- Intestinal Enterococcus faecium Colonization Improves Host Defense during Polymicrobial Peritonitis
[作者:Leendertse, M; Willems, RJL; Oei, GA; Florquin, S; Bonten, MJM; van der Poll, T,期刊:Journal of Infectious Diseases, 页码:735-744 , 文章类型: Article,,卷期:2009年200-5]
- Background. Vancomycin-resistant (VR) Enterococcus faecium is increasingly found to colonize and infect hospitalized patients. Enterococci are frequently isolated from polymicrobial infections originating from the intest...
- CagA Associates with c-Met, E-Cadherin, and p120-Catenin in a Multiproteic Complex That Suppresses Helicobacter pylori-Induced Cell-Invasive Phenotype
[作者:Oliveira, MJ; Costa, AM; Costa, AC; Ferreira, RM; Sampaio, P; Machado, JC; Seruca, R; Mareel, M; Figueiredo, C,期刊:Journal of Infectious Diseases, 页码:745-755 , 文章类型: Article,,卷期:2009年200-5]
- Background. Helicobacter pylori induces an invasive phenotype in gastric epithelial cells through a mechanism that requires the type IV secretion system and the phosphorylation of c-Met. The E-cadherin-catenin complex is...
- Arcobacter butzleri Induces Barrier Dysfunction in Intestinal HT-29/B6 Cells
[作者:Bucker, R; Troeger, H; Kleer, J; Fromm, M; Schulzke, JD,期刊:Journal of Infectious Diseases, 页码:756-764 , 文章类型: Article,,卷期:2009年200-5]
- Background. Arcobacter butzleri causes watery diarrhea and bacteremia. Although, recently, more cases of diarrhea have been caused by Arcobacter species, very little is known about its pathogenesis, the identification of...
- Receptor for Advanced Glycation End Products Facilitates Host Defense during Escherichia coli-Induced Abdominal Sepsis in Mice
[作者:van Zoelen, MAD; Schmidt, AM; Florquin, S; Meijers, JC; de Beer, R; de Vos, AF; Nawroth, PP; Bierhaus, A; van der Poll, T,期刊:Journal of Infectious Diseases, 页码:765-773 , 文章类型: Article,,卷期:2009年200-5]
- Background. The receptor for advanced glycation end products (RAGE) mediates a variety of inflammatory responses.Methods. To determine the role of RAGE in the innate immune response to abdominal sepsis caused by Escheric...
- Phthiocerol Dimycocerosate Transport Is Required for Resisting Interferon-gamma-Independent Immunity
[作者:Murry, JP; Pandey, AK; Sassetti, CM; Rubin, EJ,期刊:Journal of Infectious Diseases, 页码:774-782 , 文章类型: Article,,卷期:2009年200-5]
- Nitric oxide (NO), which is an important component of immunity to Mycobacterium tuberculosis, has both cytotoxic and immune regulatory functions. We examined the way that this molecule interacts with M. tuberculosis in v...
- T Cell Memory Response to Pneumococcal Protein Antigens in an Area of High Pneumococcal Carriage and Disease
[作者:Mureithi, MW; Finn, A; Ota, MO; Zhang, QB; Davenport, V; Mitchell, TJ; Williams, NA; Adegbola, RA; Heyderman, RS,期刊:Journal of Infectious Diseases, 页码:783-793 , 文章类型: Article,,卷期:2009年200-5]
- Background. Streptococcus pneumoniae is a leading cause of vaccine-preventable disease worldwide. Pneumococcal protein antigens are currently under study as components of potential vaccines that offer protection against ...
- Mucosal Immunity after Vaccination with Monovalent and Trivalent Oral Poliovirus Vaccine in India
[作者:Grassly, NC; Jafari, H; Bahl, S; Durrani, S; Wenger, J; Sutter, RW; Aylward, RB,期刊:Journal of Infectious Diseases, 页码:794-801 , 文章类型: Article,,卷期:2009年200-5]
- Background. Persistent wild-poliovirus transmission, particularly in India, has raised questions about the degree of mucosal immunity induced by oral poliovirus vaccine (OPV) in tropical countries.Methods. Excretion of v...
- Norovirus Illness Is a Global Problem: Emergence and Spread of Norovirus GII.4 Variants, 2001-2007
[作者:Siebenga, JJ; Vennema, H; Zheng, DP; Vinje, J; Lee, BE; Pang, XL; Ho, ECM; Lim, W; Choudekar, A; Broor, S; Halperin, T; Rasool, NBG; Hewitt, J; Greening, GE; Jin, M; Duan, ZJ; Lucero, Y; O'Ryan, M; Hoehne, M; Schreier, E; Ratcliff, RM; White, PA; Iritani, N; Reuter, G; Koopmans, M,期刊:Journal of Infectious Diseases, 页码:802-812 , 文章类型: Article,,卷期:2009年200-5]
- Background. Noroviruses (NoVs) are the most common cause of viral gastroenteritis. Their high incidence and importance in health care facilities result in a great impact on public health. Studies from around the world de...
