- Emerging roles of SUMO modification in arthritis
[作者:Yan, DY; Davis, FJ; Sharrocks, AD; Im, HJ,期刊:Gene, 页码:1-15 , 文章类型: Review,,卷期:2010年466-40180]
- Dynamic modification involving small ubiquitin-like modifier (SUMO) has emerged as a new mechanism of protein regulation in mammalian biology. Sumoylation is an ATP-dependent, reversible post-translational modification w...
- Cell cycle-regulated expression and subcellular localization of a kinesin-8 member human KIF18B
[作者:Lee, YM; Kim, E; Park, M; Moon, E; Ahn, SM; Kim, W; Hwang, KB; Kim, YK; Choi, W; Kim, W,期刊:Gene, 页码:16-25 , 文章类型: Article,,卷期:2010年466-40180]
- The human genome contains genes encoding for over 40 different types of kinesin and kinesin-like proteins. Of these, the functions of 13 kinesins remain uncharacterized. In this study, we constructed a plasmid containing...
- Cloning, characterization, and subcellular localization of a Trypanosoma cruzi argonaute protein defining a new subfamily distinctive of trypanosomatids
[作者:Silva, MRG; Tosar, JP; Frugier, M; Pantano, S; Bonilla, B; Esteban, L; Serra, E; Rovira, C; Robello, C; Cayota, A,期刊:Gene, 页码:26-35 , 文章类型: Article,,卷期:2010年466-40180]
- Over the last years an expanding family of small non-coding RNAs (sRNA) has been identified in eukaryotic genomes which behave as sequence-specific triggers for mRNA degradation, translation repression, heterochromatin f...
- Controlled removal of a nonviral episomal vector from transfected cells
[作者:Rupprecht, S; Hagedorn, C; Seruggia, D; Magnusson, T; Wagner, E; Ogris, M; Lipps, HJ,期刊:Gene, 页码:36-42 , 文章类型: Article,,卷期:2010年466-40180]
- An ideal vector to be used in gene therapy should allow long-term and regulated expression of the therapeutic sequence, but in many cases, it would be most desirable to remove all ectopic vector sequences from the cell o...
- Characterization of the promoter region of TCblR/CD320 gene, the receptor for cellular uptake of transcobalamin-bound cobalamin
[作者:Jiang, WX; Sequeira, JM; Nakayama, Y; Lai, SC; Quadros, EV,期刊:Gene, 页码:49-55 , 文章类型: Article,,卷期:2010年466-40180]
- Cellular uptake of cobalamin (Cbl) is mediated by the transcobalamin receptor (TCblR) that binds and internalizes transcobalamin (TC) saturated with Cbl. These receptors are expressed in actively proliferating cells and ...
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