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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共21条记录   CED-9 and mitochondrial homeostasis in C-elegans muscle [作者：Tan, FJ; Husain, M; Manlandro, CM; Koppenol, M; Fire, AZ; Hill, RB,期刊：Journal of cell science, 页码：3373-3382 , 文章类型： Article，,卷期：2008年121-20] Mitochondrial homeostasis reflects a dynamic balance between membrane fission and fusion events thought essential for mitochondrial function. We report here that altered expression of the C. elegans BCL2 homolog CED-9 af... The protein phosphatase PP2A-B ' subunit Widerborst is a negative regulator of cytoplasmic activated Akt and lipid metabolism in Drosophila [作者：Vereshchagina, N; Ramel, MC; Bitoun, E; Wilson, C,期刊：Journal of cell science, 页码：3383-3392 , 文章类型： Article，,卷期：2008年121-20] Inappropriate regulation of the PI3-kinase/PTEN/Akt kinase-signalling cassette, a key downstream target of insulin/insulinlike growth factor signalling (IIS), is associated with several major human diseases such as diabe... Reduced tumorigenesis in mouse mammary cancer cells following inhibition of Pea3-or Erm-dependent transcription [作者：Firlej, V; Ladam, F; Brysbaert, G; Dumont, P; Fuks, F; de Launoit, Y; Benecke, A; Chotteau-Lelievre, A,期刊：Journal of cell science, 页码：3393-3402 , 文章类型： Article，,卷期：2008年121-20] Pea3 and Erm are transcription factors expressed in normal developing branching organs such as the mammary gland. Deregulation of their expression is generally associated with tumorigenesis and particularly breast cancer... G-actin regulates rapid induction of actin nucleation by mDia1 to restore cellular actin polymers [作者：Higashida, C; Suetsugu, S; Tsuji, T; Monypenny, J; Narumiya, S; Watanabe, N,期刊：Journal of cell science, 页码：3403-3412 , 文章类型： Article，,卷期：2008年121-20] mDia1 belongs to the formin family of proteins that share FH1 and FH2 domains. Although formins play a critical role in the formation of many actin-based cellular structures, the physiological regulation of formin-mediat... Murine CENPF interacts with syntaxin 4 in the regulation of vesicular transport [作者：Pooley, RD; Moynihan, KL; Soukoulis, V; Reddy, S; Francis, R; Lo, C; Ma, LJ; Bader, DM,期刊：Journal of cell science, 页码：3413-3421 , 文章类型： Article，,卷期：2008年121-20] Syntaxin 4 is a component of the SNARE complex that regulates membrane docking and fusion. Using a yeast two-hybrid screen, we identify a novel interaction between syntaxin 4 and cytoplasmic murine CENPF, a protein previ... Human kidney anion exchanger 1 localisation in MDCK cells is controlled by the phosphorylation status of two critical tyrosines [作者：Williamson, RC; Brown, ACN; Mawby, WJ; Toye, AM,期刊：Journal of cell science, 页码：3422-3432 , 文章类型： Article，,卷期：2008年121-20] An important question in renal physiology is how the alpha-intercalated cells of the kidney regulate the distribution of the basolateral kidney anion exchanger 1 (kAE1) according to systemic acid-base status. Previous wo... The ENTH and C-terminal domains of Dictyostelium epsin cooperate to regulate the dynamic interaction with clathrin-coated pits [作者：Brady, RJ; Wen, YJ; O'Halloran, TJ,期刊：Journal of cell science, 页码：3433-3444 , 文章类型： Article，,卷期：2008年121-20] Epsin contains a phospholipid-binding ENTH domain coupled to C-terminal domain motifs that bind coated pit proteins. We examined how these domains interact to influence epsin function and localization in Dictyostelium. A... Sorting of EGF and transferrin at the plasma membrane and by cargo-specific signaling to EEA1-enriched endosomes [作者：Leonard, D; Hayakawa, A; Lawe, D; Lambright, D; Bellve, KD; Standley, C; Lifshitz, LM; Fogarty, KE; Corvera, S,期刊：Journal of cell science, 页码：3445-3458 , 文章类型： Article，,卷期：2008年121-20] The biological function of receptors is determined by their appropriate