- Activin/Nodal Signaling Controls Divergent Transcriptional Networks in Human Embryonic Stem Cells and in Endoderm Progenitors
[作者:Brown, S; Teo, A; Pauklin, S; Hannan, N; Cho, CHH; Lim, B; Vardy, L; Dunn, NR; Trotter, M; Pedersen, R; Vallier, L,期刊:Stem Cells, 页码:1176-1185 , 文章类型: Article,,卷期:2011年29-8]
- Activin/Nodal signaling is necessary to maintain pluripotency of human embryonic stem cells (hESCs) and to induce their differentiation toward endoderm. However, the mechanisms by which Activin/Nodal signaling achieves t...
- Complete Meiosis from Human Induced Pluripotent Stem Cells
[作者:Eguizabal, C; Montserrat, N; Vassena, R; Barragan, M; Garreta, E; Garcia-Quevedo, L; Vidal, F; Giorgetti, A; Veiga, A; Belmonte, JCI,期刊:Stem Cells, 页码:1186-1195 , 文章类型: Article,,卷期:2011年29-8]
- Gamete failure-derived infertility affects millions of people worldwide; for many patients, gamete donation by unrelated donors is the only available treatment. Embryonic stem cells (ESCs) can differentiate in vitro into...
- CC Chemokine Ligand 2 and Leukemia Inhibitory Factor Cooperatively Promote Pluripotency in Mouse Induced Pluripotent Cells
[作者:Hasegawa, Y; Takahashi, N; Forrest, ARR; Shin, JW; Kinoshita, Y; Suzuki, H; Hayashizaki, Y,期刊:Stem Cells, 页码:1196-1205 , 文章类型: Article,,卷期:2011年29-8]
- The pluripotency of mouse embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) can be maintained by feeder cells, which secrete leukemia inhibitory factor (LIF). We found that feeder cells provide a rel...
- Optic Vesicle-like Structures Derived from Human Pluripotent Stem Cells Facilitate a Customized Approach to Retinal Disease Treatment
[作者:Meyer, JS; Howden, SE; Wallace, KA; Verhoeven, AD; Wright, LS; Capowski, EE; Pinilla, I; Martin, JM; Tian, SL; Stewart, R; Pattnaik, B; Thomson, JA; Gamm, DM,期刊:Stem Cells, 页码:1206-1218 , 文章类型: Article,,卷期:2011年29-8]
- Differentiation methods for human induced pluripotent stem cells (hiPSCs) typically yield progeny from multiple tissue lineages, limiting their use for drug testing and autologous cell transplantation. In particular, ear...
- Debrided Skin as a Source of Autologous Stem Cells for Wound Repair
[作者:Natesan, S; Wrice, NL; Baer, DG; Christy, RJ,期刊:Stem Cells, 页码:1219-1230 , 文章类型: Article,,卷期:2011年29-8]
- Major traumatic injuries to the body, such as large surface area burns, limit the availability of autologous stem cell populations for wound repair. This report demonstrates that even after severe burn trauma to the body...
- Genetically Encoding Unnatural Amino Acids in Neural Stem Cells and Optically Reporting Voltage-Sensitive Domain Changes in Differentiated Neurons
[作者:Shen, B; Xiang, Z; Miller, B; Louie, G; Wang, WY; Noel, JP; Gage, FH; Wang, L,期刊:Stem Cells, 页码:1231-1240 , 文章类型: Article,,卷期:2011年29-8]
- Although unnatural amino acids (Uaas) have been genetically encoded in bacterial, fungal, and mammalian cells using orthogonal transfer RNA (tRNA)/aminoacyl-tRNA synthetase pairs, applications of this method to a wider r...
