- Compendium of Unpublished Phase III Trials in Oncology: Characteristics and Impact on Clinical Practice
[作者:Tam, VC; Tannock, IF; Massey, C; Rauw, J; Krzyzanowska, MK,期刊:Journal of clinical oncology, 页码:3133-3139 , 文章类型: Article,,卷期:2011年29-23]
- Purpose Many phase III trials presented at annual meetings of the American Society of Clinical Oncology (ASCO) remain unpublished. The results of these unpublished trials, if more generally known, might have an impact on...
- Documenting the Natural History of Patients With Resected Stage II Adenocarcinoma of the Colon After Random Assignment to Adjuvant Treatment With Edrecolomab or Observation: Results From CALGB 9581
[作者:Niedzwiecki, D; Bertagnolli, MM; Warren, RS; Compton, CC; Kemeny, NE; Benson, AB; Eckhardt, SG; Alberts, S; Porjosh, GN; Kerr, DJ; Fields, A; Rougier, P; Pipas, JM; Schwartz, JH; Atkins, J; O'Rourke, M; Perry, MC; Goldberg, RM; Mayer, RJ; Colacchio, TA,期刊:Journal of clinical oncology, 页码:3146-3152 , 文章类型: Article,,卷期:2011年29-23]
- Purpose We conducted a randomized trial comparing adjuvant treatment with edrecolomab versus observation in patients with resected, low-risk, stage II colon cancer. This study also prospectively studied patient-and tumor...
- Fatal Infusion Reaction to Cetuximab: The Need for Predictive Risk Factors and Safer Patient Selection
[作者:Tronconi, MC; Sclafani, F; Rimassa, L; Carnaghi, C; Personeni, N; Santoro, A,期刊:Journal of clinical oncology, 页码:E680-E681 , 文章类型: Editorial Material,,卷期:2011年29-23]
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- Microsatellite Instability and Loss of Heterozygosity at Chromosomal Location 18q: Prospective Evaluation of Biomarkers for Stages II and III Colon Cancer-A Study of CALGB 9581 and 89803
[作者:Bertagnolli, MM; Redston, M; Compton, CC; Niedzwiecki, D; Mayer, RJ; Goldberg, RM; Colacchio, TA; Saltz, LB; Warren, RS,期刊:Journal of clinical oncology, 页码:3153-3162 , 文章类型: Article,,卷期:2011年29-23]
- Purpose Colorectal cancer (CRC) develops as a result of a series of accumulated genomic changes that produce oncogene activation and tumor suppressor gene loss. These characteristics may classify CRC into subsets of dist...
- Multiple Osteolytic Bone Lesions 3 Years After Ovarian Cancer: Benign or Malignant?
[作者:Guo, JJ; Liu, W; Yang, HL; Qian, HX; Tang, TS; Qin, L,期刊:Journal of clinical oncology, 页码:E672-E674 , 文章类型: Editorial Material,,卷期:2011年29-23]
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- Mutations and Deletions of the TP53 Gene Predict Nonresponse to Treatment and Poor Outcome in First Relapse of Childhood Acute Lymphoblastic Leukemia
[作者:Hof, J; Krentz, S; van Schewick, C; Korner, G; Shalapour, S; Rhein, P; Karawajew, L; Ludwig, WD; Seeger, K; Henze, G; von Stackelberg, A; Hagemeier, C; Eckert, C; Kirschner-Schwabe, R,期刊:Journal of clinical oncology, 页码:3185-3193 , 文章类型: Article; Proceedings Paper,,卷期:2011年29-23]
- Purpose In the clinical management of children with relapsed acute lymphoblastic leukemia (ALL), treatment resistance remains a major challenge. Alterations of the TP53 gene are frequently associated with resistance to c...
