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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共6条记录   BRIAKINUMAB Human Anti-IL-12/23 Monoclonal Antibody Treatment of Psoriasis Treatment of Crohn's disease [作者：Crowley, JJ,期刊：Drugs of the Future, 页码：267-271 , 文章类型： Article，,卷期：2011年36-4] Briakinumab (ABT-874) is a fully human monoclonal antibody targeting the p40 subunit of both interleukin-72 (IL-12) and -23 (IL-23). It is currently being studied in psoriasis and Crohn's disease. Psoriasis is an inflamm... FOSTAMATINIB DISODIUM Tyrosine-Protein Kinase SYK/FLT3 Inhibitor Treatment of Rheumatoid Arthritis Oncolytic [作者：McAdoo, SP; Tam, FWK,期刊：Drugs of the Future, 页码：273-280 , 文章类型： Article，,卷期：2011年36-4] The non-receptor tyrosine-protein kinase SYK (spleen tyrosine kinase) has a diverse range of biological functions, including a critical role in the intracellular signaling cascade for the surface immunoglobulin receptor ... NGR-hTNF Vascular Targeting Agent Oncolytic [作者：Vasitiou, S; Suria, R,期刊：Drugs of the Future, 页码：281-285 , 文章类型： Article，,卷期：2011年36-4] NGR-hTNF is a vascular targeting agent that consists of a modified form of human TNF-alpha fused with an NGR peptide. The NGR peptide moiety of the compound acts by selectively targeting blood vessels, where TNF is relea... NOVEL THERAPEUTIC APPROACHES FOR GLAUCOMA [作者：Rasmussen, CA; Kaufman, PL,期刊：Drugs of the Future, 页码：287-300 , 文章类型： Review，,卷期：2011年36-4] Glaucoma refers to a collection of progressive optic neuropathies that can lead to irreversible damage to retinal ganglion cells and their axons, and eventual loss of vision if left untreated or treated unsuccessfully. T... THE THERAPEUTIC POTENTIAL OF BRADYKININ B(1) RECEPTOR ANTAGONISTS IN CHRONIC PAIN [作者：Farkas, S; Eles, J,期刊：Drugs of the Future, 页码：301-319 , 文章类型： Review，,卷期：2011年36-4] After the rise and fall of cyclooxygenase-2 (COX-2)-selective inhibitors as safe replacements for nonsteroidal antiinflammatory drugs (NSAIDs), particularly for the treatment of chronic painful conditions in the elderly,... EXPLORING THE ROLE OF PHOSPHODIESTERASE PDE5 INHIBITION IN THE TREATMENT OF MUSCULAR DYSTROPHY [作者：Yasuhara, SE,期刊：Drugs of the Future, 页码：321-339 , 文章类型： Article，,卷期：2011年36-4] Duchenne muscular dystrophy (DMD) is caused by a mutation of a single gene, dystrophin, and is characterized by a slow progression and the increased turnover of myofiber degeneration and regeneration. Despite the long hi...