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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共20条记录   Fifty years of X-inactivation research [作者：Gendrel, AV; Heard, E,期刊：Development, 页码：5049-5055 , 文章类型： Editorial Material，,卷期：2011年138-23] The third X-inactivation meeting 'Fifty years of X-inactivation research', which celebrated the fiftieth anniversary of Mary Lyon's formulation of the X-inactivation hypothesis, was an EMBO workshop held in Oxford, UK, i... Chromosome silencing mechanisms in X-chromosome inactivation: unknown unknowns [作者：Brockdorff, N,期刊：Development, 页码：5057-5065 , 文章类型： Review，,卷期：2011年138-23] Fifty years ago, Mary Lyon hypothesised that one of the two X chromosomes in female mammalian cells is inactivated at random during early embryogenesis and that the inactive X is then stably maintained through all subseq... The role of Pax6 in regulating the orientation and mode of cell division of progenitors in the mouse cerebral cortex [作者：Asami, M; Pilz, GA; Ninkovic, J; Godinho, L; Schroeder, T; Huttner, WB; Gotz, M,期刊：Development, 页码：5067-5078 , 文章类型： Article，,卷期：2011年138-23] Successful brain development requires tight regulation of sequential symmetric and asymmetric cell division. Although Pax6 is known to exert multiple roles in the developing nervous system, its role in the regulation of ... String (Cdc25) regulates stem cell maintenance, proliferation and aging in Drosophila testis [作者：Inaba, M; Yuan, HB; Yamashita, YM,期刊：Development, 页码：5079-5086 , 文章类型： Article，,卷期：2011年138-23] Tight regulation of stem cell proliferation is fundamental to tissue homeostasis, aging and tumor suppression. Although stem cells are characterized by their high potential to proliferate throughout the life of the organ... Self-maintained escort cells form a germline stem cell differentiation niche [作者：Kirilly, D; Wang, S; Xie, T,期刊：Development, 页码：5087-5097 , 文章类型： Article，,卷期：2011年138-23] Stem cell self-renewal is controlled by concerted actions of niche signals and intrinsic factors in a variety of systems. In the Drosophila ovary, germline stem cells (GSCs) in the niche continuously self-renew and gener... FGF/EGF signaling regulates the renewal of early nephron progenitors during embryonic development [作者：Brown, AC; Adams, D; de Caestecker, M; Yang, XH; Friesel, R; Oxburgh, L,期刊：Development, 页码：5099-5112 , 文章类型： Article，,卷期：2011年138-23] Recent studies indicate that nephron progenitor cells of the embryonic kidney are arranged in a series of compartments of an increasing state of differentiation. The earliest progenitor compartment, distinguished by expr... Hedgehog and retinoic acid signaling cooperate to promote motoneurogenesis in zebrafish [作者：Mich, JK; Chen, JK,期刊：Development, 页码：5113-5119 , 文章类型： Article，,卷期：2011年138-23] The precise requirements of Hedgehog (Hh) pathway activity in vertebrate central nervous system development remain unclear, particularly in organisms with both maternally and zygotically derived signaling. Here we descri... Roles of Hedgehog pathway components and retinoic acid signalling in specifying zebrafish ventral spinal cord neurons [作者：England, S; Batista, MF; Mich, JK; Chen, JK; Lewis, KE,期刊：Development, 页码：5121-5134 , 文章类型： Article，,卷期：2011年138-23] In mouse, Hedgehog (Hh) signalling is required for most ventral spinal neurons to form. Here, we analyse the spinal cord phenotype of zebrafish maternal-zygotic smoothened (MZsmo) mutants that completely lack Hh signalli... Combinatorial roles for BMPs and Endothelin 1 in patterning the dorsal-ventral axis of the craniofacial skeleton [作者：Alexander, C; Zuniga, E; Blitz, IL; Wada, N; Le