- Venom evolution through gene duplications
[作者:Wong, ESW; Belov, K,期刊:Gene, 页码:1-7 , 文章类型: Review,,卷期:2012年496-1]
- Venoms contain highly complex mixtures that typically include hundreds of different components and have evolved independently in a diverse range of animals including platypuses, shrews, snakes, lizards, fishes, echinoder...
- Long non-coding RNA UCA1 regulated cell cycle distribution via CREB through P13-K dependent pathway in bladder carcinoma cells
[作者:Yang, C; Li, X; Wang, Y; Zhao, L; Chen, W,期刊:Gene, 页码:8-16 , 文章类型: Article,,卷期:2012年496-1]
- Long non-coding RNA urothelial carcinoma associated 1 (UCA1) promotes human bladder cancer cell proliferation, but the underlying mechanism remains unknown. After knocking down of UCA1 in BLZ-211 cells, several cell cycl...
- Inactivation of the MSLNL gene encoding mesothelin-like protein during African great ape evolution
[作者:Kim, DW; Jeong, S; Kim, DS; Kim, HS; Seo, SB; Hahn, Y,期刊:Gene, 页码:17-21 , 文章类型: Article,,卷期:2012年496-1]
- Loss of gene function is implicated in the emergence of novel phenotypes during organism evolution. Here, we report the inactivation of the MSLNL gene encoding mesothelin-like protein in African great ape evolution. Huma...
- High frequency of Neuropeptide Y Leu7Pro polymorphism in an Iranian population and its association with coronary artery disease
[作者:Masoudi-Kazemabad, A; Jamialahmadi, K; Moohebati, M; Mojarrad, M; Dehghan-Manshadi, R; Forghanifard, MM; Akhlaghi, S; Ferns, GA; Ghayour-Mobarhan, M,期刊:Gene, 页码:22-27 , 文章类型: Article,,卷期:2012年496-1]
- Objective: Neuropeptide Y (NPY), a 36-amino acid peptide, is widely expressed in the central and peripheral nervous systems as well as in the heart. A relationship has been reported between NPY gene variants and coronary...
- Coexisting role of fasting or feeding and dietary lipids in the control of gene expression of enzymes involved in the synthesis of saturated, monounsaturated and polyunsaturated fatty acids
[作者:Rodriguez-Cruz, M; Gonzalez, RS; Garcia, AMS; Lopez-Alarcon, M,期刊:Gene, 页码:28-36 , 文章类型: Article,,卷期:2012年496-1]
- In the liver, maintaining lipid homeostasis is regulated by physiological and exogenous factors. These lipids are synthesized by Fasn, elongases and desaturases. Interactions in an organism among these factors are quite ...
- Differences in mtDNA whole sequence between Tibetan and Han populations suggesting adaptive selection to high altitude
[作者:Gu, ML; Dong, XQ; Shi, L; Shi, L; Lin, KQ; Huang, XQ; Chu, JY,期刊:Gene, 页码:37-44 , 文章类型: Article,,卷期:2012年496-1]
- We performed a mitochondrial whole-genome comparison study in 40 Tibetan and 50 Han Chinese. All subjects could be classified into 13 haplogroups pertained to the Macrohaplogroup M and N that pitched different quadrants ...
- Identification of ORF sequences and exercise-induced expression change in thoroughbred horse OXCT1 gene
[作者:Nam, GH; Ahn, K; Bae, JH; Cho, BW; Park, KD; Lee, HK; Yang, YM; Kim, TH; Seong, HH; Han, K; Kim, HS,期刊:Gene, 页码:45-48 , 文章类型: Article,,卷期:2012年496-1]
- In the mitochondrial matrix, the OXCT1 gene catalyzes the reversible transfer of coenzyme A from succinyl-CoA to acetoacetate in a reaction related to energy production from ketone bodies. Here, horse OXCT1 gene containi...
- The first mutations in the MYH gene reported in Moroccan colon cancer patients
[作者:Laarabi, FZ; Jaouad, IC; Baert-Desurmont, S; Ouldim, K; Ibrahimi, A; Kanouni, N; Frebourg, T; Sefiani, A,期刊:Gene, 页码:55-58 , 文章类型: Article,,卷期:2012年496-1]
- Background: Biallelic germline mutations in the MYH gene cause MYH-associated polyposis (MAP) disease, an autosomal recessive form of inherited colorectal cancer. People with MAP tend to develop attenuated multiple adeno...
- Cytogenomic characterization of an unexpected 17.6 Mb 9p deletion associated to a 14.8 Mb 20p duplication in a dysmorphic patient with multiple congenital anomalies presenting a normal G-banding karyotype
[作者:Meloni, VDA; Piazzon, FB; Soares, MDD; Takeno, SS; Christofolini, DM; Kulikowski, LD; Brunoni, D; Melaragno, MI,期刊:Gene, 页码:59-62 , 文章类型: Article,,卷期:2012年496-1]
- We describe a female patient with developmental delay, dysmorphic features and multiple congenital anomalies who presented a normal G-banded karyotype at the 550-band resolution. Array and multiplex-ligation probe amplif...
- Association of adiponectin gene functional polymorphisms (-11377C/G and +45T/G) with nonalcoholic fatty liver disease
[作者:Gupta, AC; Misra, R; Sakhuja, P; Singh, Y; Basir, SF; Sarin, SK,期刊:Gene, 页码:63-67 , 文章类型: Article,,卷期:2012年496-1]
- Adiponectin levels are reduced in NAFLD patients and genetic variants of adiponectin have been frequently associated with type 2 diabetes and insulin resistance. To determine the genotypic frequencies of adiponectin func...
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