- Carcinogenesis, prevention and early detection of gastric cancer: Where we are and where we should go
[作者：Gonzalez, CA; Agudo, A,期刊：International Journal of Cancer, 页码：745-753 , 文章类型： Review，,卷期：2012年130-4]
- Helicobacter pylori is the most common cause of gastric cancer (GC), though smoking, alcohol, diet, genetics and epigenetic factors may also have a role in the occurrence of the disease. Why H. pylori cause GC in only a ...
- Impact of intracellular alpha fetoprotein on retinoic acid receptors-mediated expression of GADD153 in human hepatoma cell lines
[作者：Li, CY; Wang, SS; Jiang, W; Li, H; Liu, ZM; Zhang, C; McNutt, MA; Li, G,期刊：International Journal of Cancer, 页码：754-764 , 文章类型： Article，,卷期：2012年130-4]
- The aim of our study was to gain a better understanding of the molecular mechanism underlying the previously unrecognized role of cytoplasmic alpha fetoprotein (AFP) in retinoic acid receptors (RAR) mediated expression a...
- Cell mediated immune responses through TLR4 prevents DMBA-induced mammary carcinogenesis in mice
[作者：Naseemuddin, M; Iqbal, A; Nasti, TH; Ghandhi, JL; Kapadia, AD; Yusuf, N,期刊：International Journal of Cancer, 页码：765-774 , 文章类型： Article，,卷期：2012年130-4]
- Toll-like receptors (TLRs) activate signals that are critically involved in the initiation of adaptive immune responses and many tumorigenic chemicals have been associated with activation of those pathways. To determine ...
- The impact of amyloid precursor protein signalling and histone deacetylase inhibition on neprilysin expression in human prostate cells
[作者：Hong, Y; Beckett, C; Belyaev, ND; Turner, AJ,期刊：International Journal of Cancer, 页码：775-786 , 文章类型： Article，,卷期：2012年130-4]
- The zinc metallopeptidase, neprilysin (NEP), is an endothelin-1 degrading enzyme whose expression is extensively downregulated in prostate cancer. The expression of NEP in neuronal cells is regulated by intramembrane pro...
- Lymphatic endothelial cell-secreted CXCL1 stimulates lymphangiogenesis and metastasis of gastric cancer
[作者：Xu, JB; Zhang, CH; He, YL; Wu, H; Wang, Z; Song, W; Li, W; He, WL; Cai, SR; Zhan, WH,期刊：International Journal of Cancer, 页码：787-797 , 文章类型： Article，,卷期：2012年130-4]
- Lymph node metastasis is a significant factor in gastric cancer prognosis. It is well known that cancer cells secrete lymphangiogenic factors, thereby promoting lymphangiogenesis. However, the effects of lymphatic endoth...
- Expression of epithelial-mesenchymal transition-inducing transcription factors in primary breast cancer: The effect of neoadjuvant therapy
[作者：Mego, M; Mani, SA; Lee, BN; Li, CP; Evans, KW; Cohen, EN; Gao, H; Jackson, SA; Giordano, A; Hortobagyi, GN; Cristofanilli, M; Lucci, A; Reuben, JM,期刊：International Journal of Cancer, 页码：808-816 , 文章类型： Article，,卷期：2012年130-4]
- Epithelial cancer cells are likely to undergo epithelialmesenchymal transition (EMT) prior to entering the peripheral circulation. By undergoing EMT, circulating tumor cells (CTCs) lose epithelial markers and may escape ...
- Brain-derived neurotrophic factor is a potential osteoclast stimulating factor in multiple myeloma
[作者：Sun, CY; Chu, ZB; She, XM; Zhang, L; Chen, L; Ai, LS; Hu, Y,期刊：International Journal of Cancer, 页码：827-836 , 文章类型： Article，,卷期：2012年130-4]
- Multiple myeloma (MM) is characterized by accumulation of monoclonal plasma cells in the bone marrow and progression of lytic bone lesions. The mechanisms of enhanced bone resorption in patients with myeloma are not full...
