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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共18条记录   Frizzled-5, a receptor for the synaptic organizer Wnt7a, regulates activity-mediated synaptogenesis [作者：Sahores, M; Gibb, A; Salinas, PC,期刊：Development, 页码：2215-2225 , 文章类型： Article，,卷期：2010年137-13] Wnt proteins play a crucial role in several aspects of neuronal circuit formation. Wnts can signal through different receptors including Frizzled, Ryk and Ror2. In the hippocampus, Wnt7a stimulates the formation of synap... Netrin-guided accessory cell morphogenesis dictates the dendrite orientation and migration of a Drosophila sensory neuron [作者：Mrkusich, EM; Osman, ZB; Bates, KE; Marchingo, JM; Duman-Scheel, M; Whitington, PM,期刊：Development, 页码：2227-2235 , 文章类型： Article，,卷期：2010年137-13] Accessory cells, which include glia and other cell types that develop in close association with neurons, have been shown to play key roles in regulating neuron development. However, the underlying molecular and cellular ... Nuclear pre-mRNA 3 '-end processing regulates synapse and axon development in C. elegans [作者：Van Epps, H; Dai, Y; Qi, YC; Goncharov, A; Jin, YS,期刊：Development, 页码：2237-2250 , 文章类型： Article，,卷期：2010年137-13] Nuclear pre-mRNA 3'-end processing is vital for the production of mature mRNA and the generation of the 3' untranslated region (UTR). However, the roles and regulation of this event in cellular development remain poorly ... An interview with Alex Joyner and Liz Robertson: Development editors at the helm of developmental biology societies [作者：Amsen, E; Joyner, A; Robertson, L,期刊：Development, 页码：2075-2077 , 文章类型： Editorial Material，,卷期：2010年137-13] Mechanism and evolution of cytosolic Hedgehog signal transduction [作者：Wilson, CW; Chuang, PT,期刊：Development, 页码：2079-2094 , 文章类型： Review，,卷期：2010年137-13] Hedgehog (Hh) signaling is required for embryonic patterning and postnatal physiology in invertebrates and vertebrates. With the revelation that the primary cilium is crucial for mammalian Hh signaling, the prevailing... Distinct functions of BMP4 during different stages of mouse ES cell neural commitment [作者：Zhang, KJ; Li, LY; Huang, CY; Shen, CY; Tan, FZ; Xia, CH; Liu, PY; Rossant, J; Jing, NH,期刊：Development, 页码：2095-2105 , 文章类型： Article，,卷期：2010年137-13] Bone morphogenetic protein (BMP) signaling plays a crucial role in maintaining the pluripotency of mouse embryonic stem cells (ESCs) and has negative effects on ESC neural differentiation. However, it remains unclear whe... The zebrafish flotte lotte mutant reveals that the local retinal environment promotes the differentiation of proliferating precursors emerging from their stem cell niche [作者：Cerveny, KL; Cavodeassi, F; Turner, KJ; de Jong-Curtain, TA; Heath, JK; Wilson, SW,期刊：Development, 页码：2107-2115 , 文章类型： Article，,卷期：2010年137-13] It is currently unclear how intrinsic and extrinsic mechanisms cooperate to control the progression from self-renewing to neurogenic divisions in retinal precursor cells. Here, we use the zebrafish flotte lotte (flo) mut... Specific roles of Target of rapamycin in the control of stem cells and their progeny in the Drosophila ovary [作者：LaFever, L; Feoktistov, A; Hsu, HJ; Drummond-Barbosa, D,期刊：Development, 页码：2117-2126 , 文章类型： Article，,卷期：2010年137-13] Stem cells depend on intrinsic and local factors to maintain their identity and activity, but they also sense and respond to changing external conditions. We previously showed that germline stem cells (GSCs) and follicle... Control of oligodendroglial cell number by the miR-17-92 cluster [作者：Budde, H; Schmitt, S; Fitzner, D; Opitz, L; Salinas-Riester, G; Simons, M,期刊：Development, 页码：2127-2132 , 文章类型： Article，,卷期：2010年137-13] The