个性化文献订阅>文章检索

文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共7条记录   NVC-422 Antiinfective Agent Treatment of Impetigo Treatment of Conjunctivitis Treatment of Urinary Tract Infections [作者：Darouiche, R; Najafi, R; Krantz, K; Debabov, D; Friedman, L; Khosrovi, B; Wang, L; Iovine, S; Anderson, M,期刊：Drugs of the Future, 页码：651-656 , 文章类型： Article，,卷期：2011年36-9] NVC-422 is a first-in-class synthetic stable chlorotaurine exhibiting a broad spectrum of activity against Gram-positive and Gram-negative pathogens, without the potential for developing drug resistance. Nova Bay has nam... OBINUTUZUMAB Humanized Anti-CD20 Monoclonal Antibody Apoptosis Inducer Oncolytic [作者：Karlin, L; Salles, G,期刊：Drugs of the Future, 页码：657-662 , 文章类型： Article，,卷期：2011年36-9] The emergence of anti-CD20 monoclonal antibodies (MAbs), especially rituximab, has dramatically improved the treatment of B-cell malignancies during the past 10 years. However, many patients still experience refractory f... TH-302 DNA Alkylating Agent Hypoxia-Activated Cytotoxic Prodrug Oncolytic [作者：Pento, JT,期刊：Drugs of the Future, 页码：663-667 , 文章类型： Article，,卷期：2011年36-9] Since cancer cells do not produce blood vessels, tumors usually contain regions of hypoxia with relatively low metabolic activity and regions with relatively normal oxygenation where cancer cells grow much more rapidly. ... IRRITABLE BOWEL SYNDROME - PRINCIPLES AND NOVEL TREATMENT OPTIONS [作者：Hellstrom, PM; Webb, DL,期刊：Drugs of the Future, 页码：669-675 , 文章类型： Review，,卷期：2011年36-9] There is growing interest in the area of irritable bowel syndrome (IBS) in developing tools to separate various subgroups of this disease in order to identify potentially different pathogenetic mechanisms. From such work... gamma-SECRETASE INHIBITORS IN SOLID TUMOR MALIGNANCIES [作者：Arcaroli, JJ; Dasari, A; Messersmith, WA; Jimeno, A,期刊：Drugs of the Future, 页码：677-689 , 文章类型： Review，,卷期：2011年36-9] The Notch pathway, like other developmental pathways such as hedgehog and Wnt, has diverse pleiotropic functions. The Notch pathway has a well-recognized role in hematological malignancies and recent research has also es... TARGETING THE NS5A PROTEIN OF HCV: AN EMERGING OPTION [作者：Cordek, DC; Bechtel, JT; Maynard, AT; Kazmierski, WM; Cameron, CE,期刊：Drugs of the Future, 页码：691-711 , 文章类型： Article，,卷期：2011年36-9] Hepatitis C virus (HCV) infects more than 3% of the world's population, leading to an increased risk of cirrhosis and hepatocellular carcinoma. The current standard of care, a combination of pegylated interferon alfa and... CARBOXYETHYLPYRROLE PLASMA BIOMARKERS IN AGE-RELATED MACULAR DEGENERATION [作者：Ardeljan, D; Tuo, J; Chan, CC,期刊：Drugs of the Future, 页码：713-718 , 文章类型： Article，,卷期：2011年36-9] Age-related macular degeneration causes irreversible central blindness in people over the age of 50 and is increasing in prevalence among elderly populations. There are currently limited treatment options available for t...