- Phase I/II Study of Trastuzumab in Combination With Everolimus (RAD001) in Patients With HER2-Overexpressing Metastatic Breast Cancer Who Progressed on Trastuzumab-Based Therapy
[作者:Morrow, PK; Wulf, GM; Ensor, J; Booser, DJ; Moore, JA; Flores, PR; Xiong, Y; Zhang, SY; Krop, IE; Winer, EP; Kindelberger, DW; Coviello, J; Sahin, AA; Nunez, R; Hortobagyi, GN; Yu, DH; Esteva, FJ,期刊:Journal of clinical oncology, 页码:3126-3132 , 文章类型: Article,,卷期:2011年29-23]
- Purpose Trastuzumab resistance has been linked to activation of the phosphoinositol 3-kinase (PI3K) pathway. Phosphatase and tensin homolog (PTEN) is a dual phosphatase that counteracts the PI3K function; PTEN loss leads...
- Human Epidermal Growth Factor Eyedrops for Cetuximab-Related Filamentary Keratitis
[作者:Kawakami, H; Sugioka, K; Yonesaka, K; Satoh, T; Shimomura, Y; Nakagawa, K,期刊:Journal of clinical oncology, 页码:E678-E679 , 文章类型: Editorial Material,,卷期:2011年29-23]
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- Impact of Treatment End Point Definitions on Perceived Differences in Long-Term Outcome With Tyrosine Kinase Inhibitor Therapy in Chronic Myeloid Leukemia
[作者:Kantarjian, H; O'Brien, S; Jabbour, E; Shan, J; Ravandi, F; Kadia, T; Faderl, S; Garcia-Manero, G; Borthakur, G; Cortes, J,期刊:Journal of clinical oncology, 页码:3173-3178 , 文章类型: Article,,卷期:2011年29-23]
- Purpose Different definitions of progression-free survival (PFS) and event-free survival (EFS) may result in perceived differences in outcomes with tyrosine kinase inhibitor (TKI) therapies in chronic myelogenous leukemi...
- Nomograms for Predicting Local Recurrence, Distant Metastases, and Overall Survival for Patients With Locally Advanced Rectal Cancer on the Basis of European Randomized Clinical Trials
[作者:Valentini, V; van Stiphout, RGPM; Lammering, G; Gambacorta, MA; Barba, MC; Bebenek, M; Bonnetain, F; Bosset, JF; Bujko, K; Cionini, L; Gerard, JP; Rodel, C; Sainato, A; Sauer, R; Minsky, BD; Collette, L; Lambin, P,期刊:Journal of clinical oncology, 页码:3163-3172 , 文章类型: Article,,卷期:2011年29-23]
- Purpose The purpose of this study was to develop accurate models and nomograms to predict local recurrence, distant metastases, and survival for patients with locally advanced rectal cancer treated with long-course chemo...
- Increase of Ascites and Pleural Effusion Misleading Assessment of Antitumor Response to Erlotinib in Adenocarcinoma of the Lung
[作者:Tachihara, M; Misa, K; Uematsu, M; Minemura, H; Katsuura, Y; Ishida, T; Munakata, M,期刊:Journal of clinical oncology, 页码:E675-E677 , 文章类型: Editorial Material,,卷期:2011年29-23]
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- Intrahepatic Cholangiocarcinoma: An International Multi-Institutional Analysis of Prognostic Factors and Lymph Node Assessment
[作者:de Jong, MC; Nathan, H; Sotiropoulos, GC; Paul, A; Alexandrescu, S; Marques, H; Pulitano, C; Barroso, E; Clary, BM; Aldrighetti, L; Ferrone, CR; Zhu, AX; Bauer, TW; Walters, DM; Gamblin, TC; Nguyen, KT; Turley, R; Popescu, I; Hubert, C; Meyer, S; Schulick, RD; Choti, MA; Gigot, JF; Mentha, G; Pawlik, TM,期刊:Journal of clinical oncology, 页码:3140-3145 , 文章类型: Article,,卷期:2011年29-23]
- Purpose To identify factors associated with outcome after surgical management of intrahepatic cholangio-carcinoma (ICC) and examine the impact of lymph node (LN) assessment on survival. Patients and Methods From an inter...
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