- Increased frequency of 20q gain and copy-neutral loss of heterozygosity in mismatch repair proficient familial colorectal carcinomas
[作者：Middeldorp, A; van Eijk, R; Oosting, J; Forte, GI; van Puijenbroek, M; van Nieuwenhuizen, M; Corver, WE; Ruano, D; Caldes, T; Wijnen, J; Morreau, H; van Wezel, T,期刊：International Journal of Cancer, 页码：837-846 , 文章类型： Article，,卷期：2012年130-4]
- Many hereditary nonpolyposis colorectal cancers (CRCs) cannot be explained by Lynch syndrome. Other high penetrance genetic risk factors are likely to play a role in these mismatch repair (MMR)-proficient CRC families. B...
- An intact retinoblastoma protein-binding site in Merkel cell polyomavirus large T antigen is required for promoting growth of Merkel cell carcinoma cells
[作者：Houben, R; Adam, C; Baeurle, A; Hesbacher, S; Grimm, J; Angermeyer, S; Henzel, K; Hauser, S; Elling, R; Brocker, EB; Gaubatz, S; Becker, JC; Schrama, D,期刊：International Journal of Cancer, 页码：847-856 , 文章类型： Article，,卷期：2012年130-4]
- Merkel cell carcinoma (MCC) is a highly aggressive skin cancer that frequently harbours Merkel cell polyomavirus (MCV) DNA integrated in the genome of the tumor cells. In our study, we elaborate our recent finding that M...
- VEGF directly suppresses activation of T cells from ovarian cancer patients and healthy individuals via VEGF receptor Type 2
[作者：Ziogas, AC; Gavalas, NG; Tsiatas, M; Tsitsilonis, O; Politi, E; Terpos, E; Rodolakis, A; Vlahos, G; Thomakos, N; Haidopoulos, D; Antsaklis, A; Dimopoulos, MA; Bamias, A,期刊：International Journal of Cancer, 页码：857-864 , 文章类型： Article，,卷期：2012年130-4]
- The role of vascular endothelial growth factor (VEGF) in tumor angiogenesis is well characterized; nevertheless, it is also a key element in promoting tumor evasion of the immune system by downregulating dendritic cell m...
- Immunotherapeutic efficacy of Mycobacterium indicus pranii in eliciting anti-tumor T cell responses: Critical roles of IFN gamma
[作者：Rakshit, S; Ponnusamy, M; Papanna, S; Saha, B; Ahmed, A; Nandi, D,期刊：International Journal of Cancer, 页码：865-875 , 文章类型： Article，,卷期：2012年130-4]
- Mycobacterium indicus pranii (MIP) is approved for use as an adjuvant (Immuvac/Cadi-05) in the treatment of leprosy. In addition, its efficacy is being investigated in clinical trials on patients with tuberculosis and di...
- Significant associations of prostate cancer susceptibility variants with survival in patients treated with androgen-deprivation therapy
[作者：Bao, BY; Pao, JB; Huang, CN; Pu, YS; Chang, TY; Lan, YH; Lu, TL; Lee, HZ; Chen, LM; Ting, WC; Hsieh, CJ; Huang, SP,期刊：International Journal of Cancer, 页码：876-884 , 文章类型： Article，,卷期：2012年130-4]
- Androgen-deprivation therapy (ADT) is the most common therapy for advanced prostate cancer, but the prognosis significantly differs among individuals. In this study, we evaluated recently identified 19 prostate cancer su...
- Downregulation of zinc finger protein 132 in prostate cancer is associated with aberrant promoter hypermethylation and poor prognosis
[作者：Abildgaard, MO; Borre, M; Mortensen, MM; Ulhoi, BP; Torring, N; Wild, P; Kristensen, H; Mansilla, F; Ottosen, PD; Dyrskjot, L; Orntoft, TF; Sorensen, KD,期刊：International Journal of Cancer, 页码：885-895 , 文章类型： Article，,卷期：2012年130-4]
- This study investigates the expression and biomarker potential of zinc finger protein 132 (ZNF132) in prostate cancer (PC) by transcriptional profiling and immunohistochemical analysis of tissue microarrays, including tu...
- Cigarette smoking and subtypes of bladder cancer
[作者：Jiang, XJ; Castelao, JE; Yuan, JM; Stern, MC; Conti, DV; Cortessis, VK; Pike, MC; Gago-Dominguez, M,期刊：International Journal of Cancer, 页码：896-901 , 文章类型： Article，,卷期：2012年130-4]
- There is little information regarding associations between suspected bladder cancer risk factors and tumor subtypes at diagnosis. Some, but not all, studies have found that bladder cancer among smokers is often more inva...
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