- Oxytocin deficiency impairs maternal skeletal remodeling
[作者:Liu, X; Shimono, K; Zhu, LL; Li, JH; Peng, YZ; Imam, A; Iqbal, J; Moonga, S; Colaianni, G; Su, C; Lu, ZH; Iwamoto, M; Pacifici, M; Zallone, A; Sun, L; Zaidi, M,期刊:Biochemical and Biophysical Research Communications, 页码:161-166 , 文章类型: Article,,卷期:2009年388-1]
- We have reported that the posterior pituitary hormone, oxytocin (OT), known for its effects in inducing parturition, lactation and social bonding, is also a skeletal hormone. Here, we demonstrate that OT plays a key role...
- Lycopene inhibits PDGF-BB-induced retinal pigment epithelial cell migration by suppression of PI3K/Akt and MAPK pathways
[作者:Chan, CM; Fang, JY; Lin, HH; Yang, CY; Hung, CF,期刊:Biochemical and Biophysical Research Communications, 页码:172-176 , 文章类型: Article,,卷期:2009年388-1]
- Retinal pigment epithelial (RPE) cells play a dominant role in the development of proliferative vitreoretinopathy (PVR), which is the leading cause of failure in retinal reattachment surgery. Several studies have shown t...
- Identification of the vesicular nucleotide transporter (VNUT) in taste cells
[作者:Iwatsuki, K; Ichikawa, R; Hiasa, M; Moriyama, Y; Torii, K; Uneyama, H,期刊:Biochemical and Biophysical Research Communications, 页码:1-5 , 文章类型: Article,,卷期:2009年388-1]
- Taste cells are chemosensory epithelial cells that sense distinct taste qualities. It is the type II taste cell that express G-protein coupled receptors to sense either umami, sweet, or bitter compounds. Whereas several ...
- Phosphorylation of dGMP analogs by vaccinia virus TMP kinase and human GMP kinase
[作者:Auvynet, C; Topalis, D; Caillat, C; Munier-Lehmann, H; Seclaman, E; Balzarini, J; Agrofoglio, LA; Kaminski, PA; Meyer, P; Deville-Bonne, D; El Amri, C,期刊:Biochemical and Biophysical Research Communications, 页码:6-11 , 文章类型: Article,,卷期:2009年388-1]
- Vaccinia virus thymidylate kinase, although similar in sequence to human TMP kinase, has broader substrate specificity and phosphorylates (E)-5-(2-bromovinyl)-dUMP and dGMP. Modified guanines such as glyoxal-dG, 8-oxo-dG...
- Anchored and soluble gangliosides contribute to myelosupportivity of stromal cells
[作者:Ziulkoski, AL; dos Santos, AXS; Andrade, CMB; Trindade, VMT; Daniotti, JL; Borojevic, R; Guma, FCR,期刊:Biochemical and Biophysical Research Communications, 页码:17-20 , 文章类型: Article,,卷期:2009年388-1]
- Stroma-mediated myelopoiesis depends upon growth factors and an appropriate intercellular microenvironment. Previous studies have demonstrated that gangliosides, produced by hepatic stromal cell types, are required for o...
- Dual roles of a conserved pair, Arg23 and Ser20, in recognition of multiple substrates in alpha-aminoadipate aminotransferase from Thermus thermophilus
[作者:Ouchi, T; Tomita, T; Miyagawa, T; Kuzuyama, T; Nishiyama, M,期刊:Biochemical and Biophysical Research Communications, 页码:21-27 , 文章类型: Article,,卷期:2009年388-1]
- To clarify the mechanism for substrate recognition of alpha-aminoadipate aminotransferase (AAA-AT) from Thermus thermophilus, the crystal structure of AAA-AT complexed with N-(5'-phosphopyridoxyl)-L-glutamate (PPE) was d...
- Relationship between anti-fibrotic effect of Panax notoginseng saponins and serum cytokines in rat hepatic fibrosis
[作者:Peng, XD; Dai, LL; Huang, CQ; He, CM; Yang, B; Chen, LJ,期刊:Biochemical and Biophysical Research Communications, 页码:31-34 , 文章类型: Article,,卷期:2009年388-1]
- The aim of this study was to investigate the relationship between anti-fibrotic effect of Panax notoginseng saponins (PNS) and serum cytokines in rat hepatic fibrosis. Hepatic fibrosis induced by carbon tetrachloride (CC...
- Functional elucidation of MiR-34 in osteosarcoma cells and primary tumor samples
[作者:He, CL; Xiong, JY; Xu, XP; Lu, W; Liu, LJ; Xiao, DM; Wang, DP,期刊:Biochemical and Biophysical Research Communications, 页码:35-40 , 文章类型: Article,,卷期:2009年388-1]
- MiR-34s have been characterized as direct p53 targets, which induce apoptosis, cell cycle arrest, and senescence. MiR-34s were found to associate with tumorigenesis. Thus far, there is no study on the role of MiR-34s in ...
- Enhanced SUMOylation of proteins containing a SUMO-interacting motif by SUMO-Ubc9 fusion
[作者:Kim, ET; Kim, KK; Matunis, MJ; Ahn, JH,期刊:Biochemical and Biophysical Research Communications, 页码:41-45 , 文章类型: Article,,卷期:2009年388-1]
- Identifying new targets for SUMO and understanding the function of protein SUMOylation are largely limited by low level of SUMOylation. It was found recently that Ubc9, the SUMO E2 conjugating enzyme, is covalently modif...
- Long-term high glucose concentration influences Akt, ERK1/2, and PTP1B protein expression in human aortic smooth muscle cells
[作者:Popov, D; Nemecz, M; Dumitrescu, M; Georgescu, A; Bohmer, FD,期刊:Biochemical and Biophysical Research Communications, 页码:51-55 , 文章类型: Article,,卷期:2009年388-1]
- Hyperglycemia stimulates a plethora of intracellular signaling pathways within the cells of the vascular wall resulting in dysfunction-associated pathologies. Most of the studies reported so far explored the effect of ra...
- Targeted manipulation of mammalian genomes using designed zinc finger nucleases
[作者:Kandavelou, K; Ramalingam, S; London, V; Mani, M; Wu, J; Alexeev, V; Civin, CI; Chandrasegaran, S,期刊:Biochemical and Biophysical Research Communications, 页码:56-61 , 文章类型: Article,,卷期:2009年388-1]
- Targeted introduction of a double-stranded break (DSB) using designer zinc finger nucleases (ZFNs) in mammalian cells greatly enhances gene targeting - homologous recombination (HR) at a chosen endogenous target gene, wh...
- DNA-binding specificity of the Lon protease alpha-domain from Brevibacillus thermoruber WR-249
[作者:Lin, YC; Lee, HC; Wang, I; Hsu, CH; Liao, JH; Lee, AYL; Chen, CP; Wu, SH,期刊:Biochemical and Biophysical Research Communications, 页码:62-66 , 文章类型: Article,,卷期:2009年388-1]
- Lon protease has been well studied in many aspects; however, the DNA-binding specificity of Lon in prokaryotes has not been clearly identified. Here we examined the DNA-binding activity of Lon protease alpha-domains from...
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