- Safety and Immunogenicity of a Novel Influenza Subunit Vaccine Produced in Mammalian Cell Culture
[作者:Szymczakiewicz-Multanowska, A; Groth, N; Bugarini, R; Lattanzi, M; Casula, D; Hilbert, A; Tsai, T; Podda, A,期刊:Journal of Infectious Diseases, 页码:841-848 , 文章类型: Article,,卷期:2009年200-6]
- Background. Immunization remains the best prevention strategy for influenza, but production constraints for egg-based influenza vaccines have prompted the development of innovative cell culture manufacturing processes. H...
- Subunit Influenza Vaccines Produced from Cell Culture or in Embryonated Chicken Eggs: Comparison of Safety, Reactogenicity, and Immunogenicity
[作者:Reisinger, KS; Block, SL; Izu, A; Groth, N; Holmes, SJ,期刊:Journal of Infectious Diseases, 页码:849-857 , 文章类型: Article,,卷期:2009年200-6]
- Background. This study assessed the safety, reactogenicity, and immunogenicity of an injectable cell culture derived influenza vaccine (CCIV), compared with those of an injectable egg-based trivalent inactivated influenz...
- Phosphoantigen-Expanded Human gamma delta T Cells Display Potent Cytotoxicity against Monocyte-Derived Macrophages Infected with Human and Avian Influenza Viruses
[作者:Qin, G; Mao, HW; Zheng, J; Sia, SF; Liu, YP; Chan, PL; Lam, KT; Peiris, JSM; Lau, YL; Tu, WW,期刊:Journal of Infectious Diseases, 页码:858-865 , 文章类型: Article,,卷期:2009年200-6]
- Background. Influenza virus is a cause of substantial annual morbidity and mortality worldwide. The potential emergence of a new pandemic strain (eg, avian influenza virus) is a major concern. Currently available vaccine...
- Pegylated Interferon and Ribavirin Promote Early Evolution of Nonstructural 5A Protein in Individuals with Hepatitis C Who Demonstrate a Response to Treatment
[作者:Jain, MK; Yuan, HJ; Adams-Huet, B; Reeck, A; Shelton, J; Attar, N; Zhang, S; Neumann, AU; Carney, DS; Gale, M; Lee, WM,期刊:Journal of Infectious Diseases, 页码:866-876 , 文章类型: Article,,卷期:2009年200-6]
- Background. Hepatitis C virus (HCV) quasispecies diversity is more likely to affect early viral decline during treatment of hepatitis C than is having human immunodeficiency virus (HIV) infection. We evaluated the influe...
- Rate of Sustained Virologic Response in Relation to Baseline Hepatitis C Virus (HCV) RNA Level and Rapid Virologic Clearance in Persons with Acute HCV Infection
[作者:McGovern, BH; Nagami, EH; Birch, CE; Bowen, MJ; Reyor, LL; Chung, RT; Kim, AY,期刊:Journal of Infectious Diseases, 页码:877-881 , 文章类型: Article,,卷期:2009年200-6]
- Treatment of acute hepatitis C virus (HCV) infection leads to a sustained virologic response (SVR) in the vast majority of patients, although the clinical predictors of these favorable responses are not well understood. ...
- Concurrent Human Papillomavirus-Associated Tonsillar Carcinoma in 2 Couples
[作者:Andrews, E; Shores, C; Hayes, DN; Couch, M; Southerland, J; Morris, D; Seaman, WT; Webster-Cyriaque, J,期刊:Journal of Infectious Diseases, 页码:882-887 , 文章类型: Article,,卷期:2009年200-6]
- We describe 2 nonsmoking, nondrinking couples who developed human papillomavirus (HPV)-associated tonsillar cancer within 12 months of each other. After histopathologic evaluation, HPV L1, E2, E6, and LCR regions were am...
- Persistence of Rubella Antibodies after 2 Doses of Measles-Mumps-Rubella Vaccine
[作者:LeBaron, CW; Forghani, B; Matter, L; Reef, SE; Beck, C; Bi, DL; Cossen, C; Sullivan, BJ,期刊:Journal of Infectious Diseases, 页码:888-899 , 文章类型: Article,,卷期:2009年200-6]
- Background. Since 1990, most schoolchildren in the United States have received a second dose of measles-mumps-rubella vaccine (MMR2) at kindergarten entry. Elimination of endemic rubella virus circulation in the United S...
- The Role of Patient-to-Patient Transmission in the Acquisition of Imipenem-Resistant Pseudomonas aeruginosa Colonization in the Intensive Care Unit
[作者:Johnson, JK; Smith, G; Lee, MS; Venezia, RA; Stine, OC; Nataro, JP; Hsiao, W; Harris, AD,期刊:Journal of Infectious Diseases, 页码:900-905 , 文章类型: Article,,卷期:2009年200-6]
- Background. Imipenem-resistant Pseudomonas aeruginosa (IRPA) is an emerging problem. The causal role of antibiotic selective pressure versus patient-to-patient transmission has not been assessed using a large cohort.Meth...
