- Randomized, Double-Blind Controlled Phase 3 Trial Comparing the Immunogenicity of High-Dose and Standard-Dose Influenza Vaccine in Adults 65 Years of Age and Older
[作者:Falsey, AR; Treanor, JJ; Tornieporth, N; Capellan, J; Gorse, GJ,期刊:Journal of Infectious Diseases, 页码:172-180 , 文章类型: Article,,卷期:2009年200-2]
- Background. Influenza-associated morbidity and mortality has not decreased in the last decade, despite increased receipt of vaccine. To improve the immunogenicity of influenza vaccine, a high-dose (HD) trivalent, inactiv...
- DNA Vaccination with a Single-Plasmid Construct Coding for Viruslike Particles Protects Mice against Infection with a Highly Pathogenic Avian Influenza A Virus
[作者:Szecsi, J; Gabriel, G; Edfeldt, G; Michelet, M; Klenk, HD; Cosset, FL,期刊:Journal of Infectious Diseases, 页码:181-190 , 文章类型: Article,,卷期:2009年200-2]
- Background. With seasonal outbreaks affecting millions of people each year and devastating pandemics, human influenza is a major health concern. The pandemic threat includes highly pathogenic avian influenza viruses (HPA...
- Impact of Acyclovir on Genital and Plasma HIV-1 RNA, Genital Herpes Simplex Virus Type 2 DNA, and Ulcer Healing among HIV-1-Infected African Women with Herpes Ulcers: A Randomized Placebo-Controlled Trial
[作者:Mayaud, P; LeGoff, J; Weiss, HA; Gresenguet, G; Nzambi, K; Bouhlal, H; Frost, E; Pepin, J; Malkin, JE; Hayes, RJ; Mabey, DCW; Belec, L,期刊:Journal of Infectious Diseases, 页码:216-226 , 文章类型: Article,,卷期:2009年200-2]
- Background. Little is known about the impact of episodic treatment of herpes on human immunodeficiency virus type 1 (HIV-1).Methods. Women from Ghana and the Central African Republic who had genital ulcers were enrolled ...
- Mother-to-Child Transmission of GB Virus C in a Cohort of Women Coinfected with GB Virus C and HIV in Bangkok, Thailand
[作者:Supapol, WB; Remis, RS; Raboud, J; Millson, M; Tappero, J; Kaul, R; Kulkarni, P; McConnell, MS; Mock, PA; McNicholl, JM; Vanprapar, N; Asavapiriyanont, S; Shaffer, N; Butera, S,期刊:Journal of Infectious Diseases, 页码:227-235 , 文章类型: Article,,卷期:2009年200-2]
- Background. GB virus C (GBV-C) is an apathogenic virus that inhibits human immunodeficiency virus (HIV) replication in vitro. Mother-to-child transmission (MTCT) of GBV-C has been observed in multiple small studies. Our ...
- Differential HIV Epitope Processing in Monocytes and CD4 T Cells Affects Cytotoxic T Lymphocyte Recognition
[作者:Lazaro, E; Godfrey, SB; Stamegna, P; Ogbechie, T; Kerrigan, C; Zhang, M; Walker, BD; Le Gall, S,期刊:Journal of Infectious Diseases, 页码:236-243 , 文章类型: Article,,卷期:2009年200-2]
- The ability of cytotoxic T lymphocytes (CTLs) to clear virus-infected cells is dependent on the presentation of viral peptides processed intracellularly and displayed by major histocompatibility complex class I. Most CTL...
- IgM(+) Memory B Cell Expression Predicts HIV-Associated Cryptococcosis Status
[作者:Subramaniam, K; Metzger, B; Hanau, LH; Guh, A; Rucker, L; Badri, S; Pirofski, LA,期刊:Journal of Infectious Diseases, 页码:244-251 , 文章类型: Article,,卷期:2009年200-2]
- Background. The role of B cells in resistance to Cryptococcus neoformans disease (i.e., cryptococcosis) is unknown. Given evidence that IgM(+) memory B cells are required for immunity to other encapsulated pathogens, we ...
- Gene Expression and Immunohistochemistry in Adipose Tissue of HIV Type 1-Infected Patients with Nucleoside Analogue Reverse-Transcriptase Inhibitor-Associated Lipoatrophy
[作者:Sievers, M; Walker, UA; Sevastianova, K; Setzer, B; Wagsater, D; Eriksson, P; Yki-Jarvinen, H; Sutinen, J,期刊:Journal of Infectious Diseases, 页码:252-262 , 文章类型: Article,,卷期:2009年200-2]
- Background. Long-term use of both zidovudine (AZT) and stavudine (d4T) is associated with lipoatrophy, but it occurs possibly through different mechanisms.Methods. Surgical biopsy specimens of subcutaneous adipose tissue...
- A Live-Attenuated Vaccine for the Treatment of Urinary Tract Infection by Uropathogenic Escherichia coli
[作者:Billips, BK; Yaggie, RE; Cashy, JP; Schaeffer, AJ; Klumpp, DJ,期刊:Journal of Infectious Diseases, 页码:263-272 , 文章类型: Article,,卷期:2009年200-2]
- Uropathogenic Escherichia coli are the leading cause of urinary tract infection. We recently demonstrated that deletion of the O antigen ligase gene, waaL, from the uropathogenic E. coliisolate NU14 results in a strain t...
- Esterase D Is Essential for Protection of Neisseria gonorrhoeae against Nitrosative Stress and for Bacterial Growth during Interaction with Cervical Epithelial Cells
[作者:Potter, AJ; Kidd, SP; Edwards, JL; Falsetta, ML; Apicella, MA; Jennings, MP; McEwan, AG,期刊:Journal of Infectious Diseases, 页码:273-278 , 文章类型: Article,,卷期:2009年200-2]
- estD encodes a carboxylic ester hydrolase and is part of the NmlR regulon in Neisseria gonorrhoeae. An estD mutant was found to be susceptible to nitrite and to S-nitrosoglutathione. This mutant was also unable to infect...
- Human Type 1 and 17 Responses in Latent Tuberculosis Are Modulated by Coincident Filarial Infection through Cytotoxic T Lymphocyte Antigen-4 and Programmed Death-1
[作者:Babu, S; Bhat, SQ; Kumar, NP; Jayantasri, S; Rukmani, S; Kumaran, P; Gopi, PG; Kolappan, C; Kumaraswami, V; Nutman, TB,期刊:Journal of Infectious Diseases, 页码:288-298 , 文章类型: Article,,卷期:2009年200-2]
- Mycobacterium tuberculosis and filarial coinfection is highly prevalent, and the presence of a tissue-invasive helminth may modulate the predominant type 1 T helper (Th1; interferon [IFN]-gamma-mediated) response needed ...
- Antibodies to Variant Surface Antigens of Plasmodium falciparum-Infected Erythrocytes Are Associated with Protection from Treatment Failure and the Development of Anemia in Pregnancy
[作者:Feng, GQ; Aitken, E; Yosaatmadja, F; Kalilani, L; Meshnick, SR; Jaworowski, A; Simpson, JA; Rogerson, SJ,期刊:Journal of Infectious Diseases, 页码:299-306 , 文章类型: Article,,卷期:2009年200-2]
- Background. In pregnancy-associated malaria (PAM), Plasmodium falciparum-infected erythrocytes (IEs) express variant surface antigens (VSA-PAM) that evade existing immunity and mediate placental sequestration. Antibodies...
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