- New insights into the mechanisms of hematopoietic cell transformation by activated receptor tyrosine kinases
[作者：Toffalini, F; Demoulin, JB,期刊：Blood, 页码：2429-2437 , 文章类型： Review，,卷期：2010年116-14]
- A large number of alterations in genes encoding receptor tyrosine kinase (RTK), namely FLT3, c-KIT, platelet-derived growth factor (PDGF) receptors, fibroblast growth factor (FGF) receptors, and the anaplastic large cell...
- Donor selection for natural killer cell receptor genes leads to superior survival after unrelated transplantation for acute myelogenous leukemia
[作者：Cooley, S; Weisdorf, DJ; Guethlein, LA; Klein, JP; Wang, T; Le, CT; Marsh, SGE; Geraghty, D; Spellman, S; Haagenson, MD; Ladner, M; Trachtenberg, E; Parham, P; Miller, JS,期刊：Blood, 页码：2411-2419 , 文章类型： Article，,卷期：2010年116-14]
- Killer-cell immunoglobulin-like receptor (KIR) genes form a diverse, immunogenetic system. Group A and B KIR haplotypes have distinctive centromeric (Cen) and telomeric (Tel) gene-content motifs. Aiming to develop a dono...
- Shortcomings in the clinical evaluation of new drugs: acute myeloid leukemia as paradigm
[作者：Walter, RB; Appelbaum, FR; Tallman, MS; Weiss, NS; Larson, RA; Estey, EH,期刊：Blood, 页码：2420-2428 , 文章类型： Article，,卷期：2010年116-14]
- Drugs introduced over the past 25 years have benefitted many patients with acute myeloid leukemia (AML) and provided cure for some. Still, AML remains difficult to treat, and most patients will eventually die from their ...
- Assessment of disease severity and outcome in patients with systemic light-chain amyloidosis by the high-sensitivity troponin T assay
[作者：Kristen, AV; Giannitsis, E; Lehrke, S; Hegenbart, U; Konstandin, M; Lindenmaier, D; Merkle, C; Hardt, S; Schnabel, PA; Rocken, C; Schonland, SO; Ho, AD; Dengler, TJ; Katus, HA,期刊：Blood, 页码：2455-2461 , 文章类型： Article，,卷期：2010年116-14]
- Cardiac biomarkers provide prognostic information in light-chain amyloidosis (AL). Thus, a novel high-sensitivity cardiac troponin T (hs-TnT) assay may improve risk stratification. hs-TnT was assessed in 163 patients. Bl...
- Allogeneic stem cell transplantation provides durable disease control in poor-risk chronic lymphocytic leukemia: long-term clinical and MRD results of the German CLL Study Group CLL3X trial
[作者：Dreger, P; Dohner, H; Ritgen, M; Bottcher, S; Busch, R; Dietrich, S; Bunjes, D; Cohen, S; Schubert, J; Hegenbart, U; Beelen, D; Zeis, M; Stadler, M; Hasenkamp, J; Uharek, L; Scheid, C; Humpe, A; Zenz, T; Winkler, D; Hallek, M; Kneba, M; Schmitz, N; Stilgenbauer, S,期刊：Blood, 页码：2438-2447 , 文章类型： Article，,卷期：2010年116-14]
- The purpose of this prospective multicenter phase 2 trial was to investigate the long-term outcome of reduced-intensity conditioning allogeneic stem cell transplantation (alloSCT) in patients with poor-risk chronic lymph...
- Iron chelation therapy with deferasirox in patients with aplastic anemia: a subgroup analysis of 116 patients from the EPIC trial
[作者：Lee, JW; Yoon, SS; Shen, ZXA; Ganser, A; Hsu, HC; Habr, D; Domokos, G; Roubert, B; Porter, JB,期刊：Blood, 页码：2448-2454 , 文章类型： Article，,卷期：2010年116-14]
- The prospective 1-year Evaluation of Patients' Iron Chelation with Exjade (EPIC) study enrolled a large cohort of 116 patients with aplastic anemia; the present analyses evaluated the efficacy and safety of deferasirox i...
- STAT3 controls myeloid progenitor growth during emergency granulopoiesis
[作者：Zhang, HY; Nguyen-Jackson, H; Panopoulos, AD; Li, HYS; Murray, PJ; Watowich, SS,期刊：Blood, 页码：2462-2471 , 文章类型： Article，,卷期：2010年116-14]
- Granulocyte colony-stimulating factor (G-CSF) mediates "emergency" granulopoiesis during infection, a process that is mimicked by clinical G-CSF use, yet we understand little about the intracellular signaling cascades th...
- Sustained IL-4 exposure leads to a novel pathway for hemophagocytosis, inflammation, and tissue macrophage accumulation
[作者：Milner, JD; Orekov, T; Ward, JM; Cheng, L; Torres-Velez, F; Junttila, I; Sun, GP; Buller, M; Morris, SC; Finkelman, FD; Paul, WE,期刊：Blood, 页码：2476-2483 , 文章类型： Article，,卷期：2010年116-14]
- Erythrophagocytosis and inflammation from activated macrophages occur in distinct clinical scenarios. The presence of CD8(+) T cells and interferon-gamma (IFN-gamma) production is required to induce disease in mouse mode...
- Program death-1 signaling and regulatory T cells collaborate to resist the function of adoptively transferred cytotoxic T lymphocytes in advanced acute myeloid leukemia
[作者：Zhou, Q; Munger, ME; Highfill, SL; Tolar, J; Weigel, BJ; Riddle, M; Sharpe, AH; Vallera, DA; Azuma, M; Levine, BL; June, CH; Murphy, WJ; Munn, DH; Blazar, BR,期刊：Blood, 页码：2484-2493 , 文章类型： Article，,卷期：2010年116-14]
- Tumor-induced immune defects can weaken host immune response and permit tumor cell growth. In a systemic model of murine acute myeloid leukemia (AML), tumor progression resulted in increased regulatory T cells (Treg) and...
- Thymic and peripheral microenvironments differentially mediate development and maturation of iNKT cells by IL-15 transpresentation
[作者：Castillo, EF; Acero, LF; Stonier, SW; Zhou, DP; Schluns, KS,期刊：Blood, 页码：2494-2503 , 文章类型： Article，,卷期：2010年116-14]
- Invariant NKT (iNKT) cells are an innate type of T cells, which respond rapidly on activation. iNKT cells acquire these innate-like abilities during development; however, the signals driving development and functional ma...
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