- Rotavirus Induces a Biphasic Enterotoxic and Cytotoxic Response in Human-Derived Intestinal Enterocytes, Which Is Inhibited by Human Immunoglobulins
[作者:De Marco, G; Bracale, I; Buccigrossi, V; Bruzzese, E; Canani, RB; Polito, G; Ruggeri, FM; Guarino, A,期刊:Journal of Infectious Diseases, 页码:813-819 , 文章类型: Article,,卷期:2009年200-5]
- The mechanisms of diarrhea due to rotavirus infection in humans are not fully understood; no specific therapy is available, but orally administered human serum immunoglobulins are effective in blocking stool output. We a...
- Prion Protein Expression and Release by Mast Cells After Activation
[作者:Haddon, DJ; Hughes, MR; Antignano, F; Westaway, D; Cashman, NR; McNagny, KM,期刊:Journal of Infectious Diseases, 页码:827-831 , 文章类型: Article,,卷期:2009年200-5]
- In this study, we compared hematopoietic stem cells and mast cells, using microarray expression analysis, and identified the cellular prion protein (PrPC) as a potentially novel marker of mast cells. On further investiga...
- A Case Series of 104 Women Infected with HIV-1 via Blood Transfusion Postnatally: High Rate of HIV-1 Transmission to Infants through Breast-Feeding
[作者:Liang, K; Gui, X; Zhang, YZ; Zhuang, K; Meyers, K; Ho, DD,期刊:Journal of Infectious Diseases, 页码:682-686 , 文章类型: Article,,卷期:2009年200-5]
- We investigated transmission of human immunodeficiency virus type 1 (HIV-1) via breast-feeding by 104 Chinese mothers who acquired the infection through blood transfusion postnatally. Of 106 children, 38 (35.8%) were inf...
- Rate of Accumulation of Thymidine Analogue Mutations in Patients Continuing to Receive Virologically Failing Regimens Containing Zidovudine or Stavudine: Implications for Antiretroviral Therapy Programs in Resource-Limited Settings
[作者:Cozzi-Lepri, A; Phillips, AN; Martinez-Picado, J; Monforte, AD; Katlama, C; Hansen, ABE; Horban, A; Bruun, J; Clotet, B; Lundgren, JD,期刊:Journal of Infectious Diseases, 页码:687-697 , 文章类型: Article,,卷期:2009年200-5]
- Background. Because changes in antiretroviral therapy in resource-limited settings (RLSs) are delayed until patients experience immunological or clinical failure, it is important to be able to estimate the consequences i...
- Failure of Treatment with First-Line Lopinavir Boosted with Ritonavir Can Be Explained by Novel Resistance Pathways with Protease Mutation 76V
[作者:Nijhuis, M; Wensing, AMJ; Bierman, WFW; de Jong, D; Kagan, R; Fun, A; Jaspers, CAJJ; Schurink, KAM; van Agtmael, MA; Boucher, CAB,期刊:Journal of Infectious Diseases, 页码:698-709 , 文章类型: Article,,卷期:2009年200-5]
- Background. Virological failure of first-line antiretroviral therapy based on lopinavir boosted with ritonavir (lopinavir/r) has rarely been associated with resistance in protease. We identified a new genotypic resistanc...
- Virological Response to Initial Antiretroviral Regimens Containing Abacavir or Tenofovir
[作者:Bansi, L; Sabin, C; Gilson, R; Gazzard, B; Leen, C; Anderson, J; Dunn, D; Hill, T; Fisher, M; Ainsworth, J; Pillay, D; Johnson, M; Walsh, J; Orkin, C; Easterbrook, P; Gompels, M; Phillips, A,期刊:Journal of Infectious Diseases, 页码:710-714 , 文章类型: Article,,卷期:2009年200-5]
- Patients with a baseline viral load 1100,000 copies/mL receiving abacavir (ABC) as part of the nucleoside-backbone component of their first highly active antiretroviral therapy ( HAART) regimen have been reported to have...
- Phenol-Soluble Modulin alpha 3 Enhances the Human Neutrophil Lysis Mediated by Panton-Valentine Leukocidin
[作者:Hongo, I; Baba, T; Oishi, K; Morimoto, Y; Ito, T; Hiramatsu, K,期刊:Journal of Infectious Diseases, 页码:715-723 , 文章类型: Article,,卷期:2009年200-5]
- Panton-Valentine leukocidin (PVL) has long been considered a critical toxin in severe Staphylococcus aureus infection. PVL presumably breaches the body's defense system by lysing human polymorphonuclear cells (PMNs). Rec...
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