Pabic, P; Javidan, Y; Zhang, TL; Cho, KW; Crump, JG; Schilling, TF,期刊：Development, 页码：5135-5146 , 文章类型： Article，,卷期：2011年138-23] Bone morphogenetic proteins (BMPs) play crucial roles in craniofacial development but little is known about their interactions with other signals, such as Endothelin 1 (Edn1) and Jagged/Notch, which pattern the dorsal-ve... Gremlin 2 regulates distinct roles of BMP and Endothelin 1 signaling in dorsoventral patterning of the facial skeleton [作者：Zuniga, E; Rippen, M; Alexander, C; Schilling, TF; Crump, JG,期刊：Development, 页码：5147-5156 , 文章类型： Article，,卷期：2011年138-23] Patterning of the upper versus lower face involves generating distinct pre-skeletal identities along the dorsoventral (DV) axes of the pharyngeal arches. Whereas previous studies have shown roles for BMPs, Endothelin 1 (... The astrocyte-expressed integrin alpha v beta 8 governs blood vessel sprouting in the developing retina [作者：Hirota, S; Liu, Q; Lee, HS; Hossain, MG; Lacy-Hulbert, A; McCarty, JH,期刊：Development, 页码：5157-5166 , 文章类型： Article，,卷期：2011年138-23] The mouse retina is vascularized after birth when angiogenic blood vessels grow and sprout along a pre-formed latticework of astrocytes. How astrocyte-derived cues control patterns of blood vessel growth and sprouting, h... A novel role for the floral homeotic gene APETALA2 during Arabidopsis fruit development [作者：Ripoll, JJ; Roeder, AHK; Ditta, GS; Yanofsky, MF,期刊：Development, 页码：5167-5176 , 文章类型： Article，,卷期：2011年138-23] The majority of the Arabidopsis fruit comprises an ovary with three primary tissue types: the valves, the replum and the valve margins. The valves, which are derived from the ovary walls, are separated along their entire... A Trio-RhoA-Shroom3 pathway is required for apical constriction and epithelial invagination [作者：Plageman, TF; Chauhan, BK; Yang, C; Jaudon, F; Shang, X; Zheng, Y; Lou, M; Debant, A; Hildebrand, JD; Lang, RA,期刊：Development, 页码：5177-5188 , 文章类型： Article，,卷期：2011年138-23] Epithelial invagination is a common feature of embryogenesis. An example of invagination morphogenesis occurs during development of the early eye when the lens placode forms the lens pit. This morphogenesis is accompanie... Reprogramming adult dermis to a neonatal state through epidermal activation of beta-catenin [作者：Collins, CA; Kretzschmar, K; Watt, FM,期刊：Development, 页码：5189-5199 , 文章类型： Article，,卷期：2011年138-23] Hair follicle formation depends on reciprocal epidermal-dermal interactions and occurs during skin development, but not in adult life. This suggests that the properties of dermal fibroblasts change during postnatal devel... Regulation of Drosophila glial cell proliferation by Merlin-Hippo signaling [作者：Reddy, BVVG; Irvine, KD,期刊：Development, 页码：5201-5212 , 文章类型： Article，,卷期：2011年138-23] Glia perform diverse and essential roles in the nervous system, but the mechanisms that regulate glial cell numbers are not well understood. Here, we identify and characterize a requirement for the Hippo pathway and its ... Retinoic acid-dependent and -independent gene-regulatory pathways of Pitx3 in meso-diencephalic dopaminergic neurons [作者：Jacobs, FMJ; Veenvliet, JV; Almirza, WH; Hoekstra, EJ; von Oerthel, L; van der Linden, AJA; Neijts, R; Koerkamp, MG; van Leenen, D; Holstege, FCP; Burbach, JPH; Smidt, MP,期刊：Development, 页码：5213-5222 , 文章类型： Article，,卷期：2011年138-23] Development of meso-diencephalic dopamine (mdDA) neurons requires the combined actions of the orphan nuclear receptor Nurr1 and the paired-like homeobox transcription factor Pitx3. Whereas all mdDA neurons require Nurr1 ...