generation of myelinating cells in the central nervous system requires the initiation of specific gene expression programs in oligodendrocytes. We reasoned that microRNAs (miRNAs) could play an important role in this... MCAK regulates chromosome alignment but is not necessary for preventing aneuploidy in mouse oocyte meiosis I [作者：Illingworth, C; Pirmadjid, N; Serhal, P; Howe, K; FitzHarris, G,期刊：Development, 页码：2133-2138 , 文章类型： Article，,卷期：2010年137-13] Errors in chromosome segregation in mammalian oocytes lead to aneuploid eggs that are developmentally compromised. In mitotic cells, mitotic centromere associated kinesin (MCAK; KIF2C) prevents chromosome segregation err... Drosophila Tey represses transcription of the repulsive cue Toll and generates neuromuscular target specificity [作者：Inaki, M; Shinza-Kameda, M; Ismat, A; Frasch, M; Nose, A,期刊：Development, 页码：2139-2146 , 文章类型： Article，,卷期：2010年137-13] Little is known about the genetic program that generates synaptic specificity. Here we show that a putative transcription factor, Teyrha-Meyhra (Tey), controls target specificity, in part by repressing the expression of ... CARM1 is required for proper control of proliferation and differentiation of pulmonary epithelial cells [作者：O'Brien, KB; Alberich-Jorda, M; Yadav, N; Kocher, O; DiRuscio, A; Ebralidze, A; Levantini, E; Sng, NJL; Bhasin, M; Caron, T; Kim, D; Steidl, U; Huang, G; Halmos, B; Rodig, SJ; Bedford, MT; Tenen, DG; Kobayashi, S,期刊：Development, 页码：2147-2156 , 文章类型： Article，,卷期：2010年137-13] Coactivator-associated arginine methyltransferase I (CARM1; PRMT4) regulates gene expression by multiple mechanisms including methylation of histones and coactivation of steroid receptor transcription. Mice lacking CARM1... Drosophila acinus encodes a novel regulator of endocytic and autophagic trafficking [作者：Haberman, AS; Akbar, MA; Ray, S; Kramer, H,期刊：Development, 页码：2157-2166 , 文章类型： Article，,卷期：2010年137-13] Endosomal trafficking affects many cellular pathways from cell signaling to metabolism, but little is known about how these effects are coordinated. In a genetic screen for mutants affecting endosomal trafficking, we ide... Mesoderm migration in Drosophila is a multi-step process requiring FGF signaling and integrin activity [作者：McMahon, A; Reeves, GT; Supatto, W; Stathopoulos, A,期刊：Development, 页码：2167-2175 , 文章类型： Article，,卷期：2010年137-13] Migration is a complex, dynamic process that has largely been studied using qualitative or static approaches. As technology has improved, we can now take quantitative approaches towards understanding cell migration using... The Drosophila serine protease homologue Scarface regulates JNK signalling in a negative-feedback loop during epithelial morphogenesis [作者：Rousset, R; Bono-Lauriol, S; Gettings, M; Suzanne, M; Speder, P; Noselli, S,期刊：Development, 页码：2177-2186 , 文章类型： Article，,卷期：2010年137-13] In Drosophila melanogaster, dorsal closure is a model of tissue morphogenesis leading to the dorsal migration and sealing of the embryonic ectoderm. The activation of the JNK signal transduction pathway, specifically in ... Pulsatile shear and Gja5 modulate arterial identity and remodeling events during flow-driven arteriogenesis [作者：Buschmann, I; Pries, A; Styp-Rekowska, B; Hillmeister, P; Loufrani, L; Henrion, D; Shi, Y; Duelsner, A; Hoefer, I; Gatzke, N; Wang, HT; Lehmann, K; Ulm, L; Ritter, Z; Hauff, P; Hlushchuk, R; Djonov, V; van Veen, T; Le Noble, F,期刊：Development, 页码：2187-2196 , 文章类型： Article，,卷期：2010年137-13] In the developing chicken embryo yolk sac vasculature, the expression of arterial identity genes requires arterial hemodynamic conditions. We hypothesize that arterial flow must provide a unique signal that is relevant f...