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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共19条记录   Single-cell force spectroscopy [作者：Helenius, J; Heisenberg, CP; Gaub, HE; Muller, DJ,期刊：Journal of cell science, 页码：1785-1791 , 文章类型： Article，,卷期：2008年121-11] The controlled adhesion of cells to each other and to the extracellular matrix is crucial for tissue development and maintenance. Numerous assays have been developed to quantify cell adhesion. Among these, the use of ato... Plasma membrane recruitment of dephosphorylated beta-catenin upon activation of the Wnt pathway [作者：Hendriksen, J; Jansen, M; Brown, CM; van der Velde, H; van Ham, M; Galjart, N; Offerhaus, GJ; Fagotto, F; Fornerod, M,期刊：Journal of cell science, 页码：1793-1802 , 文章类型： Article，,卷期：2008年121-11] The standard model of Wnt signaling specifies that after receipt of a Wnt ligand at the membranous receptor complex, downstream mediators inhibit a cytoplasmic destruction complex, allowing beta-catenin to accumulate in ... UV-induced degradation of securin is mediated by SKP1-CUL1-beta TrCP E3 ubiquitin ligase [作者：Limon-Mortes, MC; Mora-Santos, M; Espina, A; Pintor-Toro, JA; Lopez-Roman, A; Tortolero, M; Romero, F,期刊：Journal of cell science, 页码：1825-1831 , 文章类型： Article，,卷期：2008年121-11] Securin is a chaperone protein with bifunctional properties. It binds to separase to inhibit premature sister chromatid separation until the onset of anaphase, and it also takes part in cell-cycle arrest after UV irradia... Distinct targeting pathways for the membrane insertion of tail-anchored (TA) proteins [作者：Favaloro, V; Spasic, M; Schwappach, B; Dobberstein, B,期刊：Journal of cell science, 页码：1832-1840 , 文章类型： Article，,卷期：2008年121-11] Tail-anchored (TA) proteins are characterised by a C-terminal transmembrane region that mediates post-translational insertion into the membrane of the endoplasmic reticulum (ER). We have investigated the requirements for... Interactions with titin and myomesin target obscurin and obscurin-like 1 to the M-band - implications for hereditary myopathies [作者：Fukuzawa, A; Lange, S; Holt, M; Vihola, A; Carmignac, V; Ferreiro, A; Udd, B; Gautel, M,期刊：Journal of cell science, 页码：1841-1851 , 文章类型： Article，,卷期：2008年121-11] Obscurin, a giant modular muscle protein implicated in G-protein and protein-kinase signalling, can localize to both sarcomeric Z-disks and M-bands. Interaction of obscurin with the Z-disk is mediated by Z-disk titin. He... Identification of a novel N-terminal hydrophobic sequence that targets proteins to lipid droplets [作者：Zehmer, JK; Bartz, R; Liu, PS; Anderson, RGW,期刊：Journal of cell science, 页码：1852-1860 , 文章类型： Article，,卷期：2008年121-11] AAM-B is a putative methyltransferase that is a resident protein of lipid droplets. We have identified an N-terminal 28 amino acid hydrophobic sequence that is necessary and sufficient for targeting the protein to drople... Mitochondrial nucleoids undergo remodeling in response to metabolic cues [作者：Kucej, M; Kucejova, B; Subramanian, R; Chen, XJ; Butow, RA,期刊：Journal of cell science, 页码：1861-1868 , 文章类型： Article，,卷期：2008年121-11] Mitochondrial DNA is organized as a nucleoprotein complex called the nucleoid. Its major protein components have been identified in different organisms, but it is yet unknown whether nucleoids undergo any form of remodel... Reduction of Crk and CrkL expression blocks reelin-induced dendritogenesis [作者：Matsuki, T; Pramatarova, A; Howell, BW,期刊：Journal of cell science, 页码：1869-1875 , 文章类型： Article，,卷期：2008年121-11] The reelin signaling pathway regulates nervous system function after