- Structural Analysis of a Highly Glycosylated and Unliganded gp120-Based Antigen Using Mass Spectrometry
[作者:Wang, LW; Qin, YL; Ilchenko, S; Bohon, J; Shi, WX; Cho, MW; Takamoto, K; Chance, MR,期刊:Biochemistry, 页码:9032-9045 , 文章类型: Article,,卷期:2010年49-42]
- Structural characterization of the HIV-1 envelope protein gp120 is very important for providing an understanding of the protein's immunogenicity and its binding to cell receptors. So far, the crystallographic structure o...
- Inscribing the Perimeter of the PagP Hydrocarbon Ruler by Site-Specific Chemical Alkylation
[作者:Khan, MA; Moktar, J; Mott, PJ; Vu, M; McKie, AH; Pinter, T; Hof, F; Bishop, RE,期刊:Biochemistry, 页码:9046-9057 , 文章类型: Article,,卷期:2010年49-42]
- The Escherichia coil outer membrane phospholipid:lipid A palmitoyltransferase PagP selects palmitate chains using its beta-barrel-interior hydrocarbon ruler and interrogates phospholipid donors by gating them laterally t...
- Thermodynamic Characterization of RNA Triloops
[作者:Thulasi, P; Pandya, LK; Znosko, BM,期刊:Biochemistry, 页码:9058-9062 , 文章类型: Article,,卷期:2010年49-42]
- Relatively few thermodynamic parameters are available for RNA triloops. Therefore, 24 stem-loop sequences containing naturally occurring triloops were optically melted, and the thermodynamic parameters Delta H degrees, D...
- Compound Ice-Binding Site of an Antifreeze Protein Revealed by Mutagenesis and Fluorescent Tagging
[作者:Garnham, CP; Natarajan, A; Middleton, AJ; Kuiper, MJ; Braslavsky, I; Davies, PL,期刊:Biochemistry, 页码:9063-9071 , 文章类型: Article,,卷期:2010年49-42]
- By binding to the surface of ice crystals, type III antifreeze protein (A FP) can depress the freezing point of fish blood to below that of freezing seawater. This 7-kDa globular protein is encoded by a multigene family ...
- Understanding the Molecular Activity of Alkaline Sphingomyelinase (NPP7) by Computer Modeling
[作者:Duan, JX; Wu, J; Cheng, YJ; Duan, RD,期刊:Biochemistry, 页码:9096-9105 , 文章类型: Article,,卷期:2010年49-42]
- The enzymes in the nucleotide pyrophosphatase/phosphodiesterase (NPP) family have various substrates such as nucleotides, phospholipids, and sphingolipids. The substrate specificity in relation to their structures is lar...
- Combinatorial Selection of DNA Thioaptamers Targeted to the HA Binding Domain of Human CD44
[作者:Somasunderam, A; Thiviyanathan, V; Tanaka, T; Li, X; Neerathilingam, M; Lokesh, GLR; Mann, A; Peng, Y; Ferrari, M; Klostergaard, J; Gorenstein, DG,期刊:Biochemistry, 页码:9106-9112 , 文章类型: Article,,卷期:2010年49-42]
- CD44, the primary receptor for hyaluronic acid, plays an important role in tumor growth and metastasis. CD44 hyaluronic acid interactions can be exploited for targeted delivery of anticancer agents specifically to cancer...
- Design of High-Activity Mutants of Human Butyrylcholinesterase against (-)-Cocaine: Structural and Energetic Factors Affecting the Catalytic Efficiency
[作者:Zheng, F; Yang, WC; Xue, L; Hou, SR; Liu, JJ; Zhan, CG,期刊:Biochemistry, 页码:9113-9119 , 文章类型: Article,,卷期:2010年49-42]
- The present study was aimed to explore the correlation between the protein structure and catalytic efficiency of butyrylcholinesterase (BChE) mutants against (-)-cocaine by modeling the rate-determining transition state ...
|