- Increase of the pharmacological and pharmacokinetic efficacy of negatively charged polypeptide recombinant hirudin in rats via parenteral route by association with cationic liposomes
[作者:Meng, M; Liu, Y; Wang, YB; Wang, JC; Zhang, H; Wang, XQ; Zhang, X; Lu, WL; Zhang, Q,期刊:Journal of controlled release, 页码:113-119 , 文章类型: Article,,卷期:2008年128-2]
- Two biodegradable cationic lipids, stearylamine and DC-Chol, were chosen to investigate the effect of cationic lipids on the in vitro and in vivo characteristics of hydrophilic proteins or peptides of low isoelectric poi...
- Preparation and brain delivery property of biodegradable polymersomes conjugated with OX26
[作者:Pang, ZQ; Lu, W; Gao, HL; Hu, KL; Chen, J; Zhang, CL; Gao, XL; Jiang, XG; Zhu, CQ,期刊:Journal of controlled release, 页码:120-127 , 文章类型: Article,,卷期:2008年128-2]
- A novel drug carrier for brain delivery, poly(ethyleneglycol)-poly(epsilon-caprolactone) (PEG-PCL) polymersomes conjugated with mouse-anti-rat monoclonal antibody OX26 (OX26-PO), was developed and its brain delivery prop...
- Controlled release carrier of BSA made by W/O/W emulsion method containing PLGA and hydroxyapatite
[作者:Ho, ML; Fu, YC; Wang, GJ; Chen, HT; Chang, JK; Tsai, TH; Wang, CK,期刊:Journal of controlled release, 页码:142-148 , 文章类型: Article,,卷期:2008年128-2]
- This study relates to the Bovine Serum Albumin (BSA) protein-controlled release system with Poly(lactic-glycolic acid) (PLGA) biodegradable polymer. It also has special double emulsification carriers containing alkaline ...
- Synthesis of (Dex-HMDI)-g-PEIs as effective and low cytotoxic nonviral gene vectors
[作者:Sun, YX; Xiao, W; Cheng, SX; Zhang, XZ; Zhuo, RX,期刊:Journal of controlled release, 页码:171-178 , 文章类型: Article,,卷期:2008年128-2]
- Gene vectors, (dextran-hexamethylenediisocyanate)-g-polyethylenimines ((Dex-HMDI)-g-PEIs), were synthesized through grafting low molecular weight (800 Da) branched polyethylenimine (PEI) to HMDI functionalized dextrans w...
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