- Connexin40 Imparts Conduction Heterogeneity to Atrial Tissue
[作者：Leaf, DE; Feig, JE; Vasquez, C; Riva, PL; Yu, C; Lader, JM; Kontogeorgis, A; Baron, EL; Peters, NS; Fisher, EA; Gutstein, DE; Morley, GE,期刊：Circulation Research, 页码：1001-U201 , 文章类型： Article，,卷期：2008年103-9]
- Impulse propagation in cardiac tissue is a complex process in which intercellular coupling through gap junction channels is a critical component. Connexin40 (Cx40) is an abundant gap junction protein that is expressed in...
- Disruption of Sarcolemmal ATP-Sensitive Potassium Channel Activity Impairs the Cardiac Response to Systolic Overload
[作者：Hu, XL; Xu, X; Huang, YM; Fassett, J; Flagg, TP; Zhang, Y; Nichols, CG; Bache, RJ; Chen, YJ,期刊：Circulation Research, 页码：1009-U222 , 文章类型： Article，,卷期：2008年103-9]
- Sarcolemmal ATP-sensitive potassium channels (K-ATP) act as metabolic sensors that facilitate adaptation of the left ventricle to changes in energy requirements. This study examined the mechanism by which K-ATP dysfuncti...
- Upstream Stimulatory Factor Is Required for Human Angiotensinogen Expression and Differential Regulation by the A-20C Polymorphism
[作者：Dickson, ME; Tian, X; Liu, XB; Davis, DR; Sigmund, CD,期刊：Circulation Research, 页码：940-U83 , 文章类型： Article，,卷期：2008年103-9]
- Among naturally occurring polymorphisms in the 5' flanking region of the human angiotensinogen (AGT) gene, the -20 and -217 polymorphisms have the strongest effects on AGT regulation in AGT-expressing cells derived from ...
- Overexpression of Vascular Endothelial Growth Factor-B in Mouse Heart Alters Cardiac Lipid Metabolism and Induces Myocardial Hypertrophy
[作者：Karpanen, T; Bry, M; Ollila, HM; Seppanen-Laakso, T; Liimatta, E; Leskinen, H; Kivela, R; Helkamaa, T; Merentie, M; Jeltsch, M; Paavonen, K; Andersson, LC; Mervaala, E; Hassinen, IE; Yla-Herttuala, S; Oresic, M; Alitalo, K,期刊：Circulation Research, 页码：1018-U247 , 文章类型： Article，,卷期：2008年103-9]
- Vascular endothelial growth factor (VEGF)-B is poorly angiogenic but prominently expressed in metabolically highly active tissues, including the heart. We produced mice expressing a cardiac-specific VEGF-B transgene via ...
- Scleraxis Is Required for Cell Lineage Differentiation and Extracellular Matrix Remodeling During Murine Heart Valve Formation In Vivo
[作者：Levay, AK; Peacock, JD; Lu, YH; Koch, M; Hinton, RB; Kadler, KE; Lincoln, J,期刊：Circulation Research, 页码：948-U100 , 文章类型： Article，,卷期：2008年103-9]
- Heart valve structures, derived from mesenchyme precursor cells, are composed of differentiated cell types and extracellular matrix arranged to facilitate valve function. Scleraxis (scx) is a transcription factor require...
- Mechanisms Underlying Erythrocyte and Endothelial Nitrite Reduction to Nitric Oxide in Hypoxia Role for Xanthine Oxidoreductase and Endothelial Nitric Oxide Synthase
[作者：Webb, AJ; Milsom, AB; Rathod, KS; Chu, WL; Qureshi, S; Lovell, MJ; Lecomte, FMJ; Perrett, D; Raimondo, C; Khoshbin, E; Ahmed, Z; Uppal, R; Benjamin, N; Hobbs, AJ; Ahluwalia, A,期刊：Circulation Research, 页码：957-U114 , 文章类型： Article，,卷期：2008年103-9]
- Reduction of nitrite (NO2-) provides a major source of nitric oxide (NO) in the circulation, especially in hypoxemic conditions. Our previous studies suggest that xanthine oxidoreductase (XOR) is an important nitrite red...
- Isoprostanes Inhibit Vascular Endothelial Growth Factor-Induced Endothelial Cell Migration, Tube Formation, and Cardiac Vessel Sprouting In Vitro, As Well As Angiogenesis In Vivo via Activation of the Thromboxane A(2) Receptor A Potential Link Between Oxidative Stress and Impaired Angiogenesis
[作者：Benndorf, RA; Schwedhelm, E; Gnann, A; Taheri, R; Kom, G; Didie, M; Steenpass, A; Ergun, S; Boger, RH,期刊：Circulation Research, 页码：1037-U302 , 文章类型： Article，,卷期：2008年103-9]
- Isoprostanes are endogenously formed end products of lipid peroxidation. Furthermore, they are markers of oxidative stress and independent risk markers of coronary heart disease. In patients experiencing coronary heart d...
- CD11c(+) Dendritic Cells Maintain Antigen Processing, Presentation Capabilities, and CD4(+) T-Cell Priming Efficacy Under Hypercholesterolemic Conditions Associated With Atherosclerosis
[作者：Packard, RRS; Maganto-Garcia, E; Gotsman, I; Tabas, I; Libby, P; Lichtman, AH,期刊：Circulation Research, 页码：965-U130 , 文章类型： Article，,卷期：2008年103-9]
- Recent reports suggest dyslipidemia impairs dendritic cell (DC) function and adaptive immunity. This study aimed to characterize the effect of hypercholesterolemia on antigen-presenting cell function of DCs and DC-depend...
- Nuclear alpha 1-Adrenergic Receptors Signal Activated ERK Localization to Caveolae in Adult Cardiac Myocytes
[作者：Wright, CD; Chen, QH; Baye, NL; Huang, Y; Healy, CL; Kasinathan, S; O'Connell, TD,期刊：Circulation Research, 页码：992-1000 , 文章类型： Article，,卷期：2008年103-9]
- We previously identified an alpha 1-AR-ERK (alpha 1A-adrenergic receptor-extracellular signal-regulated kinase) survival signaling pathway in adult cardiac myocytes. Here, we investigated localization of alpha 1-AR subty...
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