- Population-Based Incidence and Etiology of Community-Acquired Neonatal Bacteremia in Mirzapur, Bangladesh: An Observational Study
[作者:Darmstadt, GL; Saha, SK; Choi, Y; El Arifeen, S; Ahmed, NU; Bari, S; Rahman, SM; Mannan, I; Crook, D; Fatima, K; Winch, PJ; Seraji, HR; Begum, N; Rahman, R; Islam, M; Rahman, A; Black, RE; Santosham, M; Sacks, E; Baqui, AH,期刊:Journal of Infectious Diseases, 页码:906-915 , 文章类型: Article,,卷期:2009年200-6]
- Background. To devise treatment strategies for neonatal infections, the population-level incidence and antibiotic susceptibility of pathogens must be defined.Methods. Surveillance for suspected neonatal sepsis was conduc...
- Induction of microRNA-155 during Helicobacter pylori Infection and Its Negative Regulatory Role in the Inflammatory Response
[作者:Xiao, B; Liu, Z; Li, BS; Tang, B; Li, W; Guo, G; Shi, Y; Wang, FJ; Wu, Y; Tong, WD; Guo, H; Mao, XH; Zou, QM,期刊:Journal of Infectious Diseases, 页码:916-925 , 文章类型: Article,,卷期:2009年200-6]
- Background. MicroRNAs (miRNAs) are small, noncoding RNAs that regulate gene expression at posttranscriptional level. H. pylori is a major human pathogenic bacterium in gastric mucosa. To date, the role of miRNAs in respo...
- Role of T Lymphocytes in the Pathogenesis of Chlamydia Disease
[作者:Igietseme, JU; He, Q; Joseph, K; Eko, FO; Lyn, D; Ananaba, G; Campbell, A; Bandea, C; Black, CM,期刊:Journal of Infectious Diseases, 页码:926-934 , 文章类型: Article,,卷期:2009年200-6]
- Vaccines are needed to prevent the oculogenital diseases of Chlamydia trachomatis. Infected hosts develop immunity, although temporary, and experimental vaccines have yielded significant protective immunity in animal mod...
- Immunogenicity and Immunologic Memory after Hepatitis B Virus Booster Vaccination in HIV-Infected Children Receiving Highly Active Antiretroviral Therapy
[作者:Abzug, MJ; Warshaw, M; Rosenblatt, HM; Levin, MJ; Nachman, SA; Pelton, SI; Borkowsky, W; Fenton, T,期刊:Journal of Infectious Diseases, 页码:935-946 , 文章类型: Article,,卷期:2009年200-6]
- Background. Hepatitis B virus (HBV) is an important cause of comorbidity in human immunodeficiency virus (HIV)-infected individuals. The immunogenicity of HBV vaccination in children receiving highly active antiretrovira...
- CYP2B6 Variants and Plasma Efavirenz Concentrations during Antiretroviral Therapy in Port-au-Prince, Haiti
[作者:Leger, P; Dillingham, R; Beauharnais, CA; Kashuba, ADM; Rezk, NL; Fitzgerald, DW; Pape, JW; Haas, DW,期刊:Journal of Infectious Diseases, 页码:955-964 , 文章类型: Article,,卷期:2009年200-6]
- Background. Polymorphisms in CYP2B6 are known to predict increased steady-state plasma concentrations of efavirenz. We characterized relationships between genetic polymorphisms and plasma efavirenz concentrations among 4...
- HIV Type 1 Infection in Women: Increased Transcription of HIV Type 1 in Ectocervical Tissue Explants
[作者:Asin, SN; Eszterhas, SK; Rollenhagen, C; Heimberg, AM; Howell, AL,期刊:Journal of Infectious Diseases, 页码:965-972 , 文章类型: Article,,卷期:2009年200-6]
- Background. Mucosal surfaces of the female reproductive tract are the main routes of heterosexual transmission of human immunodeficiency virus type 1 (HIV-1), but the contribution of each of the reproductive sites to muc...
- Activation and Coagulation Biomarkers Are Independent Predictors of the Development of Opportunistic Disease in Patients with HIV Infection
[作者:Rodger, AJ; Fox, Z; Lundgren, JD; Kuller, LH; Boesecke, C; Gey, D; Skoutelis, A; Goetz, MB; Phillips, AN,期刊:Journal of Infectious Diseases, 页码:973-983 , 文章类型: Article,,卷期:2009年200-6]
- Activation and coagulation biomarkers were measured within the Strategies for Management of Antiretroviral Therapy (SMART) trial. Their associations with opportunistic disease (OD) in human immunodeficiency virus (HIV)-p...
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