- Tropoelastin as a thermodynamically unfolded premolten globule protein: The effect of trimethylamine N-oxide on structure and coacervation
[作者:Dyksterhuis, LB; Carter, EA; Mithieux, SM; Weiss, AS,期刊:Archives of Biochemistry and Biophysics , 页码:79-84 , 文章类型: Article,,卷期:2009年487-2]
- Tropoelastin is the monomer building block of the biopolymer elastin, which is responsible for elasticity in arteries, lung and skin. Previous studies have shown that, in contrast to predictions made based on primary seq...
- Demonstration of microtubule-like structures formed with (-)-rhazinilam from purified tubulin outside of cells and a simple tubulin-based assay for evaluation of analog activity
[作者:Edler, MC; Yang, GL; Jung, MK; Bai, RL; Bornmann, WG; Hamel, E,期刊:Archives of Biochemistry and Biophysics , 页码:98-104 , 文章类型: Article,,卷期:2009年487-2]
- (-)-Rhazinilam was spontaneously generated from a natural product during isolation. In cultured cells, it causes microtubule bundle formation, like those caused by paclitaxel. With tubulin, (-)-rhazinilam causes formatio...
- A study of human furin specificity using synthetic peptides derived from natural substrates, and effects of potassium ions
[作者:Izidoro, MA; Gouvea, IE; Santos, JAN; Assis, DM; Oliveira, V; Judice, WAS; Juliano, MA; Lindberg, I; Juliano, L,期刊:Archives of Biochemistry and Biophysics , 页码:105-114 , 文章类型: Article,,卷期:2009年487-2]
- We explored furin Substrate requirements in addition to the motif R-X-K/R-R using synthetic fluorescent resonance energy transfer (FRET) decapeptides. These decapeptides were derived from furin cleavage sites in viral co...
- Structural, functional and unfolding characteristics of glutathione S-transferase of Plasmodium vivax
[作者:Tripathi, T; Na, BK; Sohn, WM; Becker, K; Bhakuni, V,期刊:Archives of Biochemistry and Biophysics , 页码:115-122 , 文章类型: Article,,卷期:2009年487-2]
- Glutathione S-transferases (GSTs) of Plasmodium parasites are potential targets for antimalarial drug and vaccine development. We investigated the equilibrium unfolding, functional activity regulation and stability chara...
- Role of protein kinase C in NADPH oxidase derived O-2(center dot-)-mediated regulation of K-V-LVOCC axis under U46619 induced increase in [Ca2+](i) in pulmonary smooth muscle cells
[作者:Chakraborti, S; Chowdhury, A; Kar, P; Das, P; Shaikh, S; Roy, S; Chakraborti, T,期刊:Archives of Biochemistry and Biophysics , 页码:123-130 , 文章类型: Article,,卷期:2009年487-2]
- Treatment of bovine pulmonary smooth muscle cells with the TxA(2) mimetic, U46619 stimulated [Ca2+](i), which was inhibited upon pretreatment with apocynin (NADPH oxidase inhibitor). Pretreatment with cromakalim (K-V cha...
- Transferrin secretory pathways in rat parotid acinar cells
[作者:Nashida, T; Yoshie, S; Imai, A; Shimomura, H,期刊:Archives of Biochemistry and Biophysics , 页码:131-138 , 文章类型: Article,,卷期:2009年487-2]
- Transferrin is the major iron transporter in blood plasma, and is also found, at lower concentrations, in saliva. We studied the synthesis and secretion of transferrin in rat parotid acinar cells in order to elucidate it...
- 15-Hydroxyprostaglandin dehydrogenase (15-PGDH) is up-regulated by flurbiprofen and other non-steroidal anti-inflammatory drugs in human colon cancer HT29 cells
[作者:Chi, XL; Freeman, BM; Tong, M; Zhao, YH; Tai, HH,期刊:Archives of Biochemistry and Biophysics , 页码:139-145 , 文章类型: Article,,卷期:2009年487-2]
- Non-steroidal anti-inflammatory drugs (NSAIDs) are known to inhibit prostaglandin synthetic enzyme, cyclooxygenases (COXs), as well as to exhibit anti-tumor activity although at much higher concentrations. 15-Hydroxypros...
- Exogenous vs. endogenous gamma-glutamyltransferase activity: Implications for the specific determination of S-nitrosoglutathione in biological samples
[作者:Bramanti, E; Angeli, V; Franzini, M; Vecoli, C; Baldassini, R; Paolicchi, A; Barsacchi, R; Pompella, A,期刊:Archives of Biochemistry and Biophysics , 页码:146-152 , 文章类型: Article,,卷期:2009年487-2]
- The determination of S-nitrosoglutathione (GSNO) levels in biological fluids is controversial, partly due to the laborious sample handling and multiple pretreatment steps required by current techniques. GSNO decompositio...
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