- Phase III study, V-15-32, of gefitinib versus docetaxel in previously treated Japanese patients with non-small-cell lung cancer
[作者:Maruyama, R; Nishiwaki, Y; Tamura, T; Yamamoto, N; Tsuboi, M; Nakagawa, K; Shinkai, T; Negoro, S; Imamura, F; Eguchi, K; Takeda, K; Inoue, A; Tomii, K; Harada, M; Masuda, N; Jiang, H; Itoh, Y; Ichinose, Y; Saijo, N; Fukuoka, M,期刊:Journal of clinical oncology, 页码:4244-4252 , 文章类型: Article,,卷期:2008年26-26]
- PurposeThis phase III study (V-15-32) compared gefitinib (250 mg/d) with docetaxel (60 mg/m(2)) in patients (N = 489) with advanced/metastatic non-small-cell lung cancer (NSCLC) who had failed one or two chemotherapy reg...
- Gefitinib versus vinorelbine in chemotherapy-naive elderly patients with advanced non-small-cell lung cancer (INVITE): A randomized, phase II study
[作者:Crino, L; Cappuzzo, F; Zatloukal, P; Reck, M; Pesek, M; Thompson, JC; Ford, HER; Hirsch, FR; Varella-Garcia, M; Ghiorghiu, S; Duffield, EL; Armour, AA; Speake, G; Cullen, M,期刊:Journal of clinical oncology, 页码:4253-4260 , 文章类型: Article,,卷期:2008年26-26]
- PurposeThis phase II, open-label, parallel-group study compared gefitinib with vinorelbine in chemotherapy naive elderly patients with advanced non-small-cell lung cancer (NSCLC).MethodsChemotherapy-naive patients (age >...
- Phase II study of erlotinib in recurrent or metastatic endometrial cancer: NCICIND-148
[作者:Oza, AM; Eisenhauer, EA; Elit, L; Cutz, JC; Sakurada, A; Tsao, MS; Hoskins, PJ; Biagi, J; Ghatage, P; Mazurka, J; Provencher, D; Dore, N; Dancey, J; Fyles, A,期刊:Journal of clinical oncology, 页码:4319-4325 , 文章类型: Article,,卷期:2008年26-26]
- PurposeEpidermal growth factor receptor (EGFR) overexpression is common in endometrial cancers and may have a major role in tumor growth and progression. Erlotinib is an orally active, selective inhibitor of EGFR tyrosin...
- Irinotecan plus carboplatin versus oral etoposide plus carboplatin in extensive small-cell lung cancer: A Randomized phase III trial
[作者:Hermes, A; Bergman, B; Bremnes, R; Ek, L; Fluge, S; Sederholm, C; Sundstrom, S; Thaning, L; Vilsvik, J; Aasebo, U; Sorenson, S,期刊:Journal of clinical oncology, 页码:4261-4267 , 文章类型: Article,,卷期:2008年26-26]
- PurposeA Japanese randomized trial showed superior survival for patients with extensive-disease (ED) small-cell lung cancer (SCLC) receiving irinotecan plus cisplatin compared with etoposide plus cisplatin. The present t...
- Unrelated donor bone marrow transplantation for children with acute myeloid leukemia beyond first remission or refractory to chemotherapy
[作者:Bunin, NJ; Davies, SM; Aplenc, R; Camitta, BM; DeSantes, KB; Goyal, RK; Kapoor, N; Kernan, NA; Rosenthal, J; Smith, FO; Eapen, M,期刊:Journal of clinical oncology, 页码:4326-4332 , 文章类型: Article,,卷期:2008年26-26]
- PurposeIdentify prognostic factors that influence outcome after unrelated donor bone marrow transplantation in children with acute myeloid leukemia (AML).Patients and MethodsIncluded are 268 patients (age <= 18 years) wi...
