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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共17条记录   Microbubble ultrasound-guided targeted delivery to tumors [作者：Park, K,期刊：Journal of controlled release, 页码：167-167 , 文章类型： Editorial Material，,卷期：2012年157-2] Albumin-based nanoparticles as potential controlled release drug delivery systems [作者：Elzoghby, AO; Samy, WM; Elgindy, NA,期刊：Journal of controlled release, 页码：168-182 , 文章类型： Review，,卷期：2012年157-2] Albumin, a versatile protein carrier for drug delivery, has been shown to be nontoxic, non-immunogenic, biocompatible and biodegradable. Therefore, it is ideal material to fabricate nanoparticles for drug delivery. Album... Non-viral gene therapy for neurological diseases, with an emphasis on targeted gene delivery [作者：Rogers, ML; Rush, RA,期刊：Journal of controlled release, 页码：183-189 , 文章类型： Review，,卷期：2012年157-2] Non-viral gene therapy systems are considered safer than viral delivery. This article reviews recent research describing novel, non-viral gene delivery to the central nervous system, with a special emphasis on receptor m... In vivo antitumor effect of cromolyn in PEGylated liposomes for pancreatic cancer [作者：Kim, CE; Lim, SK; Kim, JS,期刊：Journal of controlled release, 页码：190-195 , 文章类型： Article，,卷期：2012年157-2] A PEGylated liposomal formulation of cromolyn, composed of dipalmitoylphosphatidylcholine (DPPC), dimyristoylphosphatidylcholine (DMPC), distearoylphosphatidylcholine (DSPC) and 1,2-distearoyl-sn-glycero-3-phospho-ethano... Improved in vivo delivery of m-THPC via pegylated liposomes for use in photodynamic therapy [作者：Bovis, MJ; Woodhams, JH; Loizidou, M; Scheglmann, D; Bown, SG; MacRobert, AJ,期刊：Journal of controlled release, 页码：196-205 , 文章类型： Article，,卷期：2012年157-2] Pegylated liposomal nanocarriers have been developed with the aim of achieving improved uptake of the clinical PDT photosensitiser, m-THPC, into target tissues through increased circulation time and bioavailability. This... Cubic phase-forming dry powders for controlled drug delivery on mucosal surfaces [作者：Moebus, K; Siepmann, J; Bodmeier, R,期刊：Journal of controlled release, 页码：206-215 , 文章类型： Article，,卷期：2012年157-2] The purpose of this study was to prepare and physicochemically characterize protein-loaded, glycerol monooleate (GMO)-based dry powder systems, which can be used for the controlled mucosal delivery of macromolecules (e.g... Improvement of CXCR4 tracer specificity for PET imaging [作者：Jacobson, O; Weiss, ID; Szajek, LP; Niu, G; Ma, Y; Kiesewetter, DO; Peled, A; Eden, HS; Farber, JM; Chen, XY,期刊：Journal of controlled release, 页码：216-223 , 文章类型： Article，,卷期：2012年157-2] Tumors expressing the chemokine receptor CXCR4 have been reported to be more aggressive and to produce more metastatic seeding in specific organs, such as the bone marrow. However, evaluation of tumors for CXCR4 expressi... Polyplex-microbubble hybrids for ultrasound-guided plasmid DNA delivery to solid tumors [作者：Sirsi, SR; Hernandez, SL; Zielinski, L; Blomback, H; Koubaa, A; Synder, M; Homma, S; Kandel, JJ; Yamashiro, DJ; Borden, MA,期刊：Journal of controlled release, 页码：224-234 , 文章类型： Article，,卷期：2012年157-2] Microbubble ultrasound contrast agents are being developed as image-guided gene carriers for targeted delivery in vivo. In this study, novel polyplex-microbubbles were synthesized, characterized and evaluated for systemi... Ultrasound-induced cavitation enhances the delivery and therapeutic efficacy of an oncolytic virus in an in vitro model [作者：Bazan-Peregrino, M; Arvanitis, CD; Rifai, B; Seymour, LW; Coussios, CC,期刊：Journal