- Concise Review: Stem Cell Effects in Radiation Risk
[作者:Prise, KM; Saran, A,期刊:Stem Cells, 页码:1315-1321 , 文章类型: Review,,卷期:2011年29-9]
- Stem cells of normal mammalian tissues are defined as nonspecialized cells that have two critical properties: (a) the ability to renew themselves through cell division and (b) the potency to differentiate into other cell...
- FoxO3a Functions as a Key Integrator of Cellular Signals That Control Glioblastoma Stem-like Cell Differentiation and Tumorigenicity
[作者:Sunayama, J; Sato, A; Matsuda, KI; Tachibana, K; Watanabe, E; Seino, S; Suzuki, K; Narita, Y; Shibui, S; Sakurada, K; Kayama, T; Tomiyama, A; Kitanaka, C,期刊:Stem Cells, 页码:1327-1337 , 文章类型: Article,,卷期:2011年29-9]
- Glioblastoma is one of the most aggressive types of human cancer, with invariable and fatal recurrence even after multimodal intervention, for which cancer stem-like cells (CSLCs) are now being held responsible. Our rece...
- Human Induced Pluripotent Stem Cells Harbor Homoplasmic and Heteroplasmic Mitochondrial DNA Mutations While Maintaining Human Embryonic Stem Cell-like Metabolic Reprogramming
[作者:Prigione, A; Lichtner, B; Kuhl, H; Struys, EA; Wamelink, M; Lehrach, H; Ralser, M; Timmermann, B; Adjaye, J,期刊:Stem Cells, 页码:1338-1348 , 文章类型: Article,,卷期:2011年29-9]
- Human induced pluripotent stem cells (iPSCs) have been recently found to harbor genomic alterations. However, the integrity of mitochondrial DNA (mtDNA) within reprogrammed cells has yet to be investigated. mtDNA mutatio...
- Radical Acceleration of Nuclear Reprogramming by Chromatin Remodeling with the Transactivation Domain of MyoD
[作者:Hirai, H; Tani, T; Katoku-Kikyo, N; Kellner, S; Karian, P; Firpo, M; Kikyo, N,期刊:Stem Cells, 页码:1349-1361 , 文章类型: Article,,卷期:2011年29-9]
- Induced pluripotent stem cells (iPSCs) can be created by reprogramming differentiated cells through introduction of defined genes, most commonly Oct4, Sox2, Klf4, and c-Myc (OSKM). However, this process is slow and extre...
- The Mitochondrial Electron Transport Chain Is Dispensable for Proliferation and Differentiation of Epidermal Progenitor Cells
[作者:Baris, OR; Klose, A; Kloepper, JE; Weiland, D; Neuhaus, JFG; Schauen, M; Wille, A; Muller, A; Merkwirth, C; Langer, T; Larsson, NG; Krieg, T; Tobin, DJ; Paus, R; Wiesner, RJ,期刊:Stem Cells, 页码:1459-1468 , 文章类型: Article,,卷期:2011年29-9]
- Tissue stem cells and germ line or embryonic stem cells were shown to have reduced oxidative metabolism, which was proposed to be an adaptive mechanism to reduce damage accumulation caused by reactive oxygen species. How...
- Brief Report: Benchmarking Human Pluripotent Stem Cell Markers During Differentiation Into the Three Germ Layers Unveils a Striking Heterogeneity: All Markers Are Not Equal
[作者:Ramirez, JM; Gerbal-Chaloin, S; Milhavet, O; Qiang, B; Becker, F; Assou, S; Lemaitre, JM; Hamamah, S; De Vos, J,期刊:Stem Cells, 页码:1469-1474 , 文章类型: Article,,卷期:2011年29-9]
- Pluripotent stem cells (PSC) are functionally characterized by their capacity to differentiate into all the cell types from the three germ layers. A wide range of markers, the expression of which is associated with pluri...
- Crucial Role of C-Myc in the Generation of Induced Pluripotent Stem Cells
[作者:Araki, R; Hoki, Y; Uda, M; Nakamura, M; Jincho, Y; Tamura, C; Sunayama, M; Ando, S; Sugiura, M; Yoshida, MA; Kasama, Y; Abe, M,期刊:Stem Cells, 页码:1362-1370 , 文章类型: Article,,卷期:2011年29-9]
- c-Myc transduction has been considered previously to be nonessential for induced pluripotent stem cell (iPSC) generation. In this study, we investigated the effects of c-Myc transduction on the generation of iPSCs from a...
