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  • High-Dose Daunorubicin in Older Patients with Acute Myeloid Leukemia
    [作者:Lowenberg, B; Ossenkoppele, GJ; van Putten, W; Schouten, HC; Graux, C; Ferrant, A; Sonneveld, P; Maertens, J; Jongen-Lavrencic, M; von Lilienfeld-Toal, M; Biemond, BJ; Vellenga, E; Kooy, MV; Verdonck, LF; Beck, J; Dohner, H; Gratwohl, A; Pabst, T; Verhoef, G,期刊:New England Journal of Medicine, 页码:1235-1248 , 文章类型: Article,,卷期:2009年361-13]
  • BackgroundA complete remission is essential for prolonging survival in patients with acute myeloid leukemia (AML). Daunorubicin is a cornerstone of the induction regimen, but the optimal dose is unknown. In older patient...
  • Anthracycline Dose Intensification in Acute Myeloid Leukemia
    [作者:Fernandez, HF; Sun, ZX; Yao, XP; Litzow, MR; Luger, SM; Paietta, EM; Racevskis, J; Dewald, GW; Ketterling, RP; Bennett, JM; Rowe, JM; Lazarus, HM; Tallman, MS,期刊:New England Journal of Medicine, 页码:1249-1259 , 文章类型: Article,,卷期:2009年361-13]
  • BackgroundIn young adults with acute myeloid leukemia (AML), intensification of the anthracycline dose during induction therapy has improved the rate of complete remission but not of overall survival. We evaluated the us...