of controlled release, 页码：235-242 , 文章类型： Article，,卷期：2012年157-2] We investigated whether ultrasound-induced cavitation at 0.5 MHz could improve the extravasation and distribution of a potent breast cancer-selective oncolytic adenovirus, AdEHE2F-Luc, to tumour regions that are remote f... Efficient GLP-1 gene delivery using two-step transcription amplification plasmid system with a secretion signal peptide and arginine-grafted bioreducible polymer [作者：Kim, TI; Lee, M; Kim, SW,期刊：Journal of controlled release, 页码：243-248 , 文章类型： Article，,卷期：2012年157-2] Glucagon-like peptide (GLP-1) encoding dual plasmid (pDNA) system (TSTA (SP-GLP-1)) which is composed of p beta-Gal4-p65 and pUAS-SP-GLP-1 was constructed to improve the production and secretion of expressed GLP-1 by com... Addition of ascorbic acid to the extracellular environment activates lipoplexes of a ferrocenyl lipid and promotes cell transfection [作者：Aytar, BS; Muller, JPE; Golan, S; Hata, S; Takahashi, H; Kondo, Y; Talmon, Y; Abbott, NL; Lynn, DM,期刊：Journal of controlled release, 页码：249-259 , 文章类型： Article，,卷期：2012年157-2] The level of cell transfection mediated by lipoplexes formed using the ferrocenyl lipid bis(11-ferrocenylundecyl) dimethylammonium bromide (BFDMA) depends strongly on the oxidation state of the two ferrocenyl groups of t... Structural rearrangements and chemical modifications in known cell penetrating peptide strongly enhance DNA delivery efficiency [作者：Mann, RA; Khanduri, R; Naik, RJ; Ganguli, M,期刊：Journal of controlled release, 页码：260-271 , 文章类型： Article，,卷期：2012年157-2] Amphipathic peptides with unusual cellular translocation properties have been used as carriers of different biomolecules. However, the parameters which control the delivery efficiency of a particular cargo by a peptide a... Efficient skin permeation of soluble proteins via flexible and functional nano-carrier [作者：Choi, WI; Lee, JH; Kim, JY; Kim, JC; Kim, YH; Tae, G,期刊：Journal of controlled release, 页码：272-278 , 文章类型： Article，,卷期：2012年157-2] In spite of several intrinsic and distinct advantages, a topical and transdermal administration of drugs has been limited mainly due to very low permeability of drugs across skin. Especially, it is generally regarded tha... Nanoparticle delivery of a peptide targeting EGFR signaling [作者：Kim, SK; Huang, L,期刊：Journal of controlled release, 页码：279-286 , 文章类型： Article，,卷期：2012年157-2] EGFR serves as an important therapeutic target because of its over-expression in many cancers. In this study, we investigated a peptide-based therapy aimed at blocking intracellular protein-protein interactions during EG... EGFR-targeted stearoyl gemcitabine nanoparticles show enhanced anti-tumor activity [作者：Sandoval, MA; Sloat, BR; Lansakara, DSP; Kumar, A; Rodriguez, BL; Kiguchi, K; DiGiovanni, J; Cui, ZR,期刊：Journal of controlled release, 页码：287-296 , 文章类型： Article，,卷期：2012年157-2] Previously, it was shown that a novel 4-(N)-stearoyl gemcitabine nanoparticle formulation was more effective than gemcitabine hydrochloride in controlling the growth of model mouse or human tumors pre-established in mice... Biophysical properties of chitosan/siRNA polyplexes: Profiling the polymer/siRNA interactions and bioactivity [作者：Holzerny, P; Ajdini, B; Heusermann, W; Bruno, K; Schuleit, M; Meinel, L; Keller, M,期刊：Journal of controlled release, 页码：297-304 , 文章类型： Article，,卷期：2012年157-2] Chitosans are naturally occurring polymers widely used in life science to mediate intracellular uptake of nucleic acids such as siRNA. Four chitosans of fungal origin (Agaricus bisporus; molecular weights MW = 44, 63, 93...