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  • MMP12, Lung Function, and COPD in High-Risk Populations
    [作者:Hunninghake, GM; Cho, MH; Tesfaigzi, Y; Soto-Quiros, ME; Avila, L; Lasky-Su, J; Stidley, C; Melen, E; Soderhall, C; Hallberg, J; Kull, I; Kere, J; Svartengren, M; Pershagen, G; Wickman, M; Lange, C; Demeo, DL; Hersh, CP; Klanderman, BJ; Raby, BA; Sparrow, D; Shapiro, SD; Silverman, EK; Litonjua, AA; Weiss, ST; Celedon, JC,期刊:New England Journal of Medicine, 页码:2599-2608 , 文章类型: Article,,卷期:2009年361-27]
  • BACKGROUNDGenetic variants influencing lung function in children and adults may ultimately lead to the development of chronic obstructive pulmonary disease ( COPD), particularly in high-risk groups.METHODSWe tested for a...
  • Genomewide Association Study of Leprosy
    [作者:Zhang, FR; Huang, W; Chen, SM; Sun, LD; Liu, H; Li, Y; Cui, Y; Yan, XX; Yang, HT; Yang, RD; Chu, TS; Zhang, C; Zhang, L; Han, JW; Yu, GQ; Quan, C; Yu, YX; Zhang, Z; Shi, BQ; Zhang, LH; Cheng, H; Wang, CY; Lin, Y; Zheng, HF; Fu, XA; Zuo, XB; Wang, Q; Long, H; Sun, YP; Cheng, YL; Tian, HQ; Zhou, FS; Liu, HX; Lu, WS; He, SM; Du, WL; Shen, M; Jin, QY; Wang, Y; Low, HQ; Erwin, T; Yang, NH; Li, JY; Zhao, X; Jiao, YL; Mao, LG; Yin, G; Jiang, ZX; Wang, XD; Yu, JP; Hu, ZH; Gong, CH; Liu, YQ; Liu, RY; Wang, DM; Wei, D; Liu, JX; Cao, WK; Cao, HZ; Li, YP; Yan, WG; Wei, SY; Wang, KJ; Hibberd, ML; Yang, S; Zhang, XJ; Liu, JJ,期刊:New England Journal of Medicine, 页码:2609-2618 , 文章类型: Article,,卷期:2009年361-27]
  • BACKGROUNDThe narrow host range of Mycobacterium leprae and the fact that it is refractory to growth in culture has limited research on and the biologic understanding of leprosy. Host genetic factors are thought to influ...
  • Activated Protein C for Sepsis
    [作者:Toussaint, S; Gerlach, H,期刊:New England Journal of Medicine, 页码:2646-2652 , 文章类型: Article,,卷期:2009年361-27]
  • A 55-year-old man is brought to the emergency department with abdominal pain, fever (temperature, 102.9 degrees F), and dyspnea. His medical history includes an appendectomy 8 years earlier. Abdominal radiography shows f...