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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共6条记录   VORAPAXAR PAR1 Receptor Antagonist Antiplatelet Therapy [作者：Goto, S; Serebruany, V,期刊：Drugs of the Future, 页码：101-113 , 文章类型： Article，,卷期：2011年36-2] Atherothrombosis, including myocardial infarction and ischemic stroke, is a highly prevalent disease throughout the world. Platelet activation plays a crucial role in the onset of atherothrombotic events, while detailed ... PERSPECTIVES IN THE TREATMENT OF PRURITUS: FOCUS ON NEW STRATEGIES [作者：Tey, HL; Yosipovitch, G,期刊：Drugs of the Future, 页码：115-121 , 文章类型： Review，,卷期：2011年36-2] Pruritus is a common symptom and the main source of morbidity in dermatologic diseases. Current management has been hampered by our inadequate understanding of the pathomechanisms of pruritus, but recent advances in eluc... THE ROLE OF NEUROTROPHINS AND MIMETICS IN THE TREATMENT OF OCULAR DISEASES [作者：Bai, Y; Ge, J; Saragovi, HU; Zhuo, Y,期刊：Drugs of the Future, 页码：123-131 , 文章类型： Review，,卷期：2011年36-2] The optic nerve is a bundle of fibers and axons projecting from specialized retinal neurons, the retinal ganglion cells (RGCs), which make synaptic connections to the visual cortex. Glaucoma is a chronic and progressive ... TARGETING EARLY EVENTS IN CYSTIC FIBROSIS DISEASE PATHOGENESIS [作者：Hoover, W; Clancy, JP,期刊：Drugs of the Future, 页码：133-140 , 文章类型： Article，,卷期：2011年36-2] Cystic fibrosis (CF) is a chronic and debilitating genetic disease that occurs in over 70,000 people worldwide. Advances in treatment have led to significant improvements in longevity since the disorder was first describ... ACIDIC MAMMALIAN CHITINASE (AMCASE): A NEW TARGET FOR OCULAR DISEASES [作者：Musumeci, M; Bucolo, C; Drago, F; Musumeci, S,期刊：Drugs of the Future, 页码：141-148 , 文章类型： Article，,卷期：2011年36-2] Chitin, the second most abundant polysaccharide in nature, is not expressed in mammalian systems, but is found in the structural coatings of fungi, the exoskeleton of many arthropods and parasitic nematodes. The host def... CRIZOTINIB ALK/Met inhibitor Oncolytic [作者：Nwizu, T; Kanteti, R; Kawada, I; Rolle, C; Vokes, EE; Salgia, R,期刊：Drugs of the Future, 页码：91-99 , 文章类型： Article，,卷期：2011年36-2] There are a number of molecular abnormalities that can occur in normal cells to induce a malignant phenotype. Recently, the tyrosine kinase receptor anaplastic lymphoma kinase (ALK) has been shown to have gain of functio...