- Intensity of Continuous Renal-Replacement Therapy in Critically Ill Patients
[作者:Bellomo, R; Cass, A; Norton, R; Gallagher, M; Lo, S; Su, S; Cole, L; Finfer, S; McArthur, C; McGuinness, S; Myburgh, J; Scheinkestel, C; Bellomo, R; Lee, J; Ali, D; Cass, A; Cole, L; Finfer, S; Gallagher, M; Goldsmith, D; McGuinness, S; Myburgh, J; Norton, R; Scheinkestel, C; Banerjee, A; Bhonagiri, D; Blythe, D; Botha, J; Cade, J; Cole, L; Dobb, G; Eddington, J; Finfer, S; Flabouris, A; French, C; Garrett, P; Henderson, S; Ihle, B; Joyce, C; Kalkoff, M; Lipman, J; McArthur, C; McGuinness, S; Milliss, D; Mitchell, I; Morgan, J; Myburgh, J; Nair, P; Orford, N; Raza, A; Scheinkestel, C; Shehabi, Y; Tobin, A; Totaro, R; Turner, A; Wright, C; Ali, D; Lee, J; Little, L; Morrison, A; Regaglia, G; Shukla, R; Baigent, C; Emberson, J; Wheeler, D; Young, D; Billot, L; Bompoint, S; Heritier, S; Lo, SN; Pillai, A; Su, S; Pandey, S; Ryan, S; Schmidt, M; Starzec, G; Vijayan, B; Mitchell, I; Ashley, R; Gissane, J; Malchukova, K; Ranse, J; Raza, A; Nand, K; Sara, T; Cheung, W; Fugaccia, E; Lawrence, P,期刊:New England Journal of Medicine, 页码:1627-1638 , 文章类型: Article,,卷期:2009年361-17]
- BackgroundThe optimal intensity of continuous renal-replacement therapy remains unclear. We conducted a multicenter, randomized trial to compare the effect of this therapy, delivered at two different levels of intensity,...
- Strict Blood-Pressure Control and Progression of Renal Failure in Children
[作者:Wuhl, E; Trivelli, A; Picca, S; Litwin, M; Peco-Antic, A; Zurowska, A; Testa, S; Jankauskiene, A; Emre, S; Caldas-Afonso, A; Anarat, A; Niaudet, P; Mir, S; Bakkaloglu, A; Enke, B; Montini, G; Wingen, AM; Sallay, P; Jeck, N; Berg, U; Caliskan, S; Wygoda, S; Hohbach-Hohenfellner, K; Dusek, J; Urasinski, T; Arbeiter, K; Neuhaus, T; Gellermann, J; Drozdz, D; Fischbach, M; Moller, K; Wigger, M; Peruzzi, L; Mehls, O; Schaefer, F,期刊:New England Journal of Medicine, 页码:1639-1650 , 文章类型: Article,,卷期:2009年361-17]
- BackgroundAlthough inhibition of the renin-angiotensin system delays the progression of renal failure in adults with chronic kidney disease, the blood-pressure target for optimal renal protection is controversial. We ass...
- Multicenter Analysis of Glucocerebrosidase Mutations in Parkinson's Disease
[作者:Sidransky, E; Nalls, MA; Aasly, JO; Aharon-Peretz, J; Annesi, G; Barbosa, ER; Bar-Shira, A; Berg, D; Bras, J; Brice, A; Chen, CM; Clark, LN; Condroyer, C; De Marco, EV; Durr, A; Eblan, MJ; Fahn, S; Farrer, MJ; Fung, HC; Gan-Or, Z; Gasser, T; Gershoni-Baruch, R; Giladi, N; Griffith, A; Gurevich, T; Januario, C; Kropp, P; Lang, AE; Lee-Chen, GJ; Lesage, S; Marder, K; Mata, IF; Mirelman, A; Mitsui, J; Mizuta, I; Nicoletti, G; Oliveira, C; Ottman, R; Orr-Urtreger, A; Pereira, LV; Quattrone, A; Rogaeva, E; Rolfs, A; Rosenbaum, H; Rozenberg, R; Samii, A; Samaddar, T; Schulte, C; Sharma, M; Singleton, A; Spitz, M; Tan, EK; Tayebi, N; Toda, T; Troiano, AR; Tsuji, S; Wittstock, M; Wolfsberg, TG; Wu, YR; Zabetian, CP; Zhao, Y; Ziegler, SG,期刊:New England Journal of Medicine, 页码:1651-1661 , 文章类型: Article,,卷期:2009年361-17]
- BackgroundRecent studies indicate an increased frequency of mutations in the gene encoding glucocerebrosidase (GBA), a deficiency of which causes Gaucher's disease, among patients with Parkinson's disease. We aimed to as...
- Cisplatin versus Cisplatin plus Doxorubicin for Standard-Risk Hepatoblastoma
[作者:Perilongo, G; Maibach, R; Shafford, E; Brugieres, L; Brock, P; Morland, B; de Camargo, B; Zsiros, J; Roebuck, D; Zimmermann, A; Aronson, D; Childs, M; Widing, E; Laithier, V; Plaschkes, J; Pritchard, J; Scopinaro, M; MacKinlay, G; Czauderna, P,期刊:New England Journal of Medicine, 页码:1662-1670 , 文章类型: Article,,卷期:2009年361-17]
- BackgroundPreoperative cisplatin alone may be as effective as cisplatin plus doxorubicin in standard-risk hepatoblastoma (a tumor involving three or fewer sectors of the liver that is associated with an alpha-fetoprotein...
- X-Linked Thrombophilia with a Mutant Factor IX (Factor IX Padua)
[作者:Simioni, P; Tormene, D; Tognin, G; Gavasso, S; Bulato, C; Iacobelli, NP; Finn, JD; Spiezia, L; Radu, C; Arruda, VR,期刊:New England Journal of Medicine, 页码:1671-1675 , 文章类型: Article,,卷期:2009年361-17]
- We report a case of juvenile thrombophilia associated with a substitution of leucine for arginine at position 338 (R338L) in the factor IX gene (factor IX-R338L). The level of the mutant factor IX protein in plasma was n...
- A Woman with Fever, Abdominal Pain, and Hypotension after Cesarean SectionCase 33-2009: A 35-Year-Old Woman with Fever, Abdominal Pain, and Hypotension after Cesarean Section
[作者:de Moya, MA; del Carmen, MG; Allain, RM; Hirschberg, RE; Shepard, JAO; Kradin, RL,期刊:New England Journal of Medicine, 页码:1689-1697 , 文章类型: Article,,卷期:2009年361-17]
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- FOXP3 Forkhead Domain Mutation and Regulatory T Cells in the IPEX Syndrome
[作者:d'Hennezel, E; Ben-Shoshan, M; Ochs, HD; Torgerson, TR; Russell, LJ; Lejtenyi, C; Noya, FJ; Jabado, N; Mazer, B; Piccirillo, CA,期刊:New England Journal of Medicine, 页码:1710-1713 , 文章类型: Letter,,卷期:2009年361-17]
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