- Role of KRAS and EGFR as biomarkers of response to erlotinib in National Cancer Institute of Canada Clinical Trials Group study BR.21
[作者:Zhu, CQ; Santos, GD; Ding, K; Sakurada, A; Cutz, JC; Liu, N; Zhang, T; Marrano, P; Whitehead, M; Squire, JA; Kamel-Reid, S; Seymour, L; Shepherd, FA; Tsao, MS,期刊:Journal of clinical oncology, 页码:4268-4275 , 文章类型: Article,,卷期:2008年26-26]
- PurposeTo evaluate the effect of KRAS and epidermal growth factor receptor (EGFR) genotype on the response to erlotinib treatment in the BR.21, placebo-controlled trial.Patients and MethodsWe analyzed 206 tumors for KRAS...
- Diabetes and mortality in men with locally advanced prostate cancer: RTOG 92-02
[作者:Smith, MR; Bae, K; Efstathiou, JA; Hanks, GE; Pilepich, MV; Sandler, HM; Shipley, WU,期刊:Journal of clinical oncology, 页码:4333-4339 , 文章类型: Article,,卷期:2008年26-26]
- PurposeDiabetes is associated with lower risk of prostate cancer. Most men with diabetes are obese, and obesity is associated with greater prostate cancer mortality. Whether diabetes influences outcomes after prostate ca...
- Screening for small-cell lung cancer: A follow-up study of patients with Lambert-Eaton myasthenic syndrome
[作者:Titulaer, MJ; Wirtz, PW; Willems, LNA; van Kralingen, KW; Smitt, PAES; Verschuuren, JJGM,期刊:Journal of clinical oncology, 页码:4276-4281 , 文章类型: Article,,卷期:2008年26-26]
- PurposeA small-cell lung carcinoma (SCLC) is found in 50% of patients with Lambert-Eaton myasthenic syndrome (LEMS). We evaluated screening to optimize screening strategy for SCLC. It is important to detect these tumors ...
- Spontaneous abortion in a Danish population-based cohort of childhood cancer survivors
[作者:Winther, JF; Boice, JD; Svendsen, AL; Frederiksen, K; Stovall, M; Olsen, JH,期刊:Journal of clinical oncology, 页码:4340-4346 , 文章类型: Article,,卷期:2008年26-26]
- PurposeRadiation induces germ-cell mutations in experimental animals that result in adverse pregnancy outcomes, as does uterine damage caused by high-dose radiotherapy. We assessed the risks for spontaneous abortion and ...
- Clinical and pathologic characteristics of patients with BRCA-positive and BRCA-negative breast cancer
[作者:Atchley, DP; Albarracin, CT; Lopez, A; Valero, V; Amos, CI; Gonzalez-Angulo, AM; Hortobagyi, GN; Arun, BK,期刊:Journal of clinical oncology, 页码:4282-4288 , 文章类型: Article,,卷期:2008年26-26]
- PurposeMutations in the BRCA1 and BRCA2 genes confer greater risk of developing breast cancer. We determined whether tumor pathologic features and clinical features differ in patients with and without BRCA mutations.Pati...
- Sudden psychotic symptoms in a 28-year-old male with thymoma
[作者:Gesundheit, B; Lerer, B; Budowski, E; Neuman, T; Gomori, JM; Or, R,期刊:Journal of clinical oncology, 页码:4353-4355 , 文章类型: Article,,卷期:2008年26-26]
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- Anaplastic large-cell lymphoma with leukemoid reaction
[作者:El-Osta, HE; Salyers, WJ; Palko, W; Hagan, ME; El-Haddad, B; Schulz, TK,期刊:Journal of clinical oncology, 页码:4356-4358 , 文章类型: Article,,卷期:2008年26-26]
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- Combination targeted therapy with sorafenib and bevacizumab results in enhanced toxicity and antitumor activity (vol 26, pg 3709, 2008)
[作者:Azad, NS; Posadas, EM; Kwitkowski, VE; Steinberg, SM; Jain, L; Annunziata, CM; Minasian, L; Sarosy, G; Kotz, HL; Premkumar, A; Cao, L; McNally, D; Chow, C; Chen, HX; Wright, JJ; Figg, WD; Kohn, EC,期刊:Journal of clinical oncology, 页码:4363-4363 , 文章类型: Correction,,卷期:2008年26-26]
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