- Dura Mater Stimulates Human Adipose-Derived Stromal Cells to Undergo Bone Formation in Mouse Calvarial Defects
[作者:Levi, B; Nelson, ER; Li, SL; James, AW; Hyun, JS; Montoro, DT; Lee, M; Glotzbach, JP; Commons, GW; Longaker, MT,期刊:Stem Cells, 页码:1241-1255 , 文章类型: Article,,卷期:2011年29-8]
- Human adipose-derived stromal cells (hASCs) have a proven capacity to aid in osseous repair of calvarial defects. However, the bone defect microenvironment necessary for osseous healing is not fully understood. In this s...
- Functional Characterization of Quiescent Keratinocyte Stem Cells and Their Progeny Reveals a Hierarchical Organization in Human Skin Epidermis
[作者:Schluter, H; Paquet-Fifield, S; Gangatirkar, P; Li, J; Kaur, P,期刊:Stem Cells, 页码:1256-1268 , 文章类型: Article,,卷期:2011年29-8]
- Although homeostatic renewal of human skin epidermis is achieved by the combined activity of quiescent stem cells (SCs) and their actively cycling progeny, whether these two populations are equipotent in their capacity t...
- Geminin Regulates Cortical Progenitor Proliferation and Differentiation
[作者:Spella, M; Kyrousi, C; Kritikou, E; Stathopoulou, A; Guillemot, F; Kioussis, D; Pachnis, V; Lygerou, Z; Taraviras, S,期刊:Stem Cells, 页码:1269-1282 , 文章类型: Article,,卷期:2011年29-8]
- During cortical development, coordination of proliferation and differentiation ensures the timely generation of different neural progenitor lineages that will give rise to mature neurons and glia. Geminin is an inhibitor...
- Novel Stem/Progenitor Cell Population from Murine Tracheal Submucosal Gland Ducts with Multipotent Regenerative Potential
[作者:Hegab, AE; Ha, VL; Gilbert, JL; Zhang, KX; Malkoski, SP; Chon, AT; Darmawan, DO; Bisht, B; Ooi, AT; Pellegrini, M; Nickerson, DW; Gomperts, BN,期刊:Stem Cells, 页码:1283-1293 , 文章类型: Article,,卷期:2011年29-8]
- The airway epithelium is in direct contact with the environment and therefore constantly at risk for injury. Basal cells (BCs) have been found to repair the surface epithelium (SE), but the contribution of other stem cel...
- Bone Marrow Stromal Cells Produce Long-Term Pain Relief in Rat Models of Persistent Pain
[作者:Guo, W; Wang, H; Zou, SP; Gu, M; Watanabe, M; Wei, F; Dubner, R; Huang, GTJ; Ren, K,期刊:Stem Cells, 页码:1294-1303 , 文章类型: Article,,卷期:2011年29-8]
- Chronic pain conditions are difficult to treat and are major health problems. Bone marrow stromal cells (BMSCs) have generated considerable interest as a candidate for cell-based therapy. BMSCs are readily accessible and...
- Brief Report: Evaluating the Potential of Putative Pluripotent Cells Derived from Human Testis
[作者:Ko, K; Reinhardt, P; Tapia, N; Schneider, RK; Arauzo-Bravo, MJ; Han, DW; Greber, B; Kim, J; Kliesch, S; Zenke, M; Scholer, HR,期刊:Stem Cells, 页码:1304-1309 , 文章类型: Article,,卷期:2011年29-8]
- Human adult germline stem cells (haGSCs) were established from human testicular biopsies and were claimed to be pluripotent. Recently, the gene expression profile of haGSCs demonstrated that these cells presented with a ...
- Brief Report: A Bioassay to Identify Primary Human Prostate Cancer Repopulating Cells
[作者:Toivanen, R; Berman, DM; Wang, H; Pedersen, J; Frydenberg, M; Meeker, AK; Ellem, SJ; Risbridger, GP; Taylor, RA,期刊:Stem Cells, 页码:1310-1314 , 文章类型: Article,,卷期:2011年29-8]
- Cancer cells are heterogeneous in both their phenotypes and ability to promote tumor growth and spread. X-enografting is used to identify the most highly capable cells of regenerating tumors, referred to as cancer repopu...
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