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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共21条记录   Modeling new conceptual interpretations of development [作者：Vermot, J; Affolter, M,期刊：Development, 页码：4111-4115 , 文章类型： Review，,卷期：2011年138-19] In April 2011, researchers from diverse background met at the Gulbenkian Institute (Oeiras, Portugal) to discuss the emerging input of biophysics into the field of developmental biology. The scope of the workshop was to ... The control of developmental phase transitions in plants [作者：Huijser, P; Schmid, M,期刊：Development, 页码：4117-4129 , 文章类型： Review，,卷期：2011年138-19] Plant development progresses through distinct phases: vegetative growth, followed by a reproductive phase and eventually seed set and senescence. The transitions between these phases are controlled by distinct genetic ci... Activin and GDF11 collaborate in feedback control of neuroepithelial stem cell proliferation and fate [作者：Gokoffski, KK; Wu, HH; Beites, CL; Kim, J; Kim, EJ; Matzuk, MM; Johnson, JE; Lander, AD; Calof, AL,期刊：Development, 页码：4131-4142 , 文章类型： Article，,卷期：2011年138-19] Studies of the olfactory epithelium model system have demonstrated that production of neurons is regulated by negative feedback. Previously, we showed that a locally produced signal, the TGF beta superfamily ligand GDF11... HNF4A is essential for specification of hepatic progenitors from human pluripotent stem cells [作者：DeLaForest, A; Nagaoka, M; Si-Tayeb, K; Noto, FK; Konopka, G; Battle, MA; Duncan, SA,期刊：Development, 页码：4143-4153 , 文章类型： Article，,卷期：2011年138-19] The availability of pluripotent stem cells offers the possibility of using such cells to model hepatic disease and development. With this in mind, we previously established a protocol that facilitates the differentiation... LGN-dependent orientation of cell divisions in the dermomyotome controls lineage segregation into muscle and dermis [作者：Ben-Yair, R; Kahane, N; Kalcheim, C,期刊：Development, 页码：4155-4166 , 文章类型： Article，,卷期：2011年138-19] The plane of cell divisions is pivotal for differential fate acquisition. Dermomyotome development provides an excellent system with which to investigate the link between these processes. In the central sheet of the earl... Gcm/Glide-dependent conversion into glia depends on neural stem cell age, but not on division, triggering a chromatin signature that is conserved in vertebrate glia [作者：Flici, H; Erkosar, B; Komonyi, O; Karatas, OF; Laneve, P; Giangrande, A,期刊：Development, 页码：4167-4178 , 文章类型： Article，,卷期：2011年138-19] Neurons and glia differentiate from multipotent precursors called neural stem cells (NSCs), upon the activation of specific transcription factors. In vitro, it has been shown that NSCs display very plastic features; howe... Secreted frizzled-related proteins are required for Wnt/beta-catenin signalling activation in the vertebrate optic cup [作者：Esteve, P; Sandonis, A; Ibanez, C; Shimono, A; Guerrero, I; Bovolenta, P,期刊：Development, 页码：4179-4184 , 文章类型： Article，,卷期：2011年138-19] Secreted frizzled-related proteins (Sfrps) are considered Wnt signalling antagonists but recent studies have shown that specific family members enhance Wnt diffusion and thus positively modulate Wnt signalling. Whether t... The cytoplasmic domain of neuropilin 1 is dispensable for angiogenesis, but promotes the spatial separation of retinal arteries and veins [作者：Fantin, A; Schwarz, Q; Davidson, K; Normando, EM; Denti, L; Ruhrberg, C,期刊：Development, 页码：4185-4191 , 文章类型： Article，,卷期：2011年138-19] Neuropilin 1 (NRP1) is a transmembrane glycoprotein that is essential for blood vessel development in vertebrates. Best known for its ability to bind members of the vascular endothelial growth factor (VEGF) and class 3 s... Transmembrane protein 2 (Tmem2) is required to regionally restrict atrioventricular canal boundary and endocardial cushion development [作者：Smith, KA; Lagendijk, AK; Courtney, AD; Chen, HJ; Paterson, S; Hogan, BM; Wicking, C; Bakkers, J,期刊：Development, 页码：4193-4198 , 文章类型： Article，,卷期：2011年138-19] The atrioventricular canal (AVC) physically separates the atrial and ventricular chambers of the heart and plays a crucial role in the development of the valves and septa. Defects in AVC development result in aberrant he... The novel transmembrane protein Tmem2 is essential for coordination of myocardial and endocardial morphogenesis [作者：Totong, R; Schell, T; Lescroart, F; Ryckebusch, L; Lin, YF; Zygmunt, T; Herwig, L; Krudewig, A; Gershoony, D; Belting, HG; Affolter, M; Torres-Vazquez, J; Yelon, D,期刊：Development, 页码：4199-4205 , 文章类型： Article，,卷期：2011年138-19] Coordination between adjacent tissues plays a crucial role during the morphogenesis of developing organs. In the embryonic heart, two tissues - the myocardium and the endocardium - are closely juxtaposed throughout their... HP1 gamma links histone methylation marks to meiotic synapsis in mice [作者：Takada, Y; Naruse, C; Costa, Y; Shirakawa, T; Tachibana, M; Sharif, J; Kezuka-Shiotani, F; Kakiuchi, D; Masumoto, H; Shinkai, Y; Ohbo, K; Peters, AHFM; Turner, JMA; Asano, M; Koseki, H,期刊：Development, 页码：4207-4217 , 文章类型： Article，,卷期：2011年138-19] During meiosis, specific histone modifications at pericentric heterochromatin (PCH), especially histone H3 tri- and dimethylation at lysine 9 (H3K9me3 and H3K9me2, respectively), are required for proper chromosome intera... The Hedgehog-induced Smoothened conformational switch assembles a signaling complex that activates Fused by promoting its dimerization and phosphorylation [作者：Shi, Q; Li, S; Jia, JH; Jiang, J,期刊：Development, 页码：4219-4231 , 文章类型： Article，,卷期：2011年138-19] Hedgehog (Hh) transduces signal by regulating the subcellular localization and conformational state of the GPCR-like protein Smoothened (Smo) but how Smo relays the signal to cytoplasmic signaling components remains poor... Fez function is required to maintain the size of the animal plate in the sea urchin embryo [作者：Yaguchi, S; Yaguchi, J; Wei, Z; Jin, YH; Angerer, LM; Inaba, K,期刊：Development, 页码：4233-4243 , 文章类型： Article，,卷期：2011年138-19] Partitioning ectoderm precisely into neurogenic and non-neurogenic regions is an essential step for neurogenesis of almost all bilaterian embryos. Although it is widely accepted that antagonism between BMP and its inhibi... Notch pathway activation can replace the requirement for Wnt4 and Wnt9b in mesenchymal-to-epithelial transition of nephron stem cells [作者：Boyle, SC; Kim, M; Valerius, MT; McMahon, AP; Kopan, R,期刊：Development, 页码：4245-4254 , 文章类型： Article，,卷期：2011年138-19] The primary excretory organ in vertebrates is the kidney, which is responsible for blood filtration, solute homeostasis and pH balance. These functions are carried out by specialized epithelial cells organized into tubul... Distinct and mutually inhibitory binding by two divergent. beta-catenins coordinates TCF levels and activity in C-elegans [作者：Yang, XD; Huang, SY; Lo, MC; Mizumoto, K; Sawa, H; Xu, WQ; Robertson, S; Lin, RL,期刊：Development, 页码：4255-4265 , 文章类型： Article，,卷期：2011年138-19] Wnt target gene activation in C. elegans requires simultaneous elevation of. beta-catenin/SYS-1 and reduction of TCF/POP-1 nuclear levels within the same signal-responsive cell. SYS-1 binds to the conserved N-terminal. b... Cell cycle-regulated multi-site phosphorylation of Neurogenin 2 coordinates cell cycling with differentiation during neurogenesis [作者：Ali, F; Hindley, C; McDowell, G; Deibler, R; Jones, A; Kirschner, M; Guillemot, F; Philpott, A,期刊：Development, 页码：4267-4277 , 文章类型： Article，,卷期：2011年138-19] During development of the central nervous system, the transition from progenitor maintenance to differentiation is directly triggered by a lengthening of the cell cycle that occurs as development progresses. However, the...