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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共7条记录   GEMCITABINE ELAIDATE Cytotoxic Agent Oncolytic [作者：Venugopal, B; Evans, TRJ,期刊：Drugs of the Future, 页码：427-432 , 文章类型： Article，,卷期：2011年36-6] Cemcitabine is an established chemotherapeutic agent for the treatment of a variety of malignancies, including pancreatic, bladder, breast and non-small cell lung cancers. Cemcitabine requires specialized nucleoside tran... ON 01910.Na Polo-Like Kinase Inhibitor Oncolytic [作者：Taft, DR; Dave, R; Gillum, AM; Maniar, M,期刊：Drugs of the Future, 页码：433-440 , 文章类型： Article，,卷期：2011年36-6] ON 07970.Na (rigosertib, Estybon (R)) is a novel small molecule developed to treat cancer. It has a multitargeted mechanism of action, including polo-like kinase inhibition, resulting in selective blockade of mitosis and... SECUKINUMAB Fully Human Anti-IL-17 Monoclonal Antibody [作者：Gonzalez-Gonzalez, LA; Foster, CS,期刊：Drugs of the Future, 页码：441-445 , 文章类型： Article，,卷期：2011年36-6] Secukinumab (AIN-457) is a fully human monoclonal antibody that neutralizes IL-17, thus affecting the immune response driven by Th17 lymphocytes. The Th17 response has been described to contribute to the inflammatory rea... VELUSETRAG 5-HT(4) Receptor Agonist Treatment of Chronic Constipation [作者：Vazquez-Roque, M; Camilleri, M,期刊：Drugs of the Future, 页码：447-454 , 文章类型： Article，,卷期：2011年36-6] Chronic constipation and irritable bowel syndrome (IBS) with constipation affect patient quality of life and are associated with a high healthcare expenditure. Conventional therapies for chronic constipation have limited... ANTIVIRAL DRUG SUSCEPTIBILITY PATTERNS IN GAMMARETROVIRIDAE: LESSONS FROM XMRV AND RELATED RETROVIRUSES [作者：Smith, RA,期刊：Drugs of the Future, 页码：455-463 , 文章类型： Review，,卷期：2011年36-6] Gammaretroviruses include several well-characterized, exogenous mammalian retroviruses that cause cancer and other diseases following infection of susceptible hosts. Recent reports of a newly discovered gammaretrovirus, ... CHEMOKINE RECEPTOR CXCR2 ANTAGONISM TO PREVENT AIRWAYS INFLAMMATION [作者：Donnelly, LE; Barnes, PJ,期刊：Drugs of the Future, 页码：465-472 , 文章类型： Review，,卷期：2011年36-6] Neutrophilic inflammation is associated with several pulmonary conditions, including chronic obstructive pulmonary disease (CORD), severe asthma and cystic fibrosis, and contributes to disease pathophysiology. The underl... THERAPEUTIC TARGETS FOR ANXIETY DISORDERS [作者：Sorbera, LA; Dulsat, C; Rosa, E,期刊：Drugs of the Future, 页码：473-484 , 文章类型： Article，,卷期：2011年36-6] Anxiety disorders are a group of psychiatric illnesses characterized by extreme or pathological anxiety, resulting in alterations in mood or emotional tone. They are the most frequent of all mental disorders encountered ...