trafficking through the endosomal pathway. Following internalization, the transferrin (Tf) receptor quantitatively recycles to the plasma membrane, ... Loss of protein kinase C epsilon results in impaired cutaneous wound closure and myofibroblast function [作者：Leask, A; Shi-Wen, X; Khan, K; Chen, YL; Holmes, A; Eastwood, M; Denton, CP; Black, CM; Abraham, DJ,期刊：Journal of cell science, 页码：3459-3467 , 文章类型： Article，,卷期：2008年121-20] Cutaneous wound repair requires the de novo induction of a specialized form of fibroblast, the alpha-smooth muscle actin (alpha-SMA)-expressing myofibroblast, which migrates into the wound where it adheres to and contrac... Mitochondrial dysfunction and HIF1 alpha stabilization in inflammation [作者：Garedew, A; Moncada, S,期刊：Journal of cell science, 页码：3468-3475 , 文章类型： Article，,卷期：2008年121-20] Activation of murine-derived J774.A1 macrophages with interferon. and lipopolysaccharide leads to a progressive mitochondrial defect characterized by inhibition of oxygen consumption and a decrease in the generation of A... TorsinA binds the KASH domain of nesprins and participates in linkage between nuclear envelope and cytoskeleton [作者：Nery, FC; Zeng, J; Niland, BP; Hewett, J; Farley, J; Irimia, D; Li, YQ; Wiche, G; Sonnenberg, A; Breakefield, XO,期刊：Journal of cell science, 页码：3476-3486 , 文章类型： Article，,卷期：2008年121-20] A specific mutation(Delta E) in torsinA underlies most cases of the dominantly inherited movement disorder, early-onset torsion dystonia (DYT1). TorsinA, a member of the AAA+ ATPase superfamily, is located within the lum... Expression of pro- and anti-angiogenic isoforms of VEGF is differentially regulated by splicing and growth factors [作者：Nowak, DG; Woolard, J; Amin, EM; Konopatskaya, O; Saleem, MA; Churchill, AJ; Ladomery, MR; Harper, SJ; Bates, DO,期刊：Journal of cell science, 页码：3487-3495 , 文章类型： Article，,卷期：2008年121-20] Vascular endothelial growth factor A (VEGFA; hereafter referred to as VEGF) is a key regulator of physiological and pathological angiogenesis. Two families of VEGF isoforms are generated by alternate splice-site selectio... Mechanotransduction - a field pulling together? [作者：Chen, CS,期刊：Journal of cell science, 页码：3285-3292 , 文章类型： Review，,卷期：2008年121-20] Mechanical stresses are ever present in the cellular environment, whether through external forces that are applied to tissues or endogenous forces that are generated within the active cytoskeleton. Despite the wide array... The regulation of salt transport and blood pressure by the WNK-SPAK/OSR1 signalling pathway [作者：Richardson, C; Alessi, DR,期刊：Journal of cell science, 页码：3293-3304 , 文章类型： Article，,卷期：2008年121-20] It has recently been shown that the WNK [with-no-K(Lys)] kinases (WNK1, WNK2, WNK3 and WNK4) have vital roles in the control of salt homeostasis and blood pressure. This Commentary focuses on recent findings that have un... Myofibroblast communication is controlled by intercellular mechanical coupling [作者：Follonier, L; Schaub, S; Meister, JJ; Hinz, B,期刊：Journal of cell science, 页码：3305-3316 , 文章类型： Article，,卷期：2008年121-20] Neoformation of intercellular adherens junctions accompanies the differentiation of fibroblasts into contractile myofibroblasts, a key event during development of fibrosis and in wound healing. We have previously shown t... Snail is required for TGF beta-induced endothelial-mesenchymal transition of embryonic stem cell-derived endothelial cells [作者：Kokudo, T; Suzuki, Y; Yoshimatsu, Y; Yamazaki, T; Watabe, T; Miyazono, K,期刊：Journal of cell science, 页码：3317-3324 , 文章类型： Article，,卷期：2008年121-20] Epithelial-mesenchymal transition (EMT) plays important roles in various physiological and pathological processes, and is regulated by signaling pathways mediated by cytokines, including transforming growth factor beta (...