- Pax7 Expressing Cells Contribute to Dermal Wound Repair, Regulating Scar Size through a beta-Catenin Mediated Process
[作者:Amini-Nik, S; Glancy, D; Boimer, C; Whetstone, H; Keller, C; Alman, BA,期刊:Stem Cells, 页码:1371-1379 , 文章类型: Article,,卷期:2011年29-9]
- During skin wound healing, fibroblast-like cells reconstitute the dermal compartment of the repaired skin filling the wound gap. A subset of these cells are transcriptionally active for beta-catenin/T-cell factor (TCF) s...
- Repair of Critical-Sized Rat Calvarial Defects Using Genetically Engineered Bone Marrow-Derived Mesenchymal Stem Cells Overexpressing Hypoxia-Inducible Factor-1 alpha
[作者:Zou, DH; Zhang, ZY; Ye, DX; Tang, AF; Deng, LF; Han, W; Zhao, J; Wang, SH; Zhang, WJ; Zhu, C; Zhou, J; He, JC; Wang, YY; Xu, F; Huang, YL; Jiang, XQ,期刊:Stem Cells, 页码:1380-1390 , 文章类型: Article,,卷期:2011年29-9]
- The processes of angiogenesis and bone formation are coupled both temporally and spatially during bone repair. Bone marrow-derived mesenchymal stem cells (BMSCs) have been effectively used to heal critical-size bone defe...
- Effective Transplantation of Photoreceptor Precursor Cells Selected Via Cell Surface Antigen Expression
[作者:Lakowski, J; Han, YT; Pearson, RA; Gonzalez-Cordero, A; West, EL; Gualdoni, S; Barber, AC; Hubank, M; Ali, RR; Sowden, JC,期刊:Stem Cells, 页码:1391-1404 , 文章类型: Article,,卷期:2011年29-9]
- Retinal degenerative diseases are a major cause of untreatable blindness. Stem cell therapy to replace lost photoreceptors represents a feasible future treatment. We previously demonstrated that postmitotic photoreceptor...
- Treatment of Human Mesenchymal Stem Cells with Angiotensin Receptor Blocker Improved Efficiency of Cardiomyogenic Transdifferentiation and Improved Cardiac Function via Angiogenesis
[作者:Numasawa, Y; Kimura, T; Miyoshi, S; Nishiyama, N; Hida, N; Tsuji, H; Tsuruta, H; Segawa, K; Ogawa, S; Umezawa, A,期刊:Stem Cells, 页码:1405-1414 , 文章类型: Article,,卷期:2011年29-9]
- To improve the modest efficacy of mesenchymal stem cell (MSC) transplantation, the treatment of human MSCs with angiotensin receptor blockers (ARBs) was investigated. MSCs were cultured with or without the medium contain...
- Expression of Tlx in Both Stem Cells and Transit Amplifying Progenitors Regulates Stem Cell Activation and Differentiation in the Neonatal Lateral Subependymal Zone
[作者:Obernier, K; Simeonova, I; Fila, T; Mandl, C; Holzl-Wenig, G; Monaghan-Nichols, P; Ciccolini, F,期刊:Stem Cells, 页码:1415-1426 , 文章类型: Article,,卷期:2011年29-9]
- Niche homeostasis in the postnatal subependymal zone of the lateral ventricle (lSEZ) requires coordinated proliferation and differentiation of neural progenitor cells. The mechanisms regulating this balance are scarcely ...
- Establishment of Human Trophoblast Progenitor Cell Lines from the Chorion
[作者:Genbacev, O; Donne, M; Kapidzic, M; Gormley, M; Lamb, J; Gilmore, J; Larocque, N; Goldfien, G; Zdravkovic, T; McMaster, MT; Fisher, SJ,期刊:Stem Cells, 页码:1427-1436 , 文章类型: Article,,卷期:2011年29-9]
- Placental trophoblasts are key determinants of in utero development. Mouse trophoblast (TB) stem cells, which were first derived over a decade ago, are a powerful cell culture model for studying their self-renewal or dif...
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