- Temporal specification of blood progenitors from mouse embryonic stem cells and induced pluripotent stem cells
[作者:Irion, S; Clarke, RL; Luche, H; Kim, I; Morrison, SJ; Fehling, HJ; Keller, GM,期刊:Development, 页码:2829-2839 , 文章类型: Article,,卷期:2010年137-17]
- The efficient and reproducible generation of differentiated progenitors from pluripotent stem cells requires the recapitulation of appropriate developmental stages and pathways. Here, we have used the combination of acti...
- The control of axillary meristem fate in the maize ramosa pathway
[作者:Gallavotti, A; Long, JA; Stanfield, S; Yang, XA; Jackson, D; Vollbrecht, E; Schmidt, RJ,期刊:Development, 页码:2849-2856 , 文章类型: Article,,卷期:2010年137-17]
- Plant axillary meristems are composed of highly organized, self-renewing stem cells that produce indeterminate branches or terminate in differentiated structures, such as the flowers. These opposite fates, dictated by bo...
- Transcriptomic landscape of the primitive streak
[作者:Alev, C; Wu, YP; Kasukawa, T; Jakt, LM; Ueda, HR; Sheng, GJ,期刊:Development, 页码:2863-2874 , 文章类型: Article,,卷期:2010年137-17]
- In birds and mammals, all mesoderm cells are generated from the primitive streak. Nascent mesoderm cells contain unique dorsoventral (D/V) identities according to their relative ingression position along the streak. Mole...
- Hfp inhibits Drosophila myc transcription and cell growth in a TFIIH/Hay-dependent manner
[作者:Mitchell, NC; Johanson, TM; Cranna, NJ; Er, ALJ; Richardson, HE; Hannan, RD; Quinn, LM,期刊:Development, 页码:2875-2884 , 文章类型: Article,,卷期:2010年137-17]
- An unresolved question regarding the RNA-recognition motif (RRM) protein Half pint (Hfp) has been whether its tumour suppressor behaviour occurs by a transcriptional mechanism or via effects on splicing. The data present...
- Pph13 and Orthodenticle define a dual regulatory pathway for photoreceptor cell morphogenesis and function
[作者:Mishra, M; Oke, A; Lebel, C; McDonald, EC; Plummer, Z; Cook, TA; Zelhof, AC,期刊:Development, 页码:2895-2904 , 文章类型: Article,,卷期:2010年137-17]
- The function and integrity of photoreceptor cells are dependent upon the creation and maintenance of specialized apical structures: membrane discs/outer segments in vertebrates and rhabdomeres in insects. We performed a ...
- Strigolactones enhance competition between shoot branches by dampening auxin transport
[作者:Crawford, S; Shinohara, N; Sieberer, T; Williamson, L; George, G; Hepworth, J; Muller, D; Domagalska, MA; Leyser, O,期刊:Development, 页码:2905-2913 , 文章类型: Article,,卷期:2010年137-17]
- Strigolactones (SLs), or their derivatives, were recently demonstrated to act as endogenous shoot branching inhibitors, but their biosynthesis and mechanism of action are poorly understood. Here we show that the branchin...
- H3K27me3 regulates BMP activity in developing spinal cord
[作者:Akizu, N; Estaras, C; Guerrero, L; Marti, E; Martinez-Balbas, MA,期刊:Development, 页码:2915-2925 , 文章类型: Article,,卷期:2010年137-17]
- During spinal cord development, the combination of secreted signaling proteins and transcription factors provides information for each neural type differentiation. Studies using embryonic stem cells show that trimethylat...
- The same enhancer regulates the earliest Emx2 expression in caudal forebrain primordium, subsequent expression in dorsal telencephalon and later expression in the cortical ventricular zone
[作者:Suda, Y; Kokura, K; Kimura, J; Kajikawa, E; Inoue, F; Aizawa, S,期刊:Development, 页码:2939-2949 , 文章类型: Article,,卷期:2010年137-17]
- We have analyzed Emx2 enhancers to determine how Emx2 functions during forebrain development are regulated. The FB (forebrain) enhancer we identified immediately 3' downstream of the last coding exon is well conserved am...
- Developmental RNA processing of 3 ' UTRs in Hox mRNAs as a context-dependent mechanism modulating visibility to microRNAs
[作者:Thomsen, S; Azzam, G; Kaschula, R; Williams, LS; Alonso, CR,期刊:Development, 页码:2951-2960 , 文章类型: Article,,卷期:2010年137-17]
- The Drosophila Hox gene Ultrabithorax (Ubx) controls the development of thoracic and abdominal segments, allocating segment-specific features to different cell lineages. Recent studies have shown that Ubx expression is p...
- The occipital lateral plate mesoderm is a novel source for vertebrate neck musculature
[作者:Theis, S; Patel, K; Valasek, P; Otto, A; Pu, Q; Harel, I; Tzahor, E; Tajbakhsh, S; Christ, B; Huang, RJ,期刊:Development, 页码:2961-2971 , 文章类型: Article,,卷期:2010年137-17]
- In vertebrates, body musculature originates from somites, whereas head muscles originate from the cranial mesoderm. Neck muscles are located in the transition between these regions. We show that the chick occipital later...
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