- Plasma membrane-bound AGC3 kinases phosphorylate PIN auxin carriers at TPRXS(N/S) motifs to direct apical PIN recycling
[作者:Dhonukshe, P; Huang, F; Galvan-Ampudia, CS; Mahonen, AP; Kleine-Vehn, J; Xu, JA; Quint, A; Prasad, K; Friml, J; Scheres, B; Offringa, R,期刊:Development, 页码:3245-3255 , 文章类型: Article,,卷期:2010年137-19]
- Polar membrane cargo delivery is crucial for establishing cell polarity and for directional transport processes. In plants, polar trafficking mediates the dynamic asymmetric distribution of PIN FORMED (PIN) carriers, whi...
- The ubiquitin proteasome system is required for cell proliferation of the lens epithelium and for differentiation of lens fiber cells in zebrafish
[作者:Imai, F; Yoshizawa, A; Fujimori-Tonou, N; Kawakami, K; Masai, I,期刊:Development, 页码:3257-3268 , 文章类型: Article,,卷期:2010年137-19]
- In the developing vertebrate lens, epithelial cells differentiate into fiber cells, which are elongated and flat in shape and form a multilayered lens fiber core. In this study, we identified the zebrafish volvox (vov) m...
- Clonal analysis reveals common lineage relationships between head muscles and second heart field derivatives in the mouse embryo
[作者:Lescroart, F; Kelly, RG; Le Garrec, JF; Nicolas, JF; Meilhac, SM; Buckingham, M,期刊:Development, 页码:3269-3279 , 文章类型: Article,,卷期:2010年137-19]
- Head muscle progenitors in pharyngeal mesoderm are present in close proximity to cells of the second heart field and show overlapping patterns of gene expression. However, it is not clear whether a single progenitor cell...
- Mouse Emi2 as a distinctive regulatory hub in second meiotic metaphase
[作者:Suzuki, T; Suzuki, E; Yoshida, N; Kubo, A; Li, HM; Okuda, E; Amanai, M; Perry, ACF,期刊:Development, 页码:3281-3291 , 文章类型: Article,,卷期:2010年137-19]
- The oocytes of vertebrates are typically arrested at metaphase II (mII) by the cytostatic factor Emi2 until fertilization. Regulatory mechanisms in Xenopus Emi2 (xEmi2) are understood in detail but contrastingly little i...
- Anterior neural development requires Del1, a matrix-associated protein that attenuates canonical Wnt signaling via the Ror2 pathway
[作者:Takai, A; Inomata, H; Arakawa, A; Yakura, R; Matsuo-Takasaki, M; Sasai, Y,期刊:Development, 页码:3293-3302 , 文章类型: Article,,卷期:2010年137-19]
- During early embryogenesis, the neural plate is specified along the anterior-posterior (AP) axis by the action of graded patterning signals. In particular, the attenuation of canonical Wnt signals plays a central role in...
- Recognition of pre- and postsynaptic neurons via nephrin/NEPH1 homologs is a basis for the formation of the Drosophila retinotopic map
[作者:Sugie, A; Umetsu, D; Yasugi, T; Fischbach, KF; Tabata, T,期刊:Development, 页码:3303-3313 , 文章类型: Article,,卷期:2010年137-19]
- Topographic maps, which maintain the spatial order of neurons in the order of their axonal connections, are found in many parts of the nervous system. Here, we focus on the communication between retinal axons and their p...
- A genetic cascade involving klumpfuss, nab and castor specifies the abdominal leucokinergic neurons in the Drosophila CNS
[作者:Benito-Sipos, J; Estacio-Gomez, A; Moris-Sanz, M; Baumgardt, M; Thor, S; Diaz-Benjumea, FJ,期刊:Development, 页码:3327-3336 , 文章类型: Article,,卷期:2010年137-19]
- Identification of the genetic mechanisms underlying the specification of large numbers of different neuronal cell fates from limited numbers of progenitor cells is at the forefront of developmental neurobiology. In Droso...
- Drosophila Ataxin 2-binding protein 1 marks an intermediate step in the molecular differentiation of female germline cysts
[作者:Tastan, OY; Maines, JZ; Li, Y; Mckearin, DM; Buszczak, M,期刊:Development, 页码:3167-3176 , 文章类型: Article,,卷期:2010年137-19]
- In the Drosophila ovary, extrinsic signaling from the niche and intrinsic translational control machinery regulate the balance between germline stem cell maintenance and the differentiation of their daughters. However, t...
- miR-18, a member of Oncomir-1, targets heat shock transcription factor 2 in spermatogenesis
[作者:Bjork, JK; Sandqvist, A; Elsing, AN; Kotaja, N; Sistonen, L,期刊:Development, 页码:3177-3184 , 文章类型: Article,,卷期:2010年137-19]
- miR-18 belongs to the Oncomir-1 or miR-17 similar to 92 cluster that is intimately associated with the occurrence and progression of different types of cancer. However, the physiological roles of the Oncomir-1 cluster an...
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