- Myosin II regulates extension, growth and patterning in the mammalian cochlear duct
[作者:Yamamoto, N; Okano, T; Ma, XF; Adelstein, RS; Kelley, MW,期刊:Development, 页码:1977-1986 , 文章类型: Article,,卷期:2009年136-12]
- The sensory epithelium of the mammalian cochlea comprises mechanosensory hair cells that are arranged into four ordered rows extending along the length of the cochlear spiral. The factors that regulate the alignment of t...
- Genetic ablation of neural crest cell diversification
[作者:Arduini, BL; Bosse, KM; Henion, PD,期刊:Development, 页码:1987-1994 , 文章类型: Article,,卷期:2009年136-12]
- The neural crest generates multiple cell types during embryogenesis but the mechanisms regulating neural crest cell diversification are incompletely understood. Previous studies using mutant zebrafish indicated that foxd...
- Evolutionary origins of blastoporal expression and organizer activity of the vertebrate gastrula organizer gene lhx1 and its ancient metazoan paralog lhx3
[作者:Yasuoka, Y; Kobayashi, M; Kurokawa, D; Akasaka, K; Saiga, H; Taira, M,期刊:Development, 页码:2005-2014 , 文章类型: Article,,卷期:2009年136-12]
- Expression of the LIM homeobox gene lhx1 (lim1) is specific to the vertebrate gastrula organizer. Lhx1 functions as a transcriptional regulatory core protein to exert 'organizer' activity in Xenopus embryos. Its ancient ...
- Juvenile hormone counteracts the bHLH-PAS transcription factors MET and GCE to prevent caspase-dependent programmed cell death in Drosophila
[作者:Liu, Y; Sheng, ZT; Liu, HH; Wen, D; He, QY; Wang, S; Shao, W; Jiang, RJ; An, SH; Sun, YN; Bendena, WG; Wang, J; Gilbert, LI; Wilson, TG; Song, QS; Li, S,期刊:Development, 页码:2015-2025 , 文章类型: Article,,卷期:2009年136-12]
- Juvenile hormone (JH) regulates many developmental and physiological events in insects, but its molecular mechanism remains conjectural. Here we report that genetic ablation of the corpus allatum cells of the Drosophila ...
- PTK7 is essential for polarized cell motility and convergent extension during mouse gastrulation
[作者:Yen, WW; Williams, M; Periasamy, A; Conaway, M; Burdsal, C; Keller, R; Lu, XW; Sutherland, A,期刊:Development, 页码:2039-2048 , 文章类型: Article,,卷期:2009年136-12]
- Despite being implicated as a mechanism driving gastrulation and body axis elongation in mouse embryos, the cellular mechanisms underlying mammalian convergent extension (CE) are unknown. Here we show, with high-resoluti...
- Inhibitory and excitatory subtypes of cochlear nucleus neurons are defined by distinct bHLH transcription factors, Ptf1a and Atoh1
[作者:Fujiyama, T; Yamada, M; Terao, M; Terashima, T; Hioki, H; Inoue, YU; Inoue, T; Masuyama, N; Obata, K; Yanagawa, Y; Kawaguchi, Y; Nabeshima, Y; Hoshino, M,期刊:Development, 页码:2049-2058 , 文章类型: Article,,卷期:2009年136-12]
- The cochlear nucleus (CN), which consists of dorsal and ventral cochlear nuclei (DCN and VCN), plays pivotal roles in processing and relaying auditory information to the brain. Although it contains various types of neuro...
- Dynamic, auxin-responsive plasma membrane-to-nucleus movement of Arabidopsis BRX
[作者:Scacchi, E; Osmont, KS; Beuchat, J; Salinas, P; Navarrete-Gomez, M; Trigueros, M; Ferrandiz, C; Hardtke, CS,期刊:Development, 页码:2059-2067 , 文章类型: Article,,卷期:2009年136-12]
- In Arabidopsis, interplay between nuclear auxin perception and trans-cellular polar auxin transport determines the transcriptional auxin response. In brevis radix (brx) mutants, this response is impaired, probably indire...
- The novel protein kinase Vlk is essential for stromal function of mesenchymal cells
[作者:Kinoshita, M; Era, T; Jakt, LM; Nishikawa, SI,期刊:Development, 页码:2069-2079 , 文章类型: Article,,卷期:2009年136-12]
- From a list of protein kinases (PKs) that are newly induced upon differentiation of mouse embryonic stem cells to mesendoderm, we identified a previously uncharacterized kinase, Vlk (vertebrate lonesome kinase), that is ...
- Expression of the Arf tumor suppressor gene is controlled by Tgf beta 2 during development
[作者:Freeman-Anderson, NE; Zheng, YB; McCalla-Martin, AC; Treanor, LM; Zhao, YD; Garfin, PM; He, TC; Mary, MN; Thornton, JD; Anderson, C; Gibbons, M; Saab, R; Baumer, SH; Cunningham, JM; Skapek, SX,期刊:Development, 页码:2081-2089 , 文章类型: Article,,卷期:2009年136-12]
- The Arf tumor suppressor ( also known as Cdkn2a) acts as an oncogene sensor induced by 'abnormal' mitogenic signals in incipient cancer cells. It also plays a crucial role in embryonic development: newborn mice lacking A...
- Down syndrome critical region protein 5 regulates membrane localization of Wnt receptors, Dishevelled stability and convergent extension in vertebrate embryos
[作者:Shao, M; Liu, ZZ; Wang, CD; Li, HY; Carron, C; Zhang, HW; Shi, DL,期刊:Development, 页码:2121-2131 , 文章类型: Article,,卷期:2009年136-12]
- The Glypican family of heparan sulfate proteoglycans regulates Wnt signaling and convergent extension (CE) in vertebrate embryos. They are predicted to be glycosylphosphatidylinositol (GPI)-tethered membrane-bound protei...
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