- High-Dose Daunorubicin in Older Patients with Acute Myeloid Leukemia
[作者:Lowenberg, B; Ossenkoppele, GJ; van Putten, W; Schouten, HC; Graux, C; Ferrant, A; Sonneveld, P; Maertens, J; Jongen-Lavrencic, M; von Lilienfeld-Toal, M; Biemond, BJ; Vellenga, E; Kooy, MV; Verdonck, LF; Beck, J; Dohner, H; Gratwohl, A; Pabst, T; Verhoef, G,期刊:New England Journal of Medicine, 页码:1235-1248 , 文章类型: Article,,卷期:2009年361-13]
- BackgroundA complete remission is essential for prolonging survival in patients with acute myeloid leukemia (AML). Daunorubicin is a cornerstone of the induction regimen, but the optimal dose is unknown. In older patient...
- Anthracycline Dose Intensification in Acute Myeloid Leukemia
[作者:Fernandez, HF; Sun, ZX; Yao, XP; Litzow, MR; Luger, SM; Paietta, EM; Racevskis, J; Dewald, GW; Ketterling, RP; Bennett, JM; Rowe, JM; Lazarus, HM; Tallman, MS,期刊:New England Journal of Medicine, 页码:1249-1259 , 文章类型: Article,,卷期:2009年361-13]
- BackgroundIn young adults with acute myeloid leukemia (AML), intensification of the anthracycline dose during induction therapy has improved the rate of complete remission but not of overall survival. We evaluated the us...
- Comparative Efficacy of Inactivated and Live Attenuated Influenza Vaccines
[作者:Monto, AS; Ohmit, SE; Petrie, JG; Johnson, E; Truscon, R; Teich, E; Rotthoff, J; Boulton, M; Victor, JC,期刊:New England Journal of Medicine, 页码:1260-1267 , 文章类型: Article,,卷期:2009年361-13]
- BackgroundThe efficacy of influenza vaccines may vary from year to year, depending on a variety of factors, and may differ for inactivated and live attenuated vaccines.MethodsWe carried out a randomized, double-blind, pl...
- A Double-Blind, Delayed-Start Trial of Rasagiline in Parkinson's Disease
[作者:Olanow, CW; Rascol, O; Hauser, R; Feigin, PD; Jankovic, J; Lang, A; Langston, W; Melamed, E; Poewe, W; Stocchi, F; Tolosa, E,期刊:New England Journal of Medicine, 页码:1268-1278 , 文章类型: Article,,卷期:2009年361-13]
- BackgroundA therapy that slows disease progression is the major unmet need in Parkinson's disease.MethodsIn this double-blind trial, we examined the possibility that rasagiline has disease-modifying effects in Parkinson'...
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