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  • Free [NADH]/[NAD(+)] regulates sirtuin expression
    [作者:Gambini, J; Gomez-Cabrera, MC; Borras, C; Valles, SL; Lopez-Grueso, R; Martinez-Bello, VE; Herranz, D; Pallardo, FV; Tresguerres, JAF; Serrano, M; Vina, J,期刊:Archives of Biochemistry and Biophysics , 页码:24-29 , 文章类型: Article,,卷期:2011年512-1]
  • Sirtuins are deacetylases involved in metabolic regulation and longevity. Our aim was to test the hypothesis that they are subjected to redox regulation by the [NADH]/[NAD(+)] ratio. We used NIH3T3 fibroblasts in culture...