- GOLPH3 Bridges Phosphatidylinositol-4-Phosphate and Actomyosin to Stretch and Shape the Golgi to Promote Budding
[作者:Dippold, HC; Ng, MM; Farber-Katz, SE; Lee, SK; Kerr, ML; Peterman, MC; Sim, R; Wiharto, PA; Galbraith, KA; Madhavarapu, S; Fuchs, GJ; Meerloo, T; Farquhar, MG; Zhou, HL; Field, SJ,期刊:Cell, 页码:337-351 , 文章类型: Article,,卷期:2009年139-2]
- Golgi membranes, from yeast to humans, are uniquely enriched in phosphatidylinositol-4-phosphate (PtdIns(4)P), although the role of this lipid remains poorly understood. Using a proteomic lipid-binding screen, we identif...
- GPI Glycan Remodeling by PGAP5 Regulates Transport of GPI-Anchored Proteins from the ER to the Golgi
[作者:Fujita, M; Maeda, Y; Ra, M; Yamaguchi, Y; Taguchi, R; Kinoshita, T,期刊:Cell, 页码:352-365 , 文章类型: Article,,卷期:2009年139-2]
- Many eukaryotic proteins are attached to the cell surface via glycosylphosphatidylinositol (GPI) anchors. How GPI-anchored proteins (GPI-APs) are trafficked from the endoplasmic reticulum (ER) to the cell surface is poor...
- Schwann Cell Precursors from Nerve Innervation Are a Cellular Origin of Melanocytes in Skin
[作者:Adameyko, I; Lallemend, F; Aquino, JB; Pereira, JA; Topilko, P; Muller, T; Fritz, N; Beljajeva, A; Mochii, M; Liste, I; Usoskin, D; Suter, U; Birchmeier, C; Ernfors, P,期刊:Cell, 页码:366-379 , 文章类型: Article,,卷期:2009年139-2]
- Current opinion holds that pigment cells, melanocytes, are derived from neural crest cells produced at the dorsal neural tube and that migrate under the epidermis to populate all parts of the skin. Here, we identify grow...
- Gabapentin Receptor alpha 2 delta-1 Is a Neuronal Thrombospondin Receptor Responsible for Excitatory CNS Synaptogenesis
[作者:Eroglu, C; Allen, NJ; Susman, MW; O'Rourke, NA; Park, CY; Ozkan, E; Chakraborty, C; Mulinyawe, SB; Annis, DS; Huberman, AD; Green, EM; Lawler, J; Dolmetsch, R; Garcia, KC; Smith, SJ; Luo, ZD; Rosenthal, A; Mosher, DF; Barres, BA,期刊:Cell, 页码:380-392 , 文章类型: Article,,卷期:2009年139-2]
- Synapses are asymmetric cellular adhesions that are critical for nervous system development and function, but the mechanisms that induce their formation are not well understood. We have previously identified thrombospond...
- Trans-Synaptic Transmission of Vesicular Wnt Signals through Evi/Wntless
[作者:Korkut, C; Ataman, B; Ramachandran, P; Ashley, J; Barria, R; Gherbesi, N; Budnik, V,期刊:Cell, 页码:393-404 , 文章类型: Article,,卷期:2009年139-2]
- Wnts play pivotal roles during development and in the mature nervous system. However, the mechanism by which Wnts traffic between cells has remained elusive. Here we demonstrate a mechanism of Wnt transmission through re...
- Writing Memories with Light-Addressable Reinforcement Circuitry
[作者:Claridge-Chang, A; Roorda, RD; Vrontou, E; Sjulson, L; Li, HY; Hirsh, J; Miesenbock, G,期刊:Cell, 页码:405-415 , 文章类型: Article,,卷期:2009年139-2]
- Dopaminergic neurons are thought to drive learning by signaling changes in the expectations of salient events, such as rewards or punishments. Olfactory conditioning in Drosophila requires direct dopamine action on intri...
- A Neural Circuit Mechanism Integrating Motivational State with Memory Expression in Drosophila
[作者:Krashes, MJ; DasGupta, S; Vreede, A; White, B; Armstrong, JD; Waddell, S,期刊:Cell, 页码:416-427 , 文章类型: Article,,卷期:2009年139-2]
- Behavioral expression of food-associated memory in fruit flies is constrained by satiety and promoted by hunger, suggesting an influence of motivational state. Here, we identify a neural mechanism that integrates the int...
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