birth, in addition to its role in regulating neuronal positioning during embryogenesis. The receptor-dependent, reelin-induced tyrosine phosphorylation... Replication-timing-correlated spatial chromatin arrangements in cancer and in primate interphase nuclei [作者：Grasser, F; Neusser, M; Fiegler, H; Thormeyer, T; Cremer, M; Carter, NP; Cremer, T; Muller, S,期刊：Journal of cell science, 页码：1876-1886 , 文章类型： Article，,卷期：2008年121-11] Using published high-resolution data on S-phase replication timing, we determined the three-dimensional (3D) nuclear arrangement of 33 very-early-replicating and 31 very-late-replicating loci. We analyzed diploid human, ... Nesprin-2 Giant (NUANCE) maintains nuclear envelope architecture and composition in skin [作者：Luke, Y; Zaim, H; Karakesisoglou, I; Jaeger, VM; Sellin, L; Lu, WS; Schneider, M; Neumann, S; Beijer, A; Munck, M; Padmakumar, VC; Gloy, JC; Walz, G; Noegel, AA,期刊：Journal of cell science, 页码：1887-1898 , 文章类型： Article，,卷期：2008年121-11] Giant isoforms, encoded by Nesprin-1 (Syne1) and Nesprin-2 (Syne2), are multifunctional actin-binding and nuclear-envelope-associated proteins belonging to the spectrin superfamily. Here, we investigate the function of N... The R246S hot-spot p53 mutant exerts dominant-negative effects in embryonic stem cells in vitro and in vivo [作者：Lee, MK; Sabapathy, K,期刊：Journal of cell science, 页码：1899-1906 , 文章类型： Article，,卷期：2008年121-11] p53 is the most frequently mutated tumour-suppressor gene in human cancers. Mutant p53 is thought to contribute to carcinogenesis by the acquisition of gain-of-function properties or through the exertion of dominant-nega... The intraflagellar transport protein IFT57 is required for cilia maintenance and regulates IFT-particle-kinesin-II dissociation in vertebrate photoreceptors [作者：Krock, BL; Perkins, BD,期刊：Journal of cell science, 页码：1907-1915 , 文章类型： Article，,卷期：2008年121-11] Defects in protein transport within vertebrate photoreceptors can result in photoreceptor degeneration. In developing and mature photoreceptors, proteins targeted to the outer segment are transported through the connecti... Novel self-association of the APC molecule affects APC clusters and cell migration [作者：Li, ZY; Kroboth, K; Newton, IP; Nathke, IS,期刊：Journal of cell science, 页码：1916-1925 , 文章类型： Article，,卷期：2008年121-11] Truncation mutations in the adenomatous polyposis coli (APC) gene are responsible for familial and sporadic colorectal cancer. APC is a multifunctional protein involved in cell migration, proliferation and differentiatio... yuri gagarin is required for actin, tubulin and basal body functions in Drosophila spermatogenesis [作者：Texada, MJ; Simonette, RA; Johnson, CB; Deery, WJ; Beckingham, KM,期刊：Journal of cell science, 页码：1926-1936 , 文章类型： Article，,卷期：2008年121-11] Males of the genus Drosophila produce sperm of remarkable length. Investigation of giant sperm production in Drosophila melanogaster has demonstrated that specialized actin and microtubule structures play key roles. The ... A new model for hemoglobin ingestion and transport by the human malaria parasite Plasmodium falciparum [作者：Lazarus, MD; Schneider, TG; Taraschi, TF,期刊：Journal of cell science, 页码：1937-1949 , 文章类型： Article，,卷期：2008年121-11] The current model for hemoglobin ingestion and transport by intraerythrocytic Plasmodium falciparum malaria parasites shares similarities with endocytosis. However, the model is largely hypothetical, and the mechanisms r... The importance of stupidity in scientific research [作者：Schwartz, MA,期刊：Journal of cell science, 页码：1771-1771 , 文章类型： Editorial Material，,卷期：2008年121-11]