- Differential effects of non-steroidal anti-inflammatory drugs on mitochondrial dysfunction during oxidative stress
[作者:Lal, N; Kumar, J; Erdahl, WE; Pfeiffer, DR; Gadd, ME; Graff, G; Yanni, JM,期刊:Archives of Biochemistry and Biophysics , 页码:1-8 , 文章类型: Article,,卷期:2009年490-1]
- We investigated the effects of several non-steroidal anti-inflammatory drugs on swelling related properties of mitochondria, with an emphasis on compounds that are marketed and utilized topically in the eye (nepafenac, k...
- Structural studies of the N-terminus of Connexin 32 using H-1 NMR spectroscopy
[作者:Kalmatsky, BD; Bhagan, S; Tang, Q; Bargiello, TA; Dowd, TL,期刊:Archives of Biochemistry and Biophysics , 页码:9-16 , 文章类型: Article,,卷期:2009年490-1]
- The amino terminus of gap junction proteins, connexins, plays a fundamental role in voltage gating and ion permeation. We have previously shown with H-1 NMR that the structure of the N-terminus of a representative connex...
- Changes in islet plasma membrane calcium-ATPase activity and isoform expression induced by insulin resistance
[作者:Alzugaray, ME; Garcia, ME; Del Zotto, HH; Raschia, MA; Palomeque, J; Rossi, JPFC; Gagliardino, JJ; Flores, LE,期刊:Archives of Biochemistry and Biophysics , 页码:17-23 , 文章类型: Article,,卷期:2009年490-1]
- We studied the effect of insulin resistance (IR) induced by administration of a fructose-rich diet (FRD) to normal Wistar rats for 21 days, upon islet plasma membrane calcium ATPases (PMCAs) and insulin secretion. FRD ra...
- Supercomplexes of the mitochondrial electron transport chain decline in the aging rat heart
[作者:Gomez, LA; Monette, JS; Chavez, JD; Maier, CS; Hagen, TM,期刊:Archives of Biochemistry and Biophysics , 页码:30-35 , 文章类型: Article,,卷期:2009年490-1]
- Accumulation of mitochondrial electron transport chain (ETC) defects is a recognized hallmark of the age-associated decline in cardiac bioenergetics; however, the molecular events involved are only poorly understood. In ...
- Interactions across the interface contribute the stability of homodimeric 3 alpha-hydroxysteroid dehydrogenase/carbonyl reductase
[作者:Hwang, CC; Hsu, CN; Huang, TJ; Chiou, SJ; Hong, YR,期刊:Archives of Biochemistry and Biophysics , 页码:36-41 , 文章类型: Article,,卷期:2009年490-1]
- The dimerization of 3x-hydroxysteroid dehydrogenase/carbonyl reductase was studied by interrupting the salt bridge interactions between D249 and 8767 in the dimeric interface. Substitution of alanine, lysine and serine f...
- EPR spectroscopy and electrospray ionization mass spectrometry reveal distinctive features of the iron site in leukocyte 12-lipoxygenase
[作者:Rapp, J; Xu, S; Sharp, AM; Griffith, WP; Kim, YW; Funk, MO,期刊:Archives of Biochemistry and Biophysics , 页码:50-56 , 文章类型: Article,,卷期:2009年490-1]
- The procedure for the expression and purification of recombinant porcine leukocyte 12-lipoxygenase using Escherichia coli [K.M. Richards, L.J. Marnett, Biochemistry 36 (1997) 6692-6699] was updated to make it possible to...
- Concerted bifunctionality of the dCTP deaminase-dUTPase from Methanocaldococcus jannaschii: A structural and pre-steady state kinetic analysis
[作者:Siggaard, JHB; Johansson, E; Vognsen, T; Helt, SS; Harris, P; Larsen, S; Willemoes, M,期刊:Archives of Biochemistry and Biophysics , 页码:42-49 , 文章类型: Article,,卷期:2009年490-1]
- Two mutant dCTP deaminase-dUTPases from Methanocaldococcus jannaschii were crystallised and the crystal structures were solved: E145A in complex with the substrate analogue alpha,beta-imido-dUTP and E145Q in complex with...
- Oridonin induces G(2)/M arrest and apoptosis via activating ERK-p53 apoptotic pathway and inhibiting PTK-Ras-Raf-JNK survival pathway in murine fibrosarcoma L929 cells
[作者:Cheng, Y; Qiu, F; Ye, YC; Tashiro, S; Onodera, S; Ikejima, T,期刊:Archives of Biochemistry and Biophysics , 页码:70-75 , 文章类型: Article,,卷期:2009年490-1]
- Oridonin was reported to induce L929 cell apoptosis via ROS-mediated mitochondrial and ERK pathways: however, the precise mechanisms by which oridonin induces cell death remain unclear. Herein. we found that oridonin tre...
- Characterization of a blue-copper protein, auracyanin, of the filamentous anoxygenic phototrophic bacterium Roseiflexus castenholzii
[作者:Tsukatani, Y; Nakayama, N; Shimada, K; Mino, H; Itoh, S; Matsuura, K; Hanada, S; Nagashima, KVP,期刊:Archives of Biochemistry and Biophysics , 页码:57-62 , 文章类型: Article,,卷期:2009年490-1]
- A blue-copper protein auracyanin of the filamentous anoxygenic phototroph Roseiflexus castenholzii was purified and characterized. Genomic sequence analysis showed that R. castenholzii has only one auracyanin, whereas Ch...
- Aggravation of ischemia-reperfusion-triggered acute renal failure in xCT-deficient mice
[作者:Shibasaki, T; Iuchi, Y; Okada, F; Kuwata, K; Yamanobe, T; Bannai, S; Tomita, Y; Sato, H; Fujii, J,期刊:Archives of Biochemistry and Biophysics , 页码:63-69 , 文章类型: Article,,卷期:2009年490-1]
- This study examined the question of whether deficiency of xCT, a cystine-transporter gene, exacerbates ischemia-reperfusion-induced acute renal failure (ARF). Two weeks after the right nephrectomy of male mice at 16-18 w...
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