3]
- Sphingosine-1-phosphate (S1P), which mediates pleiotropic actions within the vascular system, is a prominent regulator of microvascular tone. By virtue of its S1P-degrading function, we hypothesized that S1P-phosphohydro...
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