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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共8条记录   Untitled [作者：Prous, J,期刊：Drugs of the Future, 页码：3-3 , 文章类型： Editorial Material，,卷期：2011年36-1] ENMD-2076 Aurora Kinase A Inhibitor Protein Kinase Inhibitor Oncolytic [作者：Zhang, S; Farag, SS,期刊：Drugs of the Future, 页码：5-15 , 文章类型： Article，,卷期：2011年36-1] ENMD-2076 is a novel, orally active molecule that has been shown to have significant activity against Aurora kinases and multiple tyrosine-protein kinases, including tyrosine-protein kinase receptor FLT3, protooncogene c... REGORAFENIB Broad-Spectrum Kinase Inhibitor Oncolytic [作者：Marrari, A; George, S,期刊：Drugs of the Future, 页码：17-23 , 文章类型： Article，,卷期：2011年36-1] Regorafenib is an orally active inhibitor of VEGFR-2 and -3, c-Kit, TIE-2, PDGF-R-beta, FGFR-7, Ret, c-RAF and MAP kinase p38. Preclinical in vitro and in vivo studies demonstrate a broad spectrum of activity, likely due... CONOPEPTIDES AS NOVEL OPTIONS FOR PAIN MANAGEMENT [作者：Daly, NL; Craik, DJ,期刊：Drugs of the Future, 页码：25-32 , 文章类型： Review，,卷期：2011年36-1] Conopeptides are the peptidic components of the venoms of marine cone snails from the Conus genus. Aside from their natural function in pharmacologically immobilizing prey, they have attracted the attention of drug desig... VASOPEPTIDASE INHIBITION - SOLVING THE CARDIOVASCULAR PUZZLE? [作者：Douglas, RG; Ehlers, MRW; Sturrock, ED,期刊：Drugs of the Future, 页码：33-43 , 文章类型： Review，,卷期：2011年36-1] The therapeutic blockade of the renin-angiotensin-aldosterone system (RAAS) using angiotensin-converting enzyme (ACE) inhibitors, angiotensin,receptor blockers, aldosterone receptor antagonists and, more recently, renin ... DENGUE VACCINES: NEW DEVELOPMENTS [作者：Guzman, MG,期刊：Drugs of the Future, 页码：45-62 , 文章类型： Article，,卷期：2011年36-1] Dengue represents a major, growing public health problem, with an estimated of 2.5 billion people at risk of infection and about 50 million cases. Vector control is the only way of controlling dengue transmission; howeve... RAF KINASE INHIBITORS FOR THE TREATMENT OF MELANOMA [作者：Nimmagadda, N; Tawbi, H,期刊：Drugs of the Future, 页码：63-68 , 文章类型： Article，,卷期：2011年36-1] Malignant melanoma is one of the most lethal solid tumors unless detected early. Malignant melanoma accounts for about 75% of skin cancer-related deaths. Around 68,700 cases of new melanoma were diagnosed in 2009 in the ... MOLECULAR IMAGING WITH SPECT AND PET IN EXPLORATORY INVESTIGATIONAL NEW DRUG STUDIES [作者：Gomes, CMF; Abrunhosa, AJ; Pauwels, EKJ,期刊：Drugs of the Future, 页码：69-77 , 文章类型： Article，,卷期：2011年36-1] The phase O microdosing concept was introduced recently by the FDA in order to shorten the timeline for drug development and to reduce the overall cost of the process. The aim of this approach